Laboratory of Sleep Disorder


Yoshiro Sugita
Professor, M.D., Ph.D
Hiroyoshi Adachi
Assistant Professor, M.D., Ph.D
Takayuki Kumano-go
Lecturer, M.D., Ph.D
Yoshihisa Shigedo
Postdoctoral Fellow, M.D., Ph.D
Nakamori Suganuma
Postgraduate Student (Doctoral Course)
Hiroko Morishima
Postgraduate Student (Doctoral Course), M.D.
Syuhei Yamamura
Postgraduate Student (Doctoral Course), M.D.
Kentaro Yanagi
Postgraduate Student (Doctoral Course), M.D.
Masaharu Kikuchi
Postgraduate Student (Master's Course)

Our research themes

At the sleep laboratory, the work for sleep medicine and sleep medical treatment is set as the center of fundamental activity. Moreover, we are also tackling energetically clinical activity in industrial hygiene and school mental health in Osaka University.

The consulting division of sleep medicine is established 2 days per week at the department of psychiatry in the Osaka University Hospital. Be related with sleep medicine, we have recommended acquiring the qualification of sleep specialists certified by the Japanese Society of Sleep Research. Currently, four sleep specialists are on the register in our laboratory.

As of now, it is going to greet the turning point of the sleep medicine in the Osaka University Hospital, followed on establishment of the sleep medical center from April 1, 2006. Some specialties, such as psychiatry, otolaryngology, and pediatrics, have so far performed sleep medical consultation individually. We plan to unite sleep medical consultation organically and to make it the center which can offer efficient and high quality sleep medical treatment. On a mid- and long-term basis, the medical consultation, the education, the research, and the grant about sleep will become comprehensive in our sleep medical center, and in Japan, it will certainly serve as an institution of a core.

The study meeting is held from 18:30 p.m. on Thursday every week in the laboratory. Please come to participate freely.

Research Projects

  1. Research on the mechanism of the micro arousal reaction and pulse wave change seen in sleep disordered breathing
  2. Research of the nutrient material which brings an effect to sleep improvement
  3. Study about the increase of oxidative stress due to sleep deprivation and anti-oxidative function of sleep
  4. The effect to sleep of gastroesophageal reflux disease (GERD)
  5. The epidemiological study and cohort research of "Presenteeism" in the university student

Recent publications

  • Detection of sleep respiratory disturbance with photoplethysmography
    Suganuma N, Kumano-go T, Matsumoto H, Yamamura S, Morishima H, Adachi H, Mikami A, Sugita Y, Takeda M
    Sleep Medicine, 6 S2: S62, 2005
  • Factors influencing quality of sleep in primary caregivers of patients with Alzheimer's disease
    Adachi H, Tachibana N, Ikeda M, Hokoishi K, Komori K, Fukuhara R, Hyoudou T, Ishikawa T, Mori T, Toyota Y, Matsumoto T, Matsumoto N, Shinagawa S, Mikami A, Tanabe H
    Sleep Medicine, 6 S2: S187-188, 2005
  • Sleep characteristics of menopausal insomnia: a polysomnographic study.
    Terashima K, Mikami A, Tachibana N, Kumano-Go T, Teshima Y, Sugita Y,
    Takeda M.
    Psychiatry and Clinical Neurosciences 58:179-185, 2004
  • Three components of obstructive sleep apnea/hypopnea syndrome
    Kumano-go T, Mikami A, Suganuma N, Adachi H, Watanabe T, Shigedo Y, Sugita Y, Takeda M
    Psychiatry and Clinical Neurosciences 57;197-203, 2003
  • Clinical significance of pulse rate rise during sleep as a screening marker for the assessment of sleep fragmentation in sleep-disordered breathing
    Adachi H, Mikami A, Kumano-go T, Suganuma N, Matsumoto H, Shigedo Y, Sugita Y, Takeda M
    Sleep Medicine 4:537-542, 2003
  • The relationship between esophageal pressure and apnea hypopnea index in obstructive sleep apnea-hypopnea syndrome
    Watanabe T, Kumano-go T, Suganuma N, Shigedo Y, Motonishi M, Honda H, Kyotani K, Uruha S, Terashima K, Teshima Y, Takeda M, Sugita Y
    Sleep Res Online 3;169-172, 2000
  • Esophageal pressure and apnea hypopnea index in sleep-disordered breathing
    Watanabe T, Mikami A, Shigedo Y, Motonishi M, Honda H, Kyotani K, Uruha S, Terashima K, Teshima Y, Sugita Y, Takeda M
    Psychiatry and Clinical Neurosciences 54;338-339, 2000
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