Graduate School of Medicine / Faculty of Medicine, Osaka University

JAPANESE

Health Sciences Research

Introduction of Research in the Division of Health Sciences

Area of Nursing Science

Allied Health Sciences and Nursing carry out research activities to support people to autonomously protect their health, from the perspective of clinical services as well as health promotion.
Research activities are extensive: verification and development of nursing diagnostics and nursing techniques, psychological aspects of patients and families, wellness support for infants and prenatal women, support for intractable disease patients and physically-challenged people, joint research with the local government regarding elderly care and long-term care insurance system, development of a smoking education program, and development of industrial health and health science indices.

Many faculty members don't contain their activities just to the campus. They are instrumental in cooperating with administrative bodies, such as local governments, for implementation and verification of health and welfare measures and also in contributing to various policy-making committees in the field of health and welfare.

In research regarding elderly care, the behavioral analysis uses electronic devices, such as IC tags for elderly people with challenges such as dementia. In Development of Care Devices, we are engaged in unique research with private companies, such as the development of nursing devices, mats, and uniforms.

In the Research of Smoking Control Education Program, the Non-Smoking promotion initiative and research is currently underway. Every year, the School of Health Sciences carries out surveys among students to learn about the consciousness and knowledge of tobacco. At the same time, practical education and research based on the educational program are provided to the nursing students to develop professionals who support non-smoking. Before and after these programs, we verify the effect to confirm validity of the education program.
The demand for activities to grow professionals who can engage in non-smoking activities will increase in the future.
(http://sahswww.med.osaka-u.ac.jp/www/syokai/kango.html)

Medical Technology and Science Field

Ministry of Health, Labor and Welfare Grant-in-Aid for Scientific Research 2004
‘Development of cancer immunotherapy using WT1 cancer antigen peptide'
(Professor SUGIYAMA Haruo)

Cancer is a threatening disease with a high fatality rate. Many cancers are left with poor treatment results. People are waiting for the development of treatments based on new strategies. Recently, attention is being paid to immunotherapy, which stimulates and strengthens the immune system, innate to our system, in order to eliminate cancer cells.

Professor SUGIYAMA Haruo is engaged in the development of "Cancer Immunotherapy to target Wilm's tumor gene (WT1)." The development started with the discovery, by Professor SUGIYAMA and other members, that WT1 is over-expressed in leukemia, a cancer of blood cells. Based on this discovery, the' WT1 test' was developed as a highly sensitive tumor marker which is now inevitable for diagnosing and judging the effect of leukemia therapy. Furthermore, Professor SUGIYAMA and other members discovered that the WT1 tumor gene is abhorrently expressed in various solid cancers such as lungs, colon, esophagus, tongue, and pancreas as well as in malignant brain tumors. And they also discovered that the product of solid cancer becomes cancer antigen, which is a target used by immune cells to attack cancer cells.

Currently, clinical tests are being carried out with numerous patients using' Cancer Immunotherapy with the target of WT1' in Osaka University Hospital. There have been some cases where this immunotherapy demonstrated clinical effects on patients with whom no surgeries and chemotherapy worked.
(http://sahswww.med.osaka-u.ac.jp/~hmtonc/)