Gallego A, Hartasánchez DA, Brasó-Vives M, Garcia-Ramallo E, Lopez-Valenzuela M, Baena N, Guitart M, Fernández-Bellon H, Kondova I, Bontrop R, Kawahara Y, Espinosa-Parrilla Y.
RNA editing independently occurs at three mir-376a-1 sites and may compromise the stability of the microRNA hairpin.
Gene, 628; 109-116, 2017.
Uemura Y, Oshima T, Yamamoto M, Reyes CJ, Costa Cruz PH, Shibuya T, *Kawahara Y.
Matrin3 binds directly to intronic pyrimidine-rich sequences and controls alternative splicing. Genes to Cells, 22(9); 785-798, 2017.
Kanemitsu Y, Fujitani M, Fujita Y, Zhang S, Su YQ, Kawahara Y, Yamashita T. The RNA-binding protein MARF1 promotes cortical neurogenesis through its RNase activity domain. Scientific Reports, 7(1); 1155, 2017.
Miyake K, Ohta T, Nakayama H, Doe N, Terao Y, Oiki E, Nagatomo I, Yamashita Y, Abe T, Nishikura K, Kumanogoh A, Hashimoto K, *Kawahara Y. CAPS1 RNA Editing Promotes Dense Core Vesicle Exocytosis. Cell Reports, 17; 2004-2014, 2016.
Li Q, Yokoshi M, Okada H, *Kawahara Y. The cleavage pattern of TDP-43 determines its rate of clearance and cytotoxicity. Nature Communications, 6; 6183, 2015.
Li Q, Uemura Y, *Kawahara Y. Cross-Linking and Immunopresipitation of Nuclear RNA-Binding Proteins. Methods in Molecular Biology,1262; 247-263, 2015.
#Yokoshi M, #Li Q, #Yamamoto M, Okada H, Suzuki Y,*Kawahara Y. Direct binding of Ataxin-2 to distinct elements in 3’UTRs promotes mRNA stability and protein expression. Molecular Cell, 55(2); 186-198, 2014. (#Co-first authors)
Nakahama T, Hanieh H, Nguyen NT, Chinen I, Ripley B, Millrine D, Lee S, Nyati KK, Dubey PK, Chowdhury K, Kawahara Y, Kishimoto T. Aryl hydrocarbon receptor-mediated induction of the miR-132/212 cluster promotes TH17 cell differentiation. Proceedings of the National Academy of Sciences U. S. A., 110(29); 11964-11969, 2013.
Matsumoto S, Sakata Y, Nakatani D, Suna S, Usami M, Hara M, Kitamura T, Hamasaki T, Nanto S, *Kawahara Y, *Komuro I. Circulating p53-responsive microRNAs are predictive indicators of heart failure after acute myocardial infarction. Circulation Research, 113(3); 322-326, 2013. (*Co-corresponding authors)
Matsumoto S, Sakata Y, Nakatani D, Suna S, Mizuno H, Shimizu M, Usami M, Sasaki T, Sato H, Kawahara Y, Hamasaki T, Nanto S, Hori M and Komuro I. A Subset of Circulating MicroRNAs are Predictive for Cardiac Death After Discharge for Acute Myocardial Infarction. Biochemical and Biophysical Research Communications, 2012 427(2); 280-284, 2012.
Kin K, Miyagawa S, Fukushima S, Shirakawa Y, Torikai K, Shimamura K, Kawahara Y, Daimon T, Kuratani T, Sawa Y. Tissue- and plasma-specific microRNA signatures for atherosclerotic abdominal aortic aneurysm. Journal of the American Heart Association, 1; e000745, 2012.
*Kawahara Y. Quantification of adenosine-to-inosine editing of microRNAs using a conventional method. Nature Protocols, 7(7); 1426-1437, 2012.
*Kawahara Y and Mieda-Sato I. TDP-43 promotes microRNA biogenesis as a component of the Drosha and Dicer complexes. Proceedings of the National Academy of Sciences U. S. A., 109 (9); 3347-3352, 2012. (*Corresponding author)
Review Articles & Books
*Kawahara Y, Human diseases caused by germline and somatic abnormalities in microRNA and microRNA-related genes. Congenital Anomalies, 54(1); 12-21, 2014.
Valente L, Kawahara Y, Zinshteyn B, Iizasa H and Nishikura K. Post-transcriptional gene regulation by an Editor: ADAR and its role in RNA Editing. Post-transcriptional gene regulation: RNA processing in eukaryotes. (Ed. Jane Wu) Wiley-VCH book, 41-82, 2013.
Morita T, Hayashi K. Tumor progression is mediated by Thymosin-β4 through a TGFβ/MRTF signaling axis. Molecular Cancer Research, 2018, Epub ahead of print.
Watanabe B, Minami S, Ishida H, Yoshioka R, Nakagawa Y, Morita T, Hayashi K. Stereospecific inhibitory effects of CCG-1423 on the cellular events mediated by Myocardin-Related Transcription Factor A. PLoS One, 10: e0136242, 2015.
Hayashi K, Murai T, Oikawa H, Masuda T, Muehlich S, Prywes R, Morita
T. A novel inhibitory mechanism of MRTF-A/B on the ICAM-1 gene expression in vascular endothelial cells. Scientific Reports, 5: 10627, 2015.
Morita T, Hayashi K. Arp5 is a key regulator of myocardin in smooth muscle cells. Journal of Cell Biology, 204: 683-696, 2014.
Hayashi K, Watanabe B, Nakagawa Y, Minami S, Morita T. RPEL proteins are the molecular targets for CCG-1423, an inhibitor of Rho signaling. PLoS ONE, 9: e89016, 2014.
Morita T, Hayashi K. G-actin sequestering protein thymosin-b4 regulates the activity of myocardin-related transcription factor. Biochemical and Biophysical Research Communications, 437: 331-335, 2013.
Hayashi K, Morita T. Importance of dimer formation of myocardin family members in the regulation of their nuclear export. Cell Structure and Function, 38: 123-134, 2013.
Hayashi K, Morita T. Differences in the nuclear export mechanism between myocardin and myocardin-related transcription factors A. The Journal of Biological Chemistry, 288: 5743-5755, 2013.
Tanokashira D, Morita T, Hayashi K, Mayanagi T, Fukumoto K, Kubota Y, Yamashita T, Sobue K, Glucocorticoid suppresses dendritic spine development mediated by down-regulation of caldesmon expression. Journal of Neuroscience, 32:14583?14591, 2012.