Advanced visual neuroscience
- Research of retinal prosthesis systems, evalution of their function, and use in rehabilitation
- Research on neuroprotection mechanisms to prevent eye diseases
- Research on the pathogenesis and functional repair of eye diseases
- Research on vision function and new eye treatments
Vision restoration with the use of retinal prosthesis
1. Research and development of retinal prostheses:
We are conducting research on retinal prosthesis systems using suprachoroidal-transretinal stimulation (STS) for advanced outer retinal degeneration. Our research plan includes animal models, and we are scheduled to begin a multicenter clinical trial in 2021. Part of this research includes developing next-generation retinal prostheses, such as dual-array electrode plates.
In addition, we are researching ways to evaluate and rehabilitate vision function with retinal prosthesis in different patient populations, such as those in which the artificial retinas are implanted and others in which they simply wear the retina (e.g. contact lens).
2. Research on neuroprotective strategies against eye diseases:
We have been investigating the neuroprotective effects of electrically stimulating the eyes. Our next goal is to develop a new implant device and develop new neuroprotective therapeutic strategies.
3. Research on the functional repair and pathophysiology of eye diseases:
We are using several imaging techniques such as optical coherence tomography (OCT) and adaptive optics fundus cameras along with genome analysis to elucidate the pathophysiology of several eye diseases and discover potential repair mechanisms.
4. Analysis of vision function and new treatments:
Excessive smartphone use is resulting in a significant and rapid rise in the number of presbyopia and strabismus patients. In general, eye diseases associated with screen time are becoming more prevalent. This rise is attributed to eye fatigue, which requires more study for both the cause and treatment. Another field of interest is visual function in sports, which has been difficult to study in real world conditions. We are developing experimental methods that will be used to evaluate and maximize visual functions in these conditions.