1. Molecular mechanisms underlying lymphocyte trafficking into various tissues
2. Search for novel adhesion molecules, chemokines, chemokine receptors and lysophosphatidic acids involved in lymphocyte trafficking across high endothelial venules
3. Search for novel molecule that regulate differentiation of high endothelial venules endothelial cells
4. Mechanism underlying hematogenous dissemination/metastasis of tumor cells
5. Molecular mechanisms underlying tumor cell transmigration across lymphatic endothelial cells
6 Visualization of lymphocyte trafficking into tissues
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