☆　2000

1. Miyahara, M., Nakanishi, H., Takahashi, K., Satoh-Horikawa, K., Tachibana, K., and Takai, Y. (2000)
   Interaction of nectin with afadin is necessary for its clustering at cell-cell contact sites but not for its cis dimerization or trans interaction.
   J. Biol. Chem., 275, 613-618
   
   
2. Hirao, K., Hata, Y., Yao, I., Deguchi, M., Kawabe, H., Mizoguchi, A., and Takai, Y. (2000)
   Three isoforms of synaptic scaffolding molecule and their characterization. Multimerization between the isoforms and their interaction with N-methyl-D-aspartate receptors and SAP90/PSD-95-associated protein.
   J. Biol. Chem., 275, 2966-2972
   
   
3. Satoh-Horikawa, K., Nakanishi, H., Takahashi, K., Miyahara, M., Nishimura, M., Tachibana, K., Mizoguchi, A., and Takai, Y. (2000)
   Nectin-3: A new member of immunoglobulin-like cell adhesion molecules that shows homophilic and heterophilic cell-cell adhesion activities.
   J. Biol. Chem., 275, 10291-10299
   
   
4. Mammoto, A., Sasaki, T., Kim, Y., and Takai, Y. (2000)
   Physical and functional interaction of rabphilin-11 with mammalian Sec13 protein. Implication in vesicle trafficking.
   J. Biol. Chem., 275, 13167-13170
   
   
5. Deguchi, M., Iizuka, T., Hata, Y., Nishimura, W., Hirao, K., Yao, I., Kawabe, H., and Takai, Y. (2000)
   PAPIN. A novel multiple PSD-95/Dlg-A/ZO-1 protein interacting with neural plakophilin-related armadillo repeat protein/δ-catenin and p0071.
   J. Biol. Chem., 275, 29875-29880
   
   
6. Tachibana, K., Nakanishi, H., Mandai, K., Ozaki, K., Ikeda, W., Nagafuchi, A., Tsukita, S., and Takai, Y. (2000)
   Two cell adhesion molecules, Nectin and Cadherin, interact through their cytoplasmic domain-associated proteins.
   J. Cell Biol., 150, 1161-1176
   
   
7. Hibino, H., Inanobe, A., Tanemoto, M., Fujita, A., Doi, K., Kubo, T., Hata, Y., Takai, Y., and Kurachi Y. (2000)
   Anchoring proteins confer G protein sensitivity to an inward-rectifier K⁺ channel through the GK domain.
   EMBO J., 19, 78-83
   
   
8. Ishizaki, H., Miyoshi, J., Kamiya, H., Togawa, A., Tanaka, M., Sasaki, T., Endo, K., Mizoguchi, A., Ozawa, S., and Takai, Y. (2000)
   Role of Rab GDIα regulating plasticity of hippocampal neurotramsmission.
   Proc. Natl. Acad. Sci. USA, 97, 11587-11592
   
9. Takakura, A., Miyoshi, J., Ishizaki, H., Tanaka, M., Togawa, A., Nishizawa, Y., Yoshida, H., Nishikawa, S., and Takai, Y. (2000)
   Involvement of a small GTP-binding protein (G protein) regulator, small G protein GDP dissociation stimulator, in antiapoptotic cell survival signaling.
   Mol. Biol. Cell, 11, 1875-1886
   
   
10. Kodama, A., Matozaki, T., Fukuhara, A., Kikyo, M., Ichihashi, M., and Takai, Y., (2000)
    Involvement of an SHP-2-Rho small G protein pathway in hepatocyte growth factor/scatter factor-induced cell scattering.
    Mol. Biol. Cell, 11, 2565-2575
    
    
11. Ono, Y., Nakanishi, H., Nishimura, M., Kakizaki, M., Takahashi, K., Miyahara, M., Satoh-Horikawa, K., Mandai, K., and Takai, Y. (2000)
    Two actions of frabin: direct activation of Cdc42 and indirect activation of Rac.
    Oncogene, 19, 3050-3058
    
    
12. Kikyo, M., Matozaki, T., Kodama, A., Kawabe, H., Nakanishi, H., and Takai, Y. (2000)
    Cell-cell adhesion-mediated tyrosine phosphorylation of nectin-2δ, an immunoglobulin-like cell adhesion molecule at adherens junctions.
    Oncogene, 19, 4022-4028
    
    
13. Yao, I., Ohtsuka, T., Kawabe, H., Matsuura, Y., Takai, Y., and Hata, Y. (2000)
    Association of membrane-associated guanylate kinase-interacting protein-1 with Raf-1.
    Biochem. Biophys. Res. Commun., 270, 538-542
    
    
14. Fujiwara, T., Mammoto, A., Kim, Y., and Takai, Y. (2000)
    Rho small G-protein-dependent binding of mDia to an Src homology 3 domain-containing IRSp53/BAIAP2.
    Biochem. Biophys. Res. Commun., 271, 626-629
    
    
15. Takaishi, K., Mino, A., Ikeda, W., Nakano, K., and Takai, Y. (2000)
    Mechanisms of activation and action of mDial in the formation of parallel stress fibers in MDCK cells.
    Biochem. Biophys. Res. Commun., 274, 68-72
    
    
16. Hirao, K., Hata, Y., Deguchi, M., Yao, I., Ogura, M., Rokukawa, C., Kawabe. H., Mizoguchi, A., and Takai, Y. (2000)
    Association of synapse-associated protein 90/postsynaptic density-95-associated protein (SAPAP) with neurofilaments.
    Genes Cells, 5, 203-210
    
    
17. Yasuda, T., Ohtsuka, T., Inoue, E., Yokoyama, S., Sakisaka T., Kodama , A., Takaishi, K., and Takai, Y. (2000)
    Importance of spatial activation of Cdc42 and Rac small G proteins by frabin for microspike in MDCK cells.
    Genes Cells, 5, 583-591
    
    
18. Takaishi, K., Matozaki, T., Nakano, K., and Takai, Y. (2000)
    Multiple downstream signalling pathways from ROCK, a target molecule of Rho small G protein, in reorganization of the actin cytoskeleton in Madin-Darby canine kidney cells.
    Genes Cells, 5, 929-936
    
    
19. Peng, Y.F., Mandai, K., Sakisaka, T., Okabe, N., Yamamoto, Y., Yokoyama, S., Mizoguchi, A., Shiozaki, H., Monden, M., and Takai, Y. (2000)
    Ankycorbin: A novel actin cytoskeleton-associated protein.
    Genes Cells, 5, 1001-1008
    
    
20. Mino, A., Ohtsuka, T., Inoue, E., and Takai, Y. (2000)
    Membrane-associated guanylate kinase with inverted orientation(MAGI)-1/brain angiogenesis inhibitor 1-associated protein(BAP1) as a scaffolding molecule for Rap small G protein GDP/GTP exchange protein at tight junctions.
    Genes Cells, 5, 1009-1016
    
    
21. Suzuki, T., Mimuro, H., Miki, H., Takenawa, T., Sasaki, T., Nakanishi, H., Takai, Y., and Sasakawa, C. (2000)
    Rho family GTPase Cdc42 is essential for the actin-based motility of Shigella in mammalian cells.
    J. Exp. Med., 191, 1905-1920
    
    
22. Nishioka, H., Mizoguchi, A., Nakanishi, H., Mandai, K., Takahashi, K., Kimura, K., Satoh-Moriya, A., and Takai, Y. (2000)
    Localization of l-Afadin at puncta adhaerentia-like junctions between the mossy fiber terminals and the dendritic trunks of pyramidal cells in the adult mouse hippocampus.
    J. Comp. Neurol., 424, 297-306
    
    
23. Ozaki, N., Shibasaki, T., Kashima, Y., Miki, T., Takahashi, K., Ueno, H., Sunaga, Y., Yano, H., Matsuura, Y., Iwanaga, T., Takai, Y. and Seino, S. (2000)
    cAMP-GEFII is a direct target of cAMP in regulated exocytosis.
    Nature Cell Biol., 2, 805-811
    
    
24. Mammoto A., Takahashi, K., Sasaki, T., and Takai, Y. (2000)
    Stimulation of Rho GDI release by ERM proteins.
    Methods Enzymol., 325, 91-101
    
    
25. Matozaki, T., Nakanishi. H., and Takai, Y. (2000)
    Small G protein networks: Their crosstalks and signal cascades.
    Cellular Signalling, 12, 515-524