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| 当科の紹介 > 業績 | 平成13年度|

教授挨拶

◆平成13年度◆
| 総説(書籍) | 総説(雑誌) | 原著(邦文) | 原著(英文) | 目次へ戻る |
総説(書籍)

1.ビタミンD受容体を介する転写調節  宮内芳輝※,大薗恵一
松本俊夫編,メディカルレビュー社,東京,p.185−199,2001.

2.ビタミンD不応症   大薗恵一
遺伝子検査外注早わかり辞典,中外医学社,東京,p.63,2001.

総説(雑誌) ↑上へ戻る

1.骨粗鬆症,くる病の治療  大薗恵一
小児内科,33(2):189−194,2001.

2.薬物療法と骨代謝異常  中島滋郎
小児内科,33(2):233−237,2001.

3.Helicobacter pylori の診断  沢田 敦
小児内科,33(3):354−356,2001.

4.Von Gierke 病  乾 幸治
小児内科,33(7):929−934,2001.

5.小児Helicobacter pylori 感染症の治療  田尻 仁
臨床と研究,78(12):129−130,2001.

6.骨代謝疾患の出生前診断  大薗恵一
THE BONE,15(6):23−26,2001.

7.繰り返す骨折 ─ 小児科の立場から ─  島 雅昭
THE BONE,15(6):45−48,2001.

8.Fanconi-Bickel 症候群 (糖原病XI 型)2例の臨床的検討  乾 幸治,中島滋郎
特殊ミルク情報,37:10−15,2001.

9.小児HCV感染  三善陽子,田尻 仁
日本臨床,59(7):1294−1298,2001.

10.胃潰瘍・十二指腸潰瘍  沢田 敦,田尻 仁
小児科臨床,54(4):581−585,2001.

11.嘔吐(胃腸炎・急性腹症)  沢田 敦,田尻 仁
小児科,42(4):611−614,2001.

12.糖原病の遺伝子型と患者管理の進歩  乾 幸治
小児科,42(11):1764−1770,2001.

13.ガラクトース血症の治療  塚本浩子,乾 幸治
小児科,42(12):1883−1889,2001.

14.小児期のTTウイルス感染の臨床的検討  田尻 仁
臨床とウイルス,29(3):114−118,2001.

15.ビタミンDの免疫調節作用  峙 善子※,大薗恵一
腎と骨代謝,14(1):141−148,2001.

16.Pulmonary Arteriovenous Malformation  松下 享
日本小児循環器学会雑誌,17(4):548−549,2001.

17.小児疾患の診断治療基準 ─ ビタミンD代謝異常症 ─  大薗恵一
小児内科,33(増刊号):110−111,2001.

18.小児疾患の診断治療基準 ─ 慢性肝炎 ─  古座岩宏輔,田尻 仁
小児内科,33(増刊号):412−413,2001.

19.小児の症候群 ─ Riley-Day症候群 ─  乾 幸治
小児科診療,64(増刊号):125,2001.

20.小児の症候群 ─ Cockayne症候群 ─  乾 幸治
小児科診療,64(増刊号):266,2001.

21.小児の症候群 ─ Achondroplasia,hypochondroplasia ─  大薗恵一
小児科診療,64(増刊号): 386,2001.

22.小児の症候群 ─ Hypophosphatasia ─  大薗恵一
小児科診療,64(増刊号): 401,2001.

23.小児の症候群 ─ Thanatophoric dysplasia ─  大薗恵一
小児科診療,64(増刊号): 425,2001.

24.消化管疾患と成長障害  三善陽子,田尻 仁
小児科診療,64(6):859−864,2001.

25.骨代謝疾患 ─ くる病 ─  大薗恵一
整形外科,52(8):948−953,2001.

26.骨系統疾患  大薗恵一
マルホ整形外科セミナー,147:35−37,2001.

27.AGEs (advanced glycation endproducts)と無形成骨  山本威久※,大薗恵一
CLINICAL CALCIUM,11(8):54−57,2001.

28.副甲状腺ホルモン抵抗性をもたらす遺伝子異常  大薗恵一
CLINICAL CALCIUM,11(12):87−92,2001.

29.低フォスファターゼ症  大薗恵一,内橋隆行※
ホルモンと臨床,49(3):53−58,2001.

30.Fanconi 症候群  中島滋郎
腎と透析,50(6):853−856,2001.

31.Twitcherに学ぶ  岡田伸太郎
脳と発達,33(2):107−113,2001.

32.代謝性神経疾患の骨髄移植治療  乾 幸治,今泉益栄※,鈴木康之※,高橋幸利※
脳と発達,33(3):233−237,2001.

33.Fucosidosis  赤木幹弘,乾 幸治
先天異常症候群辞典 (上巻)別冊 日本臨牀 領域別症候群シリーズ,16 :731−732, 2001.

34.Krabbe disease, globoid cell leukodystrophy  乾 幸治
先天異常症候群辞典 (下巻)別冊 日本臨牀 領域別症候群シリーズ,34:56−58,2001.

35.Mannosidosis  酒井規夫
先天異常症候群辞典 (下巻)別冊 日本臨牀 領域別症候群シリーズ,34:135−136,2001.

36.Sialidosis  酒井規夫
先天異常症候群辞典 (下巻)別冊 日本臨牀 領域別症候群シリーズ,34:633−634,2001.

原著(邦文) ↑上へ戻る

1.ステロイドホルモン感受性に関与する遺伝子多型の検討
中島滋郎,田村京子,平井治彦,山藤陽子,島 雅昭
ホルモンと臨床 冬季増刊号 ステロイドホルモン研究の進歩2001,49:87−89,2001.

2.片側小脳半球形成不全患者における体性感覚誘発電位/磁場の検討
柳原恵子,真野利之,今井克美
臨床脳波,43(10):679−683,2001.

3.Magnetoencephalography を用いたてんかん焦点の解析
今井克美
脳と発達,33(2):146−152,2001.

4.突発性発疹の解熱発疹期にけいれんを群発し,ヒトヘルペスウイルス6による脳血管障害の関与が示唆された1例
住本真一※,渡辺康宏※,天羽清子,多屋馨子,山本英彦※,葭井操雄※,西村実保※,新居正甫※
日本小児科学会雑誌,105(5):588−591,2001.

5.低カルシウム血症を主所見とした乳児早期のビタミンD欠乏症 — 母親のビタミンD欠乏の関与 —
島 雅昭,平井治彦,志水信彦,中島滋郎,西村久美,小林めぐみ※,田川哲三,田中能久※,安部治郎※,岡田伸太郎
日本小児科学会雑誌,105(9):964−969,2001.

6.高肺血流による肺高血圧モデルラットの作製:— アンギオテンシン変換酵素阻害剤投与の影響 —
小垣滋豊,佐野哲也,三輪谷隆史,北 知子,松下 享,岡田伸太郎
日本小児循環器学会雑誌,17(1):29−34,2001.

7.一側肺動脈狭窄に対するステント留置後3か月後に肺血流の不均等分布が改善された単心室,BCPS 術後の1症例
北 知子,松下 享,小垣滋豊,三輪谷隆史,石井 円,佐野哲也※,市川 肇※,松田 暉※,岡田伸太郎
日本小児循環器学会雑誌,17(4):602−606,2001.

8.小児に対する国内脳死後心臓移植の1症例
松下 享,北 知子,三輪谷隆史,石井 円,那須野明香,角 由紀子,吉田葉子,岡田伸太郎,鍵崎康治※,市川 肇※,福嶌教偉※,松田 暉
日本小児循環器学会雑誌,17(5−6):738−743,2001.

9.胃食道逆流現象の小児におけるバレット食道の有無の検討
位田 忍,恵谷ゆり,吉村文一※,虫明聡太郎,中山雅弘※,八木 誠※,川原央好※
日本小児栄養消化器病学会雑誌,15(2):83−87,2001.

10.ジーントラップ法を用いた軟骨に特異的なGHおよびIGF-1標的遺伝子の探索
大薗恵一,渡邉美幸※,内橋隆行※,山崎美和※,道上敏美※
第6回Novo Nordisk Growth研究会記録集:36−39,2001.

11.マウス腎におけるビタミンD代謝酵素およびメガリンの発現の検討
山形雅代※,宮内芳輝※,道上敏美※,大薗恵一
第12回腎とビタミンD研究会記録集:6−8,2001.

原著(英文) ↑上へ戻る

1.Discovery of β-Hexosaminidase a deficiency in Tay-Sachs diseases.
Okada S,O'Brien JS※
Adv Genet,44:61−66,2001.

2.Role of advanced glycation end products in adynamic bone disease in patients with diabetic nephropathy.
Yamamoto T※,Ozono K,Miyauchi A※,Kasayama S※,Kojima Y※,Shima M,Okada S
Am J Kidney Dis,38(4):161−164,2001.

3.Loss of the SEDL gene product (Sedlin) causes X-linked spondyloepiphyseal dysplasia tarda:Identification of a molecular defect in a Japanese family.
Matsui Y※,Yasui N※,Ozono K,Yamagata M※,Kawabata H※,Yoshikawa H※
Am J Med Genet,99(4):328−330,2001.

4.Alternative splicing of fibronectin transcripts in osteochondrogenic tumors.
Matsui Y※,Nakata K※,Araki N※,Ozono K,Fujita Y※,Tsumaki N※,Kawabata H※,Yasui N※,Sekiguchi K※,Yoshikawa H3※
Anticancer Res,21(2A):1103−1106,2001.

5.Synthesis and evaluation of A-Ring diastereomers of 1α,25-dihydroxy-22-oxavitamin D3 (OCT).
Hatakeyama S※,Okano T※,Maeyama J※,Esumi T※,Hiyamizu H※,Iwabuchi Y※,Nakagawa K※,Ozono K,Kawase A※,Kubodera N※
Bioorg Med Chem,9(2):403−415,2001.

6.Serum levels of soluble adhesion molecules in stem cell trasnplantation-related complications.
Matsuda Y,Hara J,Osugi Y,Tokimasa S,Fujisaki H,Takai K,Ohta H,Kawa-Ha K※
Bone Marrow Transplant,27(9):977−982,2001.

7.Inverse relationship between human herpesvirus-6 and -7 detection after allogeneic and autologous stem cell transplantation.
Miyoshi H,Tanaka-Taya K,Hara J,Fujisaki H,Matsuda Y,Ohta H,Osugi Y,Okada S,Yamanishi K※
Bone Marrow Transplant,27(10):1065−1070,2001.

8.Foscarnet therapy for ganciclovir-resistant cytomegalovirus retinitis after stem cell trans-plantation: effective monitoring of CMV infection by quantitative analysis of CMV mRNA.
Ohta H,Matsuda Y,Tokimasa S,A Sawada,Kim JY,Sashihara J,Amo K,Miyagawa H,Tanaka-Taya K,Yamamoto S※,Tano Y※,Aono T※,Yamanishi K※,Okada S,Hara J.
Bone Marrow Transplant,27(11):1141−1145,2001.

9.Mutational analysis of MECP2 in Japanese patients with atypical Rett syndrome.
Inui K,Akagi M,Ono J※,Tsukamoto H,Shimono K,Mano T,Imai K,Yamada M,Muramatsu T,Sakai N,Okada S
Brain Dev,23(4):212−215,2001.

10.Receptor activator of NF-kB ligand (RANKL) is a key molecule of osteoclast formation for bone metastasis in a newly-developed model of human neuroblastoma.
Michigami T※,Ihara-Watanabe M※,Yamazaki M※,Ozono K
Cancer Res,61(4):1637−1644,2001.

11.A patient with Shiga toxin-associated homolytic uremic syndrome who developed hyperkalemia in recovery period.
Honda A※,Shima M,Hirai H,Shimizu N,Nakamura K,Nakajima S,Nagai T※,Yamamoto T,Okada S
Clin Exp Nephrol,5:44−46,2001.

12.Sequential measurement of human herpesvirus 6 DNA with polymerase chain reaction method in pediatric living-related liver transplantation.
Hasegawa T※,Kimura T※,Sasaki T※,Okada A※,Tanaka-Taya K,Miyagawa H,Amou K,Mushiake S,Yamanishi K※,Ishikawa S※
Clin Transplant,15(3):208−213,2001.

13.Antagonistic actions in vivo of (23S)-25-dehydro-1a-hydroxyvitamin D3-26, 23-lactone on calcium metabolism induced by 1a, 25-dihydroxyvitamin D3.
Ishizuka S※,Miura D※,Ozono K,Chokki M※,Mimura H※,Norman AW※
Endocrinology,142(1):59−67,2001.

14.Hydroxylases involved in vitamin D metabolism are differentially expressed in murine embryonic kidney:Application of whole mount in situ hybridization.
Yamagata M※,Kimoto A※,Michigami T※,Nakayama M※,Ozono K
Endocrinology,142(7):3223−3230,2001.

15.Hyperintensity of posterior pituitary on MR T1WI in a boy with central diabetes insipidus caused by missense mutation of neurophysin II gene.
Kubota T※,Yamamoto T※,Ozono K,Shimotsuji T※
Endocr J,48(4):459−463,2001.

16.Lack of the Polycomb-group gene rae28 causes maturation arrest at the early B-cell develop-mental stage.
Tokimasa S,Ohta H,Sawada A,Matsuda Y,Kim JY,Nishiguchi S※,Hara J,Takihara Y※
Exp Hematol,29(1):93−103,2001.

17.Hypophosphatemic rickets accompanying McCune-Albright syndrome:evidence that a humoral factor causes hypophosphatemia.
Yamamoto T※,Miyamoto K※,Ozono K,Taketani Y※,Katai K※,Miyauchi A※,Shima M,Yoshikawa H※,Yoh K※, Takeda E※,Okada S
J Bone Miner Metab,19(5):287−95,2001.

18.Transcriptional induction of matrix metalloproteinase-13 (collagenase-3) by 1α,†25-dihydroxyvitamin D3 in mouse osteoblastic MC3T3-E1 cells.
Uchida M※,Shima M,Chikazu D※,Fujieda A※,Obara K※,Suzuki H※,Nagai Y※,Yamato H※,Kawaguchi H※
J Bone Miner Res,16(2):221−220,2001.

19.Th1-type responses mediated spontaneous ileitis in a novel murine model of Crohn's disease.
Kosiewictz MM※,Nast CC※,Krisnan A※,Rivera-Nieves J※,Moskaluk CA※,Matsumoto S※,Kozaiwa K※,Cominelli F※
J Clin Invest,107(6):695−702,2001.

20.Frequent detection of the human herpesvirus 6-specific genomes in the livers of children with various liver diseases.
Ozaki Y,Tajiri H,Tanaka-Taya K,Mushiake S,Kimoto A※,Yamanishi K※,Okada S
J Clin Microbiol,39(6):2173−2177,2001.

21.Conflicting actions of parathyroid hormone-related protein and serum calcium as regulators of 25-hydroxyvitamin D3-1α-hydroxylase expression in a nude rat model of humoral hypercalcemia of malignancy.
Michigami T※,Yamato H※,Suzuki H※,Nagai-Itagaki Y※,Sato K※,Ozono K
J Endocrinol,171(2):249−257,2001.

22.A 13C-urea breath test in children with Helicobacter pylori infection:Assessment of eradication therapy and follow-up after treatment.
Yoshimura N※,Tajiri H,Sawada A,Kozaiwa K,Ida S※,Fujisawa T※,Konno M※,Kato S※
J Gastroenterol,36(9):606−611,2001.

23.A novel acrivating mutation (C129S) in the calcium-sensing receptor gene in a Japanese family with autosomal dominant hypocalcemia.
Hirai H,Nakajima S,Miyauchi A※,Nishimura K,Shimizu N,Shima M,Michigami†T※,Ozono K,Okada S
J Hum Genet,46(1):41−44,2001.

24.A large outbreak of foodborne infection attributed to Providencia alcalifaciens.
Murata T※,Iida T※,Shiomi Y※,Tagomori K※,Akeda Y※,Yanagihara I※,Mushiake S,Ishiguro F※,Honda T※
J Infect Dis,184(8):1050−1055,2001.

25.Three cases with TT virus infection and idiopathic neonatal hepatitis.
Tajiri H,Tanaka T※,Sawada A,Etani Y,Kozaiwa K,Mishiro S※,Mushiake S
J Intervirology,44(6):364−369,2001.

26.A new variant neuropathic type of Gaucher's disease characterized by hydrocephalus, corneal opacities, deformed toes, and fibrous thickening of spleen and liver capsules.
Inui K,Yanagihara K,Otani K※,Suzuki Y※,Akagi M,Nakayama M※,Ida H※,Okada S
J Pediatr,138(1):137−139,2001.

27.Fluorescence in situ hybridization analysis of peripheral blood cells in Pearson marrow-pancreas syndrome.
Yanagihara I※,Inui K,Yanagihara K,Park YD※,Tanaka J※,Ozono K,Okada S,Kurahashi H※
J Pediatr,139(3):452−455,2001.

28.Clinicopathologic relationship of hypoganglionosis.
Kubota A※,Yamauchi K※,Yonekura T※,Kosumi T※,Oyanagi H※,Mushiake S,Nakayama M※,Imura K※,Okada A※
J Pediatr Surg,36(6):898−900,2001.

29.Late recurrence of neuroblastoma stage 4S with unusual clinicopathologic findings.
Kato K※,Ishikawa K※,Toyoda Y※,Kigasawa H※,Aida N※,Nishi T※,Kusafuka T※,Hara J,Ijiri R※,Tanaka Y※
J Pediatr Surg,36(6):953−955,2001.

30.Bidirectional cavopulmonary shunt with right ventricular outflow patency : The impact of pulsatility on pulmonary endothelial function.
Kurotobi S,Sano T,Kogaki S,Matsushita T,Miwatani T,Takeuchi M,Matsuda†H※,Okada S.
J Thorac Cardiovasc Surg,121(6):1161−1168,2001.

31.Intensification of chemotherapy by using block therapies as consolidation and reinduction therapies for acute lymphoblastic leukemia of childhood.
Hara J,Park Y-D※,Yoshioka A※,Yumura-Yagi K※,Koudera K※,Hosoi G※,Sako M※,Kosaka Y※,Sano K※,Misu H※,Mabuchi O※,Aoyagi N※,Yamamoto M※,Tawa A※,Miyata H※,Tanaka H※,Kikkawa M※,Shimodera M※,Kawa-Ha K※
Int J Hematol,74(8):165−172,2001.

32.Intra-arterial high-dose chemotherapy consisting of melphalan and thio-TEPA with stem cell rescue for advanced maxillary tumors.
Osugi Y,Tokimasa S,Fujisaki H,Takai K,Nakanishi K,Matsuda Y,Ohta H,Okada†S,Hara J
Int J Ped Hematol/Oncol,7(2):109−116,2001.

33.Multimodal therapy for primary intracranial nongerminomatous malignant germ cell tumor in children and young adults.
Ohta H,Matsuda Y,Osugi Y,Fujisaki H,Tokimasa S,Maruno M※,Yoshimine T※,Inoue T※,Inoue T※,Hara J
Int J Pediatr Hematol/Oncol,7(5−6):385−390,2001.

34.Prospective study of mother-to-infant transmission of hepatitis C virus.
Tajiri H,Miyoshi Y,Funada S※,Etani Y,Abe J※,Onodera T※,Goto M※,Funato†M※,Ida S※,Noda C※,Nakayama M※,Okada S
Pediatr Infect Dis J,20(1):10−14,2001.

35.Skeletal development of achondroplasia: analysis of genotyped patients.
Matsui Y※,Kawabata H※,Ozono K,Yasui N※
Pediatr Int,43(4):361−363,2001.

36.SSCP analysis by RT-PCR for the prenatal diagnosis of Niemann-Pick disease type C.
Tsukamoto H,Yamamoto T※,Nishigaki T,Sakai N,Nanba E※,Ninomiya H※,Ohno K※,Inui K,Okada S
Prenat Diagn,21(1):55−57,2001.

37.Cytomegalovirus hepatitis confirmed by in Situ Hybridization in 3 lmmunocompetent infants.
Tajiri H,Kozaiwa K,Tanaka-Taya K,Tada K,Takeshima T※,Yamanishi K※
Scand J Infect Dis,33(10):790−793,2001.

38.Differential activities of 1alpha,25-dihydroxy-16-ene-vitamin D(3) analogs and their 3-epimers on human promyelocytic leukemia (HL-60) cell differentiation and apoptosis.
Nakagawa K※,Sowa Y※,Kurobe M※,Ozono K,Siu-Caldera M※,Reddy GS※,Uskokovic MR※,Okano T※
Steroids,66(3−5):327−337,2001.

39.(23S)-and (23R)-25-dehydro-1α-hydroxyvitamin D3-26,23-lactone function as antagonists of vitamin D receptor-mediated genomic actions of 1α,25-dihydroxyvitamin D3.
Ishizuka S※,Miura D※,Ozono K,Saito M※,Eguchi H※,Chokki M※,Norman AW※
Steroids,66(3−5):227−237,2001.

40.Retransplanation Following Graft Failure of Stem Cell transplanation : A Single-Center Experience.
Ohta H,J Kim,Sawada A,Tokimasa S,Fujisaki H,Matsuda Y,Osugi Y,Hara J
Jpn J Pediatr Hematol,15(5):388−395,2001.