Osaka University Medical School joins Takara Bio and Thermo Fisher Scientific in cancer clinical sequencing project
Osaka University Medical School has announced a new collaborative project with Takara Bio and Thermo Fischer Scientific that will generate cancer clinical sequences※1. In recognition of its high status in the field of cancer medicine, Osaka University Hospital was recognized by the Ministry of Health, Labour and Welfare as a Designated Core Hospital for Cancer Genomic Medicine this past April.
The project aims to create a basis for new genomic medicine※2 and diagnostics for cancer.
The three organizations will be working together at the Osaka University Hospital Clinical Sequencing Laboratory. Thermo Fischer Scientific will provide its cancer gene panel※3, the Oncomine Target Test※4, which can detect multiple gene mutations in a single test from a single tissue sample, while Takara Bio will process the data from next generation sequencers※5. Expert panel※6 (specialized staff) at Osaka University Hospital will interpret the results. Following this clinical research, the parties will apply for regulatory approval for patient treatment.
The Clinical Sequencing Laboratory is Japan’s first facility to be CAP-LAP※7 compliant (CLIA※8 compliant), which means our approach meets the standards of the FDA in the United States.
※1 Cancer clinical sequence
A patient’s DNA sequence that is used to determine the treatment strategy against cancer.
※2 Genomic medicine
The use of the patient’s own genomic information for treatment.
※3 Cancer gene panel
An assay for the analysis of multiple cancer-related genes from patient samples.
※4 Oncomine Target Test
An FDA-approved cancer gene panel manufactured by Thermo Fisher Scientific.
※5 next generation sequencers
Technologies that can sequence DNA and RNA at high speed and low cost.
※6 Expert panel
Expertise includes knowledge in cancer medicine genomic medicine, genetic counselling, bioinformatics and more.
CAP (College of American Pathologist) provides LAP (Laboratory Accreditation Program), which is the largest program of its type and has credentials recognized globally for clinical laboratory management.
※8 CLIA (Clinical Laboratory Improvement Amendments)
CMS (Center for Medicare & Medicaid Services) is U.S. government organization responsible for defining standards regarding the handling of human specimens by clinical laboratories.