Department of Internal Medicine

Geriatric and General Medicine

New medical approaches for healthy longevity
  • The mechanisms of physical changes with age
  • Study of age-related diseases and new treatments
  • Measures for healthy longevity
  • Mechanisms of dementia and new treatment methods
  • Education of future doctors for next-generation geriatric care
Professor Hiromi Rakugi
Geriatric and General Medicine
The lab was founded in 1976 and is recognized as having clarified the pathology of progeria along with identifying and analyzing genes involved in age-related hypertension and diabetes. Overall, the lab takes interest in age-related diseases.

The lab is attending age-related diseases such as dementia and sarcopenia along with lifestyle diseases (diabetes, etc.)

Aging changes the body and the risk for disease. We are searching for measures that promote healthy longevity. Japan is already the world’s oldest society, and estimates anticipate that by 2050 over 40% of its population will be elderly. While not as severe, these trends hold for many industrialized countries, which makes these age-related ailments an international concern.

The lab has broken its research into four categories: dementia, diabetes and other metabolic diseases, hypertension, and general medicine (see Image). Although clinically speaking these categories are distinct, the research of each shares the common goal of sustaining a healthy and productive society. The research entails elucidating age-related molecular mechanisms for disease, establishing new treatment methods, improving the post-surgery prognosis of elderly patients, and reducing drug side-events.


The clinical work of the lab can be divided into geriatric and general medicine. However, based on the 4 categories outlined above, our doctors have backgrounds in at least one specialty, such as dementia, hypertension, endocrinology, etc. The lab is also devoted to training future doctors that can contribute to solving age-related problems.