☆　2004

1. Ikeda, W., Kakunaga, S., Takekuni, K., Shingai, T., Satoh, K., Morimoto, K., Takeuchi, M., Imai, T., and Takai, Y. (2004)
   Nectin-like molecule-5/Tage4 enhances cell migration in an integrin-dependent, nectin-3-independent manner.
   J. Biol. Chem., 279, 17, 18015-18025
   
   
2. Ooshio, T., Irie, K., Morimoto, K., Fukuhara, A., Imai, T., and Takai, Y. (2004)
   Involvement of LMO7 in the association of two cell-cell adhesion molecules, nectin and E-cadherin, through afadin and a-actinin in epithelial cells.
   J. Biol. Chem., 279, 31365-31373
   
   
3. Kakunaga, S., Ikeda, W., Shingai, T., Fujito, T., Yamada, A., Minami, Y., Imai, T., and Takai, Y. (2004)
   Enhancement of serum- and platelet-derived growth factor-induced cell proliferation by Necl-5/Tage4/Poliovirus Receptor/CD155 through the Ras-Raf-MEK-ERK signaling.
   J. Biol. Chem., 279, 36419-36425
   
   
4. Takao-Rikitsu, E., Mochida, S., Inoue, E., Deguchi-Tawarada, M., Inoue, M., Ohtsuka, T., and Takai, Y. (2004)
   Physical and functional interaction of the active zone proteins, CAST, RIM1, and Bassoon, in neurotransmitter release.
   J. Cell Biol., 164, 301-311
   
   
5. Sakisaka, T., Baba, T., Tanaka, S., Izumi, G., Yasumi, M., and Takai, Y. (2004)
   Regulation of SNAREs by tomosyn and ROCK: Implication in extension and retraction of neurite
   J. Cell Biol., 166, 17-25
   
   
6. Izumi, G., Sakisaka, T., Baba, T., Tanaka, S., Morimoto, K., and Takai, Y. (2004)
   Endocytosis of E-cadherin regulated by Rac and Cdc42 small G proteins through IQGAP1 and actin filaments.
   J. Cell Biol., 166, 237-248
   
   
7. Fukuhara, T., Shimizu, K., Kawakatsu, T., Fukuyama, T., Minami, Y., Honda, T., Hoshino, T., Yamada, T., Ogita, H., Okada, M., and Takai, Y. (2004)
   Activation of Cdc42 by trans interactions of the cell adhesion molecules nectins through c-Src and Cdc42-GEF FRG.
   J. Cell Biol., 166, 393-405
   
   
8. Hoshino, T., Shimizu, K., Honda, T., Kawakatsu, T., Fukuyama, T., Nakamura, T., Matsuda, M., and Takai, Y. (2004)
   A novel role of nectins in inhibition of the E-cadherin-induced activation of Rac and formation of cell-cell adherens junctions.
   Mol. Biol. Cell, 15, 1077-1088
   
   
9. Yamamoto, Y., Irie, K., Asada, M., Mino, A., Mandai, K., and Takai, Y. (2004)
   Direct binding of the human homologue of the Drosophila disc large tumor suppressor gene to seven-pass transmembrane proteins, tumor endothelial marker 5 (TEM5) and a novel TEM5-like protein.
   Oncogene, 23, 3889-3897
   
   
10. Yamamoto, Y., Irie, K., Kurihara, H., Sakai, T., and Takai, Y. (2004)
    Vmac: A novel protein associated with vimentin-type intermediate filament in podocytes of rat kidney.
    Biochem. Biophys. Res. Commun., 315, 1120-1125
    
    
11. Asada, M., Irie, K., Yamada, A., and Takai, Y. (2004)
    Afadin- and a-actinin-binding protein ADIP directly binds bﾕ-COP, a subunit of the coatomer complex.
    Biochem. Biophys. Res. Commun., 321, 350-354
    
    
12. Deguchi-Tawarada, M., Inoue, E., Takao-Rikitsu, E., Inoue, M., Ohtsuka, T., and Takai, Y. (2004)
    CAST2: Identification and characterization of a protein structurally related to the presynaptic cytomatrix protein CAST.
    Genes Cells, 9, 15-23
    
    
13. Sato, T., Irie, K., Ooshio, T., Ikeda, W., and Takai, Y. (2004)
    Involvement of heterophilic trans-interaction of Necl-5/Tage4/PVR/CD155 with nectin-3 in formation of nectin- and cadherin-based adherens junctions.
    Genes Cells, 9, 791-799
    
    
14. Yamada, A., Irie, K., Fukuhara, A., Ooshio, T., and Takai, Y. (2004)
    Requirement of the actin cytoskeleton for the association of nectins with other cell adhesion molecules at adherens and tight junctions in MDCK cells.
    Genes Cells, 9, 843-855
    
    
15. Okabe, N., Shimizu, K., Ozaki-Kuroda, K., Nakanishi, H., Morimoto, K., Takeuchi, M., Katsumaru, H., Murakami, F., and Takai, Y. (2004)
    Contacts between the commissural axons and the floor plate cells are mediated by nectins.
    Dev. Biol., 273, 244-256
    
    
16. Okabe, N., Ozaki-Kuroda, K., Nakanishi, H., Shimizu, K., and Takai, Y. (2004)
    Expression patterns of nectins and afadin during epithelial remodeling in the mouse embryo.
    Dev. Dyn., 230, 174-186
    
    
17. Gandhi, P.N., Gibson, R.M., Tong, X., Miyoshi, J., Takai, Y., Konieczkowski, M., Sedor, J.R., and Wilson-Delfosse, A.L. (2004)
    An activating mutant of Rac1 that fails to interact with Rho GDP-dissociation inhibitor stimulates membrane ruffling in mammalian cells.
    Biochem. J., 378, 409-419
    
    
18. Guttman, J.A., Takai, Y., and Vogl, A.W. (2004)
    Evidence that tubulobulbar complexes in the seminiferous epithelium are involved with internalization of adhesion junctions.
    Biology of Reproduction, 71, 548-559
    
    
19. Gibson, R.M., Tong, X., Gandhi, P.N., Miyoshi, J., Takai, Y., Konieczkowski, M., Sedor, J.R., and Wilson-Delforsse, A.L. (2004)
    An activating mutant of Cdc42 that fails to interact with Rho GDP-dissociation inhibitor localizes to the plasma membrane and mediates actin reorganization.
    Exp. Cell Res., 301, 211-222
    
    
20. Sakisaka, T., and Takai, Y. (2004)
    Biology and pathology of nectins and nectin-like molecules.
    Curr. Opin. Cell Biol., 16, 513-521
    
    
21. Irie, K., Shimizu, K., Sakisaka, T., Ikeda, W., and Takai, Y. (2004)
    Roles and modes of action of nectins in cell-cell adhesion.
    Seminars in Cell & Dev. Biol., 15, 643-656
    
    
22. Miyoshi, J., and Takai, Y. (2004)
    Dual role of DENN/MADD/Rab3GEP in neurotransmission and neuroprotection.
    Trends in Mol. Med., 10, 476-480
    
    
23. Nakanishi, H., and Takai, Y. (2004)
    Role of nectins in cell adhesion, migration, and polarization.
    Biological Chem., 385, 885-892
    
    
24. Irie, K., Shimizu, K., Sakisaka, T., Ikeda, W., and Takai, Y. (2004)
    Roles of nectins in cell adhesion, signaling and polarization.
    Handbook of Experimental Pharmacology, 165, 343-372