PUBLICATIONS

Kawahara group (2011~)

Research Articles

  1. Gallego A, Hartasánchez DA, Brasó-Vives M, Garcia-Ramallo E, Lopez-Valenzuela M, Baena N, Guitart M, Fernández-Bellon H, Kondova I, Bontrop R, Kawahara Y, Espinosa-Parrilla Y. RNA editing independently occurs at three mir-376a-1 sites and may compromise the stability of the microRNA hairpin. Gene, 628; 109-116, 2017.
  2. Uemura Y, Oshima T, Yamamoto M, Reyes CJ, Costa Cruz PH, Shibuya T, *Kawahara Y. Matrin3 binds directly to intronic pyrimidine-rich sequences and controls alternative splicing. Genes to Cells, 22(9); 785-798, 2017.
  3. Kanemitsu Y, Fujitani M, Fujita Y, Zhang S, Su YQ, Kawahara Y, Yamashita T. The RNA-binding protein MARF1 promotes cortical neurogenesis through its RNase activity domain. Scientific Reports, 7(1); 1155, 2017.
  4. Miyake K, Ohta T, Nakayama H, Doe N, Terao Y, Oiki E, Nagatomo I, Yamashita Y, Abe T, Nishikura K, Kumanogoh A, Hashimoto K, *Kawahara Y. CAPS1 RNA Editing Promotes Dense Core Vesicle Exocytosis. Cell Reports, 17; 2004-2014, 2016. F1000Prime
  5. Li Q, Yokoshi M, Okada H, *Kawahara Y. The cleavage pattern of TDP-43 determines its rate of clearance and cytotoxicity. Nature Communications, 6; 6183, 2015.
  6. Li Q, Uemura Y, *Kawahara Y. Cross-Linking and Immunopresipitation of Nuclear RNA-Binding Proteins. Methods in Molecular Biology,1262; 247-263, 2015.
  7. #Yokoshi M, #Li Q, #Yamamoto M, Okada H, Suzuki Y, *Kawahara Y. Direct binding of Ataxin-2 to distinct elements in 3’UTRs promotes mRNA stability and protein expression. Molecular Cell, 55(2); 186-198, 2014. (#Co-first authors)
  8. Nakahama T, Hanieh H, Nguyen NT, Chinen I, Ripley B, Millrine D, Lee S, Nyati KK, Dubey PK, Chowdhury K, Kawahara Y, Kishimoto T. Aryl hydrocarbon receptor-mediated induction of the miR-132/212 cluster promotes TH17 cell differentiation. Proceedings of the National Academy of Sciences U. S. A., 110(29); 11964-11969, 2013.
  9. Matsumoto S, Sakata Y, Nakatani D, Suna S, Usami M, Hara M, Kitamura T, Hamasaki T, Nanto S, *Kawahara Y, *Komuro I. Circulating p53-responsive microRNAs are predictive indicators of heart failure after acute myocardial infarction. Circulation Research, 113(3); 322-326, 2013. (*Co-corresponding authors)
  10. Matsumoto S, Sakata Y, Nakatani D, Suna S, Mizuno H, Shimizu M, Usami M, Sasaki T, Sato H, Kawahara Y, Hamasaki T, Nanto S, Hori M and Komuro I. A Subset of Circulating MicroRNAs are Predictive for Cardiac Death After Discharge for Acute Myocardial Infarction. Biochemical and Biophysical Research Communications, 2012 427(2); 280-284, 2012.
  11. Kin K, Miyagawa S, Fukushima S, Shirakawa Y, Torikai K, Shimamura K, Kawahara Y, Daimon T, Kuratani T, Sawa Y. Tissue- and plasma-specific microRNA signatures for atherosclerotic abdominal aortic aneurysm. Journal of the American Heart Association, 1; e000745, 2012.
  12. *Kawahara Y. Quantification of adenosine-to-inosine editing of microRNAs using a conventional method. Nature Protocols, 7(7); 1426-1437, 2012.
  13. *Kawahara Y and Mieda-Sato I. TDP-43 promotes microRNA biogenesis as a component of the Drosha and Dicer complexes. Proceedings of the National Academy of Sciences U. S. A., 109 (9); 3347-3352, 2012. (*Corresponding author)

Review Articles & Books

  1. *Kawahara Y, Human diseases caused by germline and somatic abnormalities in microRNA and microRNA-related genes.
    Congenital Anomalies, 54(1); 12-21, 2014.
  2. Valente L, Kawahara Y, Zinshteyn B, Iizasa H and Nishikura K. Post-transcriptional gene regulation by an Editor: ADAR and its role in RNA Editing. Post-transcriptional gene regulation: RNA processing in eukaryotes. (Ed. Jane Wu) Wiley-VCH book, 41-82, 2013.

Japanese Reviews

  1. 河原行郎. CLIP法とその改良法によるタンパク質結合RNAの高解像度解析. 実験医学(別冊), 149-158, 2016.
  2. 三宅浩太郎, 中濱泰祐, 河原行郎. 自己免疫疾患とRNA編集. 実験医学(増刊), 33(20): 3339-3344, 2015.
  3. 河原行郎. 神経疾患をmicroRNAで診断する. Clinical Neuroscience, 33(11): 1302-1304, 2015.
  4. 余越萌, 河原行郎. マイクロRNA. 生体の科学, 66(5): 478-479, 2015.
  5. 河原行郎. 神経変性疾患の発症メカニズムUp-to-Date. BIO Clinica, 30(7): 705-708, 2015.
  6. 余越萌, 河原行郎. RNA代謝異常を介した神経変性疾患の発症病態. ファルマシア, 51(1): 37-41, 2015.
  7. 余越萌, 河原行郎. 神経変性疾患関連タンパク質Ataxin-2は3’非翻訳領域にある特定の配列に直接結合することによって、mRNAの安定性を促進しタンパク質発現を増加させる. 新着論文レビュー, e9044, 2014
  8. 植村有里・河原行郎. RNA代謝と神経変性. Brain Medical, 26(3): 209-215, 2014.
  9. 河原行郎・塩見美喜子. RNA疾患研究の新展開. Medical Science Digest 臨時増刊号 RNA疾患 (河原行郎・塩見美喜子編輯), 40(7): 324-325, 2014.
  10. 河原行郎. ノンコーディングRNAと神経変性疾患. 医学のあゆみ, 247(5): 421-426, 2013.
  11. 河原行郎. 筋萎縮性側索硬化症とRNA結合タンパク質. 領域融合レビュー, 2: e010, 2013.
  12. 余越萌, 河原行郎. microRNAの修飾とその機能. 実験医学(増刊), 31(7): 1124-1131, 2013.
  13. 河原行郎. microRNA. 分子脳血管病. 11(4): 431-434, 2012.
  14. 河原行郎. マイクロRNA. 分子精神医学. 11(3): 172-177, 2011.

Hayashi group (2011~)

Research Articles

  1. Morita T, Hayashi K. Tumor progression is mediated by Thymosin-β4 through a TGFβ/MRTF signaling axis. Molecular Cancer Research, 2018, Epub ahead of print.
  2. Watanabe B, Minami S, Ishida H, Yoshioka R, Nakagawa Y, Morita T, Hayashi K. Stereospecific inhibitory effects of CCG-1423 on the cellular events mediated by Myocardin-Related Transcription Factor A. PLoS One, 10: e0136242, 2015.
  3. Hayashi K, Murai T, Oikawa H, Masuda T, Muehlich S, Prywes R, Morita T. A novel inhibitory mechanism of MRTF-A/B on the ICAM-1 gene expression in vascular endothelial cells. Scientific Reports, 5: 10627, 2015.
  4. Morita T, Hayashi K. Arp5 is a key regulator of myocardin in smooth muscle cells. Journal of Cell Biology, 204: 683-696, 2014.
  5. Hayashi K, Watanabe B, Nakagawa Y, Minami S, Morita T. RPEL proteins are the molecular targets for CCG-1423, an inhibitor of Rho signaling. PLoS ONE, 9: e89016, 2014.
  6. Morita T, Hayashi K. G-actin sequestering protein thymosin-b4 regulates the activity of myocardin-related transcription factor.
    Biochemical and Biophysical Research Communications, 437: 331-335, 2013.
  7. Hayashi K, Morita T. Importance of dimer formation of myocardin family members in the regulation of their nuclear export.
    Cell Structure and Function, 38: 123-134, 2013.
  8. Hayashi K, Morita T. Differences in the nuclear export mechanism between myocardin and myocardin-related transcription factors A. The Journal of Biological Chemistry, 288: 5743-5755, 2013.
  9. Tanokashira D, Morita T, Hayashi K, Mayanagi T, Fukumoto K, Kubota Y, Yamashita T, Sobue K, Glucocorticoid suppresses dendritic spine development mediated by down-regulation of caldesmon expression. Journal of Neuroscience, 32:14583?14591, 2012.