宮崎 雄 特任助教 プロフィール

所属学会

Publication list

Research Articles

  1. Miyazaki Y, Du X, Muramatsu S, Gomez CM, An miRNA-mediated therapy for SCA6 blocks IRES-driven translation of the CACNA1A second cistron. Science Translational Medicine, 8: 347ra94, 2016.
  2. Iida M, Katsuno M, Nakatsuji H, Adachi H, Kondo N, Miyazaki Y, Tohnai G, Ikenaka K, Watanabe H, Yamamoto M, Kishida K, Sobue G. Pioglitazone suppresses neuronal and muscular degeneration caused by polyglutamine-expanded androgen receptors. Human Molecular Genetics, 24: 314-329, 2015.
  3. Ohkawa T, Satake S, Yokoi N, Miyazaki Y, Ohshita T, Sobue G, Takashima H, Watanabe O, Fukata Y, Fukata M. Identification and Characterization of GABAA Receptor Autoantibodies in Autoimmune Encephalitis. Journal of Neuroscience, 34: 8151-8163, 2014.
  4. Tohnai G, Adachi H, Katsuno M, Doi H, Matsumoto S, Kondo N, Miyazaki Y, Iida M, Nakatsuji H, Qiang Q, Ding Y, Watanabe H, Yamamoto M, Ohtsuka K, Sobue G. Paeoniflorin eliminates a mutant AR via NF-YA-dependent proteolysis in spinal and bulbar muscular atrophy. Human Molecular Genetics, 23: 3552-3565, 2014.
  5. Doi H, Adachi H, Katsuno M, Minamiyama M, Matsumoto S, Kondo N, Miyazaki Y, Iida M, Tohnai G, Qiang Q, Tanaka F, Yanagawa T, Warabi E, Ishii T, Sobue G. p62/SQSTM1 differentially removes the toxic mutant androgen receptor via autophagy and inclusion formation in a spinal and bulbar muscular atrophy mouse model. Journal of Neuroscience, 33: 7710-7727, 2013.
  6. Qiang Q, Adachi H, Huang Z, Jiang YM, Katsuno M, Minamiyama M, Doi H, Matsumoto S, Kondo N, Miyazaki Y, Iida M, Tohnai G, Sobue G. Genistein, a natural product derived from soybeans, ameliorates polyglutamine-mediated motor neuron disease. Journal of Neurochemistry, 126: 122-130, 2013.
  7. Kondo N, Katsuno M, Adachi H, Minamiyama M, Doi H, Matsumoto S, Miyazaki Y, Iida M, Tohnai G, Nakatsuji H, Ishigaki S, Fujioka Y, Watanabe H, Tanaka F, Nakai A, Sobue G. Heat shock factor-1 influences pathological lesion distribution of polyglutamine-induced neurodegeneration. Nature Communication, 4: 1405, 2013.
  8. Minamiyama M, Katsuno M, Adachi H, Doi H, Kondo N, Iida M, Ishigaki S, Fujioka Y, Matsumoto S, Miyazaki Y, Tanaka F, Kurihara H, Sobue G. Naratriptan mitigates CGRP1-associated motor neuron degeneration caused by an expanded polyglutamine repeat tract. Nature Medicine, 18: 1531-1538, 2012.
  9. Miyazaki Y, Adachi H, Katsuno M, Minamiyama M, Jiang YM, Huang Z, Doi H, Matsumoto S, Kondo N, Iida M, Tohnai G, Tanaka F, Muramatsu S, Sobue G. Viral delivery of miR-196a ameliorates the SBMA phenotype via the silencing of CELF2. Nature Medicine, 18: 1136-1141, 2012.
  10. Miyazaki Y, Hirayama M, Watanabe H, Usami N, Yokoi K, Watanabe O, Sobue G. Paraneoplastic encephalitis associated with myasthenia gravis and malignant thymoma. Journal of Clinical Neuroscience, 19: 336-338, 2012.
  11. Miyazaki Y, Koike H, Akane A, Shibata Y, Nishiwaki K, Sobue G. Spinal cord stimulation markedly ameliorated refractory neuropathic pain in transthyretin Val30Met familial amyloid polyneuropathy. Amyloid, 18: 87-90, 2011.
  12. Miyazaki Y, Koike H, Ito M, Atsuta N, Watanabe H, Katsuno M, Kusunoki S, Sobue G. Acute superficial sensory neuropathy with generalized anhidrosis, anosmia, and ageusia. Muscle Nerve, 43: 286-288, 2011.
  13. Miyazaki Y, Fukuoka K, Murase T, Yamamori I, Mano K. Abnormal MRI and EEG findings in thyroid storm resulting from Graves' disease. Thyroid, 18: 1131–1132, 2008.
  14. Miyazaki Y, Riku Y, Goto Y, Mano K, Yoshida M, Hashizume Y. VZV vasculopathy associated with myelo-radiculoganglio-meningo-encephalitis: an autopsy case of an immunocompetent 66-year-old male. Journal of the Neurological Sciences, 275: 42-45, 2008.

Japanese Reviews

  1. 宮崎雄, 祖父江元. miRNA搭載ウイルスベクターによる球脊髄性筋萎縮症の治療展望. 神経内科, 79(3): 390–399, 2013.
  2. 宮崎雄, 祖父江元. ウイルスによるmiR-196aの遺伝子導入はCELF2の発現抑制を介し球脊髄性筋萎縮症の表現型を改善する. ライフサイエンス新着論文レビュー, e5060, 2012. [Link]