大阪大学大学院医学系研究科 核医学講座 / 大阪大学医学部附属病院 核医学診療科・放射線部 Department of Nuclear Medicine and Tracer Kinetics, Osaka University Graduate School of Medicine
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主要な業績
1994-2000年

2001-2010年

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2001年
  1. Mu X, Hasegawa S, Yoshioka J, Maruyama A, Maruyama K, Paul AK, Yamaguchi H, Morozumi T, Hashimoto K, Kusuoka H, Nishimura T. Clinical value of lung uptake of iodine-123 metaiodobenzylguanidine (MIBG), a myocardial sympathetic nerve imaging agent, in patients with chronic heart failure. Ann Nucl Med. 15:411-416, 2001.
  2. Paul AK, Tatsumi M, Fujino K, Hashikawa K, Nishimura T. Feasibility of a short acquisition protocol for whole-body positron emission tomography with fluorine-18 fluorodeoxyglucose. Eur J Nucl Med. 28:1697-1701, 2001.
  3. Yoshioka J, Kusuoka H, Imahashi K, Hashimoto K, Hori M, Terakawa T, Nishimura T. Troglitazone enhances glucose uptake induced by alpha-adrenoceptor stimulation via phosphatidylinositol 3-kinase in rat heart. Clin Exp Pharmacol Physiol. 28:752-757, 2001.
  4. Imahashi K, Nishimura T, Yoshioka J, Kusuoka H. Role of intracellular Na(+) kinetics in preconditioned rat heart. Circ Res. 88:1176-1182, 2001.
  5. Kaminaga T, Mano T, Ono J, Kusuoka H, Nakamura H, Nishimura T. Proton magnetic resonance spectroscopy of Sjogren-Larsson syndrome heterozygotes. Magn Reson Med. 45:1112-1115, 2001.
  6. Tatsumi M, Kitayama H, Sugahara H, Tokita N, Nakamura H, Kanakura Y, Nishimura T. Whole-body hybrid PET with 18F-FDG in the staging of non-Hodgkin's lymphoma. J Nucl Med. 42:601-608, 2001.
  7. Imahashi K, Yoshioka J, Yamakita T, Yamano S, Kusuoka H, Nishimura T. Type IV phosphodiesterase inhibitor suppresses insulin-dependent myocardial glucose uptake. Clin Exp Pharmacol Physiol. 28:290-291, 2001.
  8. Tokita N, Hasegawa S, Tsujimura E, Yutani K, Izumi T, Nishimura T. Serial changes in 14C-deoxyglucose and 201Tl uptake in autoimmune myocarditis in rats. J Nucl Med. 42:285-91, 2001.
2002年
  1. Paul AK, Tatsumi M, Yutani K, Fujino K, Hashikawa K, Nishimura T. Effects of iterative reconstruction on image contrast and lesion detection in gamma camera coincidence imaging in lung and breast cancers. Nucl Med Commun. 23:103-110, 2002.
  2. Paul AK, Kusuoka H, Hasegawa S, Yonezawa T, Makikawa M, Nishimura T. Prolonged diastolic dysfunction following exercise induced ischaemia: a gated myocardial perfusion SPECT study. Nucl Med Commun. 23:1129-1136, 2002.
  3. Paul AK, Hasegawa S, Yoshioka J, Mu X, Maruyama K, Kusuoka H, Nishimura T. Characteristics of regional myocardial stunning after exercise in gated myocardial SPECT. J Nucl Cardiol. 9:388-394, 2002.
  4. Maruyama A, Hasegawa S, Paul AK, Xiuli M, Yoshioka J, Maruyama K, Hori M, Nishimura T. Myocardial viability assessment with gated SPECT Tc-99m tetrofosmin % wall thickening: comparison with F-18 FDG-PET. Ann Nucl Med. 16:25-32, 2002.
  5. Hasegawa S, Kusuoka H, Maruyama K, Kurosawa H, Tazawa S, Ishida S, Inoue M, Hori M, Nishimura T. Detection of viable myocardium with p-iodophenyl-9-(R,S)-methylpentadecanoic acid in ischemic rat myocardium. J Nucl Cardiol. 9:463-470, 2002.
  6. Hasegawa S, Kusuoka H, Fukuchi K, Yutani K, Maruyama K, Hori M, Nishimura T. 14C-deoxyglucose imaging overestimates myocardial viability in subacute infarction of rats. Nucl Med Commun. 23:209-217, 2002.
  7. Tatsumi M, Tsuruo T, Nishimura T. Evaluation of MS-209, a novel multidrug-resistance-reversing agent, in tumour-bearing mice by technetium-99m-MIBI imaging. Eur J Nucl Med Mol Imaging. 29:288-294, 2002.
  8. Imaizumi M, Kitagawa K, Hashikawa K, Oku N, Teratani T, Takasawa M, Yoshikawa T, Rishu P, Ohtsuki T, Hori M, Matsumoto M, Nishimura T. Detection of misery perfusion with split-dose 123I-iodoamphetamine single-photon emission computed tomography in patients with carotid occlusive diseases. Stroke. 33:2217-2223, 2002.
  9. Kagawa S, Nakano T, Inoue O, Nishimura T. Effect of glutamatergic systems on in vivo binding of [(125)I]beta-CIT in the brain of a rat model of Parkinson's disease. Synapse. 46:38-44, 2002.
  10. Ishikawa M, Hosoi R, Kobayashi K, Nishimura T, Inoue O. Rolipram depresses [(3)H]2-deoxyglucose uptake in mouse brain and heart in vivo. Eur J Nucl Med Mol Imaging. 29:1212-1215, 2002.
  11. Kobayashi K, Hosoi R, Momosaki S, Koike S, Ando K, Nishimura T, Inoue O. Enhancement of the relative uptake of 18F-FDG in mouse fibrosarcoma by rolipram. Ann Nucl Med. 16:507-510, 2002.
  12. Takasawa M, Murase K, Oku N, Kawamata M, Imaizumi M, Yoshikawa T, Osaki Y, Paul AK, Kitagawa K, Matsumoto M, Hori M. Automatic determination of brain perfusion index for measurement of cerebral blood flow using spectral analysis and 99mTc-HMPAO. Eur J Nucl Med Mol Imaging. 29:1443-1446, 2002.
  13. Takasawa M, Kitagawa K, Ohtsuki T, Oku N, Hashikawa K, Sakoda S, Hori M, Matsumoto M. Prominent matched hypoperfusion in an intact cerebellum after a solitary middle cerebellar peduncle infarct. AJNR Am J Neuroradiol. 23:1356-1358, 2002.
  14. Takasawa M, Murase K, Oku N, Yoshikawa T, Osaki Y, Imaizumi M, Matsuzawa H, Fujino K, Hashikawa K, Kitagawa K, Hori M, Matsumoto M. Assessment of acetazolamide reactivity in cerebral blood flow using spectral analysis and technetium-99m hexamethylpropylene amine oxime. J Cereb Blood Flow Metab. 22:1004-1009, 2002.
  15. Takasawa M, Watanabe M, Yamamoto S, Hoshi T, Sasaki T, Hashikawa K, Matsumoto M, Kinoshita N. Prognostic value of subacute crossed cerebellar diaschisis: single-photon emission CT study in patients with middle cerebral artery territory infarct. AJNR Am J Neuroradiol. 23:189-193, 2002.
2003年
  1. Maruyama K, Hasegawa S, Nakatani D, Paul AK, Kusuoka H, Nishimura T, Hori M, Hatazawa J. Left ventricular mass index measured by quantitative gated myocardial SPECT with 99mTc-tetrofosmin: a comparison with echocardiography. Ann Nucl Med. 17:31-39, 2003.
  2. Yoshioka J, Node K, Hasegawa S, Paul AK, Mu X, Maruyama K, Nakatani D, Kitakaze M, Hori M, Nishimura T. Impaired cardiac response to exercise in post-menopausal women: relationship with peripheral vascular function. Nucl Med Commun. 24:383-389, 2003.
  3. Tokita N, Hasegawa S, Maruyama K, Izumi T, Blankenberg FG, Tait JF, Strauss HW, Nishimura T. 99mTc-Hynic-annexin V imaging to evaluate inflammation and apoptosis in rats with autoimmune myocarditis. Eur J Nucl Med Mol Imaging. 30:232-238, 2003.
  4. Takasawa M, Oku N, Osaki Y, Kinoshita H, Imaizumi M, Yoshikawa T, Kimura Y, Kajimoto K, Sasagaki M, Kitagawa K, Hori M, Hatazawa J. Cerebral and cerebellar activation in power and precision grip movements: an H2 15O positron emission tomography study. J Cereb Blood Flow Metab. 23:1378-1382, 2003.
  5. Yoshikawa T, Murase K, Oku N, Imaizumi M, Takasawa M, Rishu P, Kimura Y, Ikejiri Y, Kitagawa K, Hori M, Hatazawa J. Heterogeneity of cerebral blood flow in Alzheimer disease and vascular dementia. AJNR Am J Neuroradiol. 24:1341-1347, 2003.
  6. Takasawa M, Murase K, Oku N, Kawamata M, Nagayoshi M, Osaki Y, Imaizumi M, Yoshikawa T, Kitagawa K, Hori M, Hatazawa J. Interobserver variability of cerebral blood flow measurements obtained using spectral analysis and technetium-99m labeled compounds. Ann Nucl Med. 17:255-259, 2003.
  7. Yoshikawa T, Murase K, Oku N, Kitagawa K, Imaizumi M, Takasawa M, Nishikawa T, Matsumoto M, Hatazawa J, Hori M. Statistical image analysis of cerebral blood flow in vascular dementia with small-vessel disease. J Nucl Med. 44:505-511, 2003.
2004年
  1. Fukuchi K, Tatsumi M, Ishida Y, Oku N, Hatazawa J, Wahl RL. Radionuclide imaging metabolic activity of brown adipose tissue in a patient with pheochromocytoma. Exp Clin Endocrinol Diabetes. 112:601-603, 2004.
  2. Imaizumi M, Kitagawa K, Oku N, Hashikawa K, Takasawa M, Yoshikawa T, Osaki Y, Matsushita K, Matsumoto M, Hori M, Hatazawa J. Clinical significance of cerebrovascular reserve in acetazolamide challenge -comparison with acetazolamide challenge H2O-PET and Gas-PET. Ann Nucl Med. 18:369-374, 2004.
  3. Abe K, Kashiwagi Y, Tokumura M, Hosoi R, Hatazawa J, Inoue O. Discrepancy between cell injury and benzodiazepine receptor binding after transient middle cerebral artery occlusion in rats. Synapse. 53:234-239, 2004.
  4. Hatazawa J, Shimosegawa E, Osaki Y, Ibaraki M, Oku N, Hasegawa S, Nagata K, Hirata Y, Miura Y. Long-term angiotensin-converting enzyme inhibitor perindopril therapy improves cerebral perfusion reserve in patients with previous minor stroke. Stroke. 35:2117-2122, 2004.
  5. Takasawa M, Murase K, Oku N, Kawamata M, Nagayoshi M, Imaizumi M, Yoshikawa T, Osaki Y, Kimura Y, Kajimoto K, Kitagawa K, Hori M, Hatazawa J. Spectral analysis of 99mTc-HMPAO for estimating cerebral blood flow: a comparison with H2(15)O PET. Ann Nucl Med. 18:243-249, 2004.
  6. Rishu P, Oku N, Kitagawa K, Imaizumi M, Matsushita K, Yoshikawa T, Takasawa M, Osaki Y, Kimura Y, Kajimoto K, Hori M, Hatazawa J. Cerebral hemodynamics and metabolism in adult moyamoya disease: comparison of angiographic collateral circulation. Ann Nucl Med. 18:115-121, 2004.
  7. Saitoh Y, Osaki Y, Nishimura H, Hirano S, Kato A, Hashikawa K, Hatazawa J, Yoshimine T. Increased regional cerebral blood flow in the contralateral thalamus after successful motor cortex stimulation in a patient with poststroke pain. J Neurosurg. 100:935-939, 2004.
  8. Murase K, Nagayoshi M, Uenishi Y, Kawamata M, Yamazaki Y, Takasawa M, Oku N, Hatazawa J. Extraction of arterial input function for measurement of brain perfusion index with 99mTc compounds using fuzzy clustering. Nucl Med Commun. 25:299-303, 2004.
  9. Osaki Y, Doi K, Takasawa M, Noda K, Nishimura H, Ihara A, Iwaki T, Imaizumi M, Yoshikawa T, Oku N, Hatazawa J, Kubo T. Cortical processing of tactile language in a postlingually deaf-blind subject. Neuroreport. 15:287-291, 2004.
  10. Ibaraki M, Shimosegawa E, Miura S, Takahashi K, Ito H, Kanno I, Hatazawa J. PET measurements of CBF, OEF, and CMRO2 without arterial sampling in hyperacute ischemic stroke: method and error analysis. Ann Nucl Med. 18:35-44, 2004.
  11. Yoshioka M, Sato T, Furuya T, Shibata S, Andoh H, Asanuma Y, Hatazawa J, Shimosegawa E, Koyama K, Yamamoto Y. Role of positron emission tomography with 2-deoxy-2-[18F]fluoro-D-glucose in evaluating the effects of arterial infusion chemotherapy and radiotherapy on pancreatic cancer. J Gastroenterol. 39:50-55, 2004.
  12. Hosoi R, Okada M, Hatazawa J, Gee A, Inoue O. Effect of astrocytic energy metabolism depressant on 14C-acetate uptake in intact rat brain. J Cereb Blood Flow Metab. 24:188-1890, 2004.
  13. Hasegawa S, Kusuoka H, Maruyama K, Nishimura T, Hori M, Hatazawa J. Myocardial positron emission computed tomographic images obtained with fluorine-18 fluoro-2-deoxyglucose predict the response of idiopathic dilated cardiomyopathy patients to beta-blockers. J Am Coll Cardiol. 43:224-233, 2004.
2005年
  1. Inoue O, Shukuri M, Hosoi R, Amitani M, Matsuura N, Hatazawa J, Takai N. Distinct different intra-tumor distribution of FDG between early phase and late phase in mouse fibrosarcoma. Ann Nucl Med. 19:655-659, 2005.
  2. Nagayoshi M, Murase K, Fujino K, Uenishi Y, Kawamata M, Nakamura Y, Kitamura K, Higuchi I, Oku N, Hatazawa J. Usefulness of noise adaptive non-linear gaussian filter in FDG-PET study. Ann Nucl Med. 19:469-477, 2005.
  3. Osaki Y, Nishimura H, Takasawa M, Imaizumi M, Kawashima T, Iwaki T, Oku N, Hashikawa K, Doi K, Nishimura T, Hatazawa J, Kubo T. Neural mechanism of residual inhibition of tinnitus in cochlear implant users. Neuroreport. 16:1625-1628, 2005.
  4. Natsag J, Tomiyama N, Inoue A, Bryce TJ, Damdinsuren B, Honda O, Mihara N, Sumikawa H, Fujita S, Johkoh T, Hatazawa J, Nakamura H. Pulmonary mucosa-associated lymphoid tissue type lymphoma with increased accumulation of fluorine 18-fluorodeoxyglucose on positron emission tomography. J Comput Assist Tomogr. 29:640-643, 2005.
  5. Sakaguchi M, Kitagawa K, Oku N, Imaizumi M, Yamagami H, Ohtsuki T, Matsushita K, Hougaku H, Matsumoto M, Hatazawa J, Hori M. Critical analysis of hemodynamic insufficiency by head-up tilt in patients with carotid occlusive disease. Circ J. 69:971-975, 2005.
  6. Oku N, Kitagawa K, Imaizumi M, Takasawa M, Piao R, Kimura Y, Kajimoto K, Matsumoto M, Hori M, Hatazawa J. Hemodynamic influences of losartan on the brain in hypertensive patients. Hypertens Res. 28:43-49, 2005.
  7. Fukunaga H, Sekimoto M, Ikeda M, Higuchi I, Yasui M, Seshimo I, Takayama O, Yamamoto H, Ohue M, Tatsumi M, Hatazawa J, Ikenaga M, Nishimura T, Monden M. Fusion image of positron emission tomography and computed tomography for the diagnosis of local recurrence of rectal cancer. Ann Surg Oncol. 12:561-569, 2005.
  8. Hamada K, Myoui A, Ueda T, Higuchi I, Inoue A, Tamai N, Yoshikawa H, Hatazawa J. FDG-PET imaging for chronic expanding hematoma in pelvis with massive bone destruction. Skeletal Radiol. 34:807-811, 2005.
  9. Shimosegawa E, Hatazawa J, Ibaraki M, Toyoshima H, Suzuki A. Metabolic penumbra of acute brain infarctiona correlation with infarct growth. Ann Neurol. 57:495-504, 2005.
  10. Fukuchi K, Tatsumi M, Ishida Y, Oku N, Hatazawa J, Wahl RL. Radionuclide imaging metabolic activity of brown adipose tissue in a patient with pheochromocytoma. Exp Clin Endocrinol Diabetes. 112:601-603, 2005.
  11. Hamada K, Ueda T, Higuchi I, Inoue A, Tamai N, Myoi A, Tomita Y, Aozasa K, Yoshikawa H, Hatazawa J. Peripheral nerve schwannomatwo cases exhibiting increased FDG uptake in early and delayed PET imaging. Skeletal Radiol. 34:52-57, 2005.
2006年
  1. Hamada K, Tomita Y, Ueda T, Enomoto K, Kakunaga S, Myoui A, Higuchi I, Yoshikawa H, Hatazawa J. Evaluation of delayed 18F-FDG PET in differential diagnosis for malignant soft-tissue tumors. Ann Nucl Med. 20:671-675, 2006.
  2. Ansar MA, Osaki Y, Kazui H, Oku N, Takasawa M, Kimura Y, Begum NN, Ikejiri Y, Takeda M, Hatazawa J. Effect of linearization correction on statistical parametric mapping (SPM): a 99mTc-HMPAO brain perfusion SPECT study in mild Alzheimer's disease. Ann Nucl Med. 20:511-517, 2006.
  3. Gu J, Yamamoto H, Fukunaga H, Danno K, Takemasa I, Ikeda M, Tatsumi M, Sekimoto M, Hatazawa J, Nishimura T, Monden M. Correlation of GLUT-1 overexpression, tumor size, and depth of invasion with 18F-2-fluoro-2-deoxy-D-glucose uptake by positron emission tomography in colorectal cancer. Dig Dis Sci. 51:2198-2205, 2006.
  4. Ito H, Sato T, Odagiri H, Inoue K, Shidahara M, Suhara T, Hatazawa J, Fukuda H. Brain and whole body distribution of N-isopropyl-4-iodoamphetamine (I-123) in humans: comparison of radiopharmaceuticals marketed by different companies in Japan. Ann Nucl Med. 20:493-498, 2006.
  5. Osaki Y, Takasawa M, Doi K, Nishimura H, Iwaki T, Imaizumi M, Oku N, Hatazawa J, Kubo T. Auditory and tactile processing in a postmeningitic deaf-blind patient with a cochlear implant. Neurology. 67:887-890, 2006.
  6. Hosoi R, Kashiwagi Y, Hatazawa J, Gee A, Inoue O. Glial metabolic dysfunction caused neural damage by short-term ischemia in brain. Ann Nucl Med. 20:377-380, 2006.
  7. Tsujimura A, Miyagawa Y, Fujita K, Matsuoka Y, Takahashi T, Takao T, Matsumiya K, Osaki Y, Takasawa M, Oku N, Hatazawa J, Kaneko S, Okuyama A. Brain processing of audiovisual sexual stimuli inducing penile erection: a positron emission tomography study. J Urol. 176:679-683, 2006.
  8. Kimura Y, Oku N, Kajimoto K, Katoh H, Tanaka MR, Takasawa M, Imaizumi M, Kitagawa K, Hori M, Hatazawa J. Diastolic blood pressure influences cerebrovascular reactivity measured by means of 123I-iodoamphetamine brain single photon emission computed tomography in medically treated patients with occlusive carotid or middle cerebral artery disease. Ann Nucl Med. 20:209-215, 2006.
  9. Morita S, Oka Y, Tsuboi A, Kawakami M, Maruno M, Izumoto S, Osaki T, Taguchi T, Ueda T, Myoui A, Nishida S, Shirakata T, Ohno S, Oji Y, Aozasa K, Hatazawa J, Udaka K, Yoshikawa H, Yoshimine T, Noguchi S, Kawase I, Nakatsuka S, Sugiyama H, Sakamoto J. A phase I/II trial of a WT1 (Wilms' tumor gene) peptide vaccine in patients with solid malignancy: safety assessment based on the phase I data. Jpn J Clin Oncol. 36:231-236, 2006.
  10. Shinohara T, Nagata K, Yokoyama E, Sato M, Matsuoka S, Kanno I, Hatazawa J, Domino EF. Acute effects of cigarette smoking on global cerebral blood flow in overnight abstinent tobacco smokers. Nicotine Tob Res. 8:113-121, 2006.
  11. Yata K, Suzuki A, Hatazawa J, Shimosegawa E, Nagata K, Sato M, Moroi J. Relationship between cerebral circulatory reserve and oxygen extraction fraction in patients with major cerebral artery occlusive disease: a positron emission tomography study. Stroke. 37:534-536, 2006.
  12. Hamada K, Ueda T, Tomita Y, Yoshikawa H, Hatazawa J. Myoepithelioma of soft tissue originating from the hand: 18F-FDG PET features. AJR Am J Roentgenol. 186:270-271, 2006
  13. Hamada K, Ueda T, Tomita Y, Higuchi I, Inoue A, Tamai N, Myoui A, Aozasa K, Yoshikawa H, Hatazawa J. False positive 18F-FDG PET in an ischial chondroblastoma; an analysis of glucose transporter 1 and hexokinase II expression. Skeletal Radiol. 35:306-310, 2006.
  14. Zoghbi SS, Shetty HU, Ichise M, Fujita M, Imaizumi M, Liow JS, Shah J, Musachio JL, Pike VW, Innis RB. PET imaging of the dopamine transporter with 18F-FECNT: a polar radiometabolite confounds brain radioligand measurements. J Nucl Med. 47:520-527, 2006.
  15. Tanaka C, Ueguchi T, Shimosegawa E, Sasaki N, Johkoh T, Nakamura H, Hatazawa J. Effect of CT acquisition parameters in the detection of subtle hypoattenuation in acute cerebral infarction: a phantom study. AJNR Am J Neuroradiol. 27:40-45, 2006.
2007年
  1. Kanai Y, Hasegawa S, Kimura Y, Oku N, Ito H, Fukuda H, Hatazawa J. N-isopropyl-4-[(123)I]iodoamphetamine ( (123)I-IMP) products: a difference in radiochemical purity, unmetabolized fraction, and octanol extraction fraction in arterial blood and regional brain uptake in rats. Ann Nucl Med. 21:387-391, 2007.
  2. Shimamoto H, Hamada K, Higuchi I, Tsujihata M, Nonomura N, Tomita Y, Okuyama A, Aozasa K, Hatazawa J. Abdominal Tuberculosis: peritoneal involvement shown by F-18 FDG PET. Clin Nucl Med. 32:716-718, 2007.
  3. Hosoi R, Kashiwagi Y, Tokumura M, Abe K, Hatazawa J, Inoue O. Sensitive reduction in 14C-acetate uptake in a short-term ischemic rat brain. J Stroke Cerebrovasc Dis. 16:77-81, 2007.
  4. Kishima H, Saitoh Y, Osaki Y, Nishimura H, Kato A, Hatazawa J, Yoshimine T. Motor cortex stimulation in patients with deafferentation pain: activation of the posterior insula and thalamus. J Neurosurg. 107:43-48, 2007.
  5. Tani N, Saitoh Y, Kishima H, Oshino S, Hatazawa J, Hashikawa K, Yoshimine T. Motor cortex stimulation for levodopa-resistant akinesia: case report. Mov Disord. 22:1645-1649, 2007.
  6. Enomoto K, Hoshida Y, Hamada K, Okada T, Kubo T, Hatazawa J. F-18 FDG PET imaging of cervical tuberculous lymphadenitis. Clin Nucl Med. 32:474-475, 2007.
  7. Miyagawa Y, Tsujimura A, Fujita K, Matsuoka Y, Takahashi T, Takao T, Takada S, Matsumiya K, Osaki Y, Takasawa M, Oku N, Hatazawa J, Kaneko S, Okuyama A. Differential brain processing of audiovisual sexual stimuli in men: comparative positron emission tomography study of the initiation and maintenance of penile erection during sexual arousal. Neuroimage. 36:830-842, 2007.
  8. Kajimoto K, Oku N, Kimura Y, Kato H, Tanaka MR, Kanai Y, Kitagawa K, Maruno M, Yoshimine T, Hori M, Hatazawa J. Crossed cerebellar diaschisis: a positron emission tomography study with L-[methyl-11C]methionine and 2-deoxy-2-[18F]fluoro-D-glucose. Ann Nucl Med. 21:109-113, 2007.
  9. Sasaki T, Kitagawa K, Omura-Matsuoka E, Todo K, Terasaki Y, Sugiura S, Hatazawa J, Yagita Y, Hori M. The phosphodiesterase inhibitor rolipram promotes survival of newborn hippocampal neurons after ischemia. Stroke. 38:1597-1605, 2007.
  10. Hirose S, Umetani Y, Amitani M, Hosoi R, Momosaki S, Hatazawa J, Gee A, Inoue O. Role of NMDA receptors in the increase of glucose metabolism in the rat brain induced by fluorocitrate. Neurosci Lett. 415:259-263, 2007.
  11. Enomoto K, Nakamichi I, Hamada K, Inoue A, Higuchi I, Sekimoto M, Mizuki M, Hoshida Y, Kubo T, Aozasa K, Hatazawa J. Unicentric and multicentric Castleman's disease. Br J Radiol. 80:e24-e26, 2007.
  12. Brown AK, Fujita M, Fujimura Y, Liow JS, Stabin M, Ryu YH, Imaizumi M, Hong J, Pike VW, Innis RB. Radiation dosimetry and biodistribution in monkey and man of 11C-PBR28: a PET radioligand to image inflammation. J Nucl Med. 48:2072-2079, 2007.
  13. Imaizumi M, Briard E, Zoghbi SS, Gourley JP, Hong J, Musachio JL, Gladding R, Pike VW, Innis RB, Fujita M. Kinetic evaluation in nonhuman primates of two new PET ligands for peripheral benzodiazepine receptors in brain. Synapse. 61:595-605, 2007.
  14. Imaizumi M, Kim HJ, Zoghbi SS, Briard E, Hong J, Musachio JL, Ruetzler C, Chuang DM, Pike VW, Innis RB, Fujita M. PET imaging with [11C]PBR28 can localize and quantify upregulated peripheral benzodiazepine receptors associated with cerebral ischemia in rat. Neurosci Lett. 411:200-205, 2007.
  15. Fujita M, Imaizumi M, D'Sa C, Zoghbi SS, Crescenzo MS, Hong J, Musachio JL, Gee AD, Seidel J, Green MV, Pike VW, Duman RS, Innis RB. In vivo and in vitro measurement of brain phosphodiesterase 4 in rats after antidepressant administration. Synapse. 61:78-86, 2007.
  16. Takasawa M, Beech JS, Fryer TD, Hong YT, Hughes JL, Igase K, Jones PS, Smith R, Aigbirhio FI, Menon DK, Clark JC, Baron JC. Imaging of brain hypoxia in permanent and temporary middle cerebral artery occlusion in the rat using 18F-fluoromisonidazole and positron emission tomography: a pilot study. J Cereb Blood Flow Metab. 27:679-689, 2007.
  17. Yamamoto S, Takasawa M, Kajiyama K, Baron JC, Yamaguchi T. Deterioration of hemiparesis after recurrent stroke in the unaffected hemisphere: Three further cases with possible interpretation. Cerebrovasc Dis. 23:35-39, 2007.
2008年
  1. Kimura Y, Kitagawa K, Oku N, Kajimoto K, Kato H, Tanaka M, Sakaguchi M, Hougaku H, Sakoda S, Hatazawa J. Hemodynamic influences of azelnidipine, a novel calcium channel blocker, on cerebral circulation in hypertensive patients with ischemic white matter lesions. Hypertens Res. 31:2147-2154, 2008.
  2. Makino T, Doki Y, Miyata H, Yasuda T, Yamasaki M, Fujiwara Y, Takiguchi S, Higuchi I, Hatazawa J, Monden M. Use of (18)F-fluorodeoxyglucose-positron emission tomography to evaluate responses to neo-adjuvant chemotherapy for primary tumor and lymph node metastasis in esophageal squamous cell carcinoma. Surgery. 144:793-802, 2008.
  3. Isohashi K, Tatsumi M, Higuchi I, Inoue A, Nakajo K, Ishikawa J, Shimosegawa E, Kanakura Y, Nakamura H, Hatazawa J. 18F-FDG-PET in patients with malignant lymphoma having long-term follow-up: staging and restaging, and evaluation of treatment response and recurrence. Ann Nucl Med. 22:795-802, 2008.
  4. Hamada K, Tomita Y, Qiu Y, Zhang B, Ueda T, Myoui A, Higuchi I, Yshikawa H, Aozasa K, Hatazawa J. 18F-FDG-PET of musculoskeletal tumors: a correlation with the expression of glucose transporter 1 and hexokinase II. Ann Nucl Med. 22:699-705, 2008.
  5. Inohara H, Enomoto K, Tomiyama Y, Yoshii T, Osaki Y, Higuchi I, Inoue T, Hatazawa J. The role of CT and (18)F-FDG PET in managing the neck in node-positive head and neck cancer after chemoradiotherapy. Acta Otolaryngol. 7:1-7, 2008.
  6. Kato H, Yoshikawa T, Oku N, Imaizumi M, Takasawa M, Kimura Y, Kajimoto K, Tanaka M, Kitagawa K, Hori M, Hatazawa J. Statistical parametric analysis of cerebral blood flow in vascular dementia with small-vessel disease using Tc-HMPAO SPECT. Cerebrovasc Dis. 26:556-562, 2008.
  7. Shimamoto H, Tatsumi M, Kakimoto N, Hamada S, Shimosegawa E, Murakami S, Furukawa S, Hatazawa J. (18)F-FDG accumulation in the oral cavity is associated with periodontal disease and apical periodontitis: an initial demonstration on PET/CT. Ann Nucl Med. 22:587-593, 2008.
  8. Hasegawa S, Yamamoto K, Sakata Y, Takeda Y, Kajimoto K, Kanai Y, Hori M, Hatazawa J. Effects of cardiac energy efficiency in diastolic heart failure: assessment with positron emission tomography with 11C-acetate. Hypertens Res. 31:1157-1162, 2008.
  9. Tanaka M, Shimosegawa E, Kajimoto K, Kimura Y, Kato H, Oku N, Hori M, Kitagawa K, Hatazawa J. Chronic middle cerebral artery occlusion: a hemodynamic and metabolic study with positron-emission tomography. AJNR Am J Neuroradiol. 29:1841-1846, 2008.
  10. Hayashi T, Suzuki A, Hatazawa J, Hadeishi H, Shirane R, Tominaga T, Yasui N. Post-operative changes of cerebral circulation and metabolism in the acute stage of low-grade aneurysmal subarachnoid hemorrhage. Neurol Res. 30:678-683, 2008.
  11. Higuchi I, Yasuda T, Yano M, Doki Y, Miyata H, Tatsumi M, Fukunaga H, Takiguchi S, Fujiwara Y, Hatazawa J, Monden M. Lack of fludeoxyglucose F 18 uptake in posttreatment positron emission tomography as a significant predictor of survival after subsequent surgery in multimodality treatment for patients with locally advanced esophageal squamous cell carcinoma. J Thorac Cardiovasc Surg. 136:205-212, 212.e1-3, 2008.
  12. Hasegawa Y, Kanai Y, Hasegawa S, Okamoto T, Matsui T, Shimosegawa E, Kurachi Y, Hatazawa J. Evaluation of brain and whole-body pharmacokinetics of 11C-labeled diphenylhydantoin in rats by means of planar positron imaging system. Ann Nucl Med. 22:301-307, 2008.
  13. Enomoto K, Hamada K, Inohara H, Higuchi I, Tomita Y, Kubo T, Hatazawa J. Mucosa-associated lymphoid tissue lymphoma studied with FDG-PET: a comparison with CT and endoscopic findings. Ann Nucl Med. 22:261-267, 2008.
  14. Enomoto K, Inohara H, Higuchi I, Hamada K, Tomiyama Y, Kubo T, Hatazawa J. Prognostic Value of FDG-PET in patients with oropharyngeal carcinoma treated with concurrent chemoradiotherapy. Mol Imaging Biol. 10:224-229, 2008.
  15. Takao T, Tsujimura A, Miyagawa Y, Kiuchi H, Ueda T, Hirai T, Komori K, Takada S, Nonomura N, Osaki Y, Enomoto K, Hatazawa J, Okuyama A. Brain responses during the first desire to void: a positron emission tomography study. Int J Urol. 15:724-728, 2008.
  16. Kato H, Shimosegawa E, Oku N, Kimura Y, Kajimoto K, Tanaka M, Hori M, Kitagawa K, Hatazawa J. Cerebral hemodynamics and oxygen metabolism in patients with moyamoya syndrome associated with atherosclerotic steno-occlusive arterial lesions. Cerebrovasc Dis. 26:9-15, 2008.
  17. Enomoto K, Inohara H, Hamada K, Tamura M, Tomita Y, Kubo T, Hatazawa J. FDG PET imaging of myxofibrosarcoma on the sphenoid sinus. Clin Nucl Med. 33:421-422, 2008.
  18. Izumoto S, Tsuboi A, Oka Y, Suzuki T, Hashiba T, Kagawa N, Hashimoto N, Maruno M, Elisseeva OA, Shirakata T, Kawakami M, Oji Y, Nishida S, Ohno S, Kawase I, Hatazawa J, Nakatsuka S, Aozasa K, Morita S, Sakamoto J, Sugiyama H, Yoshimine T. Phase II clinical trial of Wilms tumor 1 peptide vaccination for patients with recurrent glioblastoma multiforme. J Neurosurg. 108:963-971, 2008.
  19. Kato H, Shimosegawa E, Oku N, Kitagawa K, Kishima H, Saitoh Y, Kato A, Yoshimine T, Hatazawa J. MRI-based correction for partial-volume effect improves detectability of intractable epileptogenic foci on 123I-iomazenil brain SPECT images. J Nucl Med. 49:383-389, 2008.
  20. Amitani M, Ohashi A, Hatazawa J, Gee A, Inoue O. Effect of PK11195 on attenuating the enhancement of glucose utilization induced by quinolinic acid infusion in the rat brain. Synapse. 62:253-258, 2008.
  21. Enomoto K, Nishimura H, Hamada K, Doi K, Kubo T, Hatazawa J. Nuclear imaging of osteoma. Clin Nucl Med. 33:135-136, 2008.
  22. Fujimura Y, Hwang PM, Trout Iii H, Kozloff L, Imaizumi M, Innis RB, Fujita M. Increased peripheral benzodiazepine receptors in arterial plaque of patients with atherosclerosis: An autoradiographic study with [(3)H]PK 11195. Atherosclerosis. 2008 Mar 14. [Epub ahead of print]
  23. Fujita M, Imaizumi M, Zoghbi SS, Fujimura Y, Farris AG, Suhara T, Hong J, Pike VW, Innis RB. Kinetic analysis in healthy humans of a novel positron emission tomography radioligand to image the peripheral benzodiazepine receptor, a potential biomarker for inflammation. Neuroimage. 40:43-52, 2008.
  24. Briard E, Zoghbi SS, Imaizumi M, Gourley JP, Shetty HU, Hong J, Cropley V, Fujita M, Innis RB, Pike VW. Synthesis and evaluation in monkey of two sensitive 11C-labeled aryloxyanilide ligands for imaging brain peripheral benzodiazepine receptors in vivo. J Med Chem. 51:17-30, 2008.
  25. Imaizumi M, Briard E, Zoghbi SS, Gourley JP, Hong J, Fujimura Y, Pike VW, Innis RB, Fujita M. Brain and whole-body imaging in nonhuman primates of [11C]PBR28, a promising PET radioligand for peripheral benzodiazepine receptors. Neuroimage. 39:1289-1298, 2008.
  26. Takasawa M, Moustafa RR, Baron JC. Applications of nitroimidazole in vivo hypoxia imaging in ischemic stroke. Stroke. 39:1629-1637, 2008.
  27. Takasawa M, Jones PS, Guadagno JV, Christensen S, Fryer TD, Harding S, Gillard JH, Williams GB, Aigbirhio FI, Warburton EA, Ostergaard L, Baron JC. How reliable is perfusion MR in acute stroke? Validation and determination of the penumbra threshold against quantitative PET. Stroke. 39:870-877, 2008.
2009年
  1. Yamamoto S, Hatazawa J, ImaizumiM, Shimosegawa E, Aoki M, Sugiyama E, Kawakami M,  Takamatsu S, Minato K, Matsumoto K, Senda M. A Multi-Slice Dual Layer MR-Compatible Animal PET System. IEEE TRANSACTIONS ON NUCLEAR SCIENCE. 2009 Oct; 56(5): 2706-13.
  2. Kitagawa K, Oku N, Kimura Y, Yagita Y, Sakaguchi M, Hatazawa J, Sakoda S. Relationship between cerebral blood flow and later cognitive decline in hypertensive patients with cerebral small vessel disease. Hypertens Res. 2009 Sep;32(9):816-20.
  3. Tsuda H, Aoki T, Oku N, Kimura Y, Hatazawa J, Kinoshita H. Functional brain areas associated with manipulation of a prehensile tool: A PET study. Hum Brain Mapp. 2009 Sep;30(9):2879-89.
  4. Inoue A, Tomiyama N, Tatsumi M, Ikeda N, Okumura M, Shiono H, Inoue M, Higuchi I, Aozasa K, Johkoh T, Nakamura H, Hatazawa J. (18)F-FDG PET for the evaluation of thymic epithelial tumors: Correlation with the World Health Organization classification in addition to dual-time-point imaging. Eur J Nucl Med Mol Imaging. 2009 Aug;36(8):1219-25.
  5. Shimamoto H, Kakimoto N, Fujino K, Hamada S, Shimosegawa E, Murakami S, Furukawa S, Hatazawa J. Metallic artifacts caused by dental metal prostheses on PET images: a PET/CT phantom study using different PET/CT scanners. Ann Nucl Med. 2009 Jul;23(5):443-9.
  6. Imaizumi M, Yamamoto S, Kawakami M, Aoki M, Sugiyama E, Kanai Y, Shimosegawa E, Hatazawa J. Simultaneous imaging of magnetic resonance imaging and positron emission tomography by means of MRI-compatible optic fiber-based PET: a validation study in ex vivo rat brain. Jpn J Radiol. 2009 Jul;27(6):252-6.
  7. Ogura T, Ito H, Hida K, Masuzuka T, Fukuda H, Hatazawa J. Measurement of cerebral blood flow by the autoradiographic method with N-isopropyl-4-[I-123] iodoamphetamine: comparison of radiopharmaceuticals marketed by different companies in Japan. Ann Nucl Med. 2009 Jun;23(4):355-61.
  8. Tatsumi M, Sugahara H, Higuchi I, Fukunaga H, Nakamura H, Kanakura Y, Hatazawa J. Standardized uptake value on FDG-PET as a marker for disease activity in patients with non-Hodgkin's lymphoma: comparison with serum soluble interleukin-2 receptor values. Int J Clin Oncol. 2009 Apr;14(2):150-8.
  9. Kinoshita M, Hashimoto N, Goto T, Yanagisawa T, Okita Y, Kagawa N, Kishima H, Tanaka H, Fujita N, Shimosegawa E, Hatazawa J, Yoshimine T. Use of fractional anisotropy for determination of the cut-off value in 11C-methionine positron emission tomography for glioma. Neuroimage. 2009 Apr 1;45(2):312-8.
  10. Hamada K, Tomita Y, Qiu Y, Tomoeda M, Ueda T, Tamai N, Hashimoto N, Yoshikawa H, Aozasa K, Hatazawa J. (18)F-FDG PET analysis of schwannoma: increase of SUVmax in the delayed scan is correlated with elevated VEGF/VPF expression in the tumors. Skeletal Radiol. 2009 Mar;38(3):261-6.
  11. Hamada K, Tomita Y, Inoue A, Fujimoto T, Hashimoto N, Myoui A, Yoshikawa H, Hatazawa J. Evaluation of chemotherapy response in osteosarcoma with FDG-PET. Ann Nucl Med. 2009 Jan;23(1):89-95.
  12. Itoh T, Abe K, Zoghbi SS, Inoue O, Hong J, Imaizumi M, Pike VW, Innis RB, Fujita M. PET measurement of the in vivo affinity of 11C-(R)-rolipram and the density of its target, phosphodiesterase-4, in the brains of conscious and anesthetized rats. J Nucl Med. 2009 May;50(5):749-56.
  13. Briard E, Zoghbi SS, Simeon FG, Imaizumi M, Gourley JP, Shetty HU, Lu S, Fujita M, Innis RB, Pike VW. Single-step high-yield radiosynthesis and evaluation of a sensitive 18F-labeled ligand for imaging brain peripheral benzodiazepine receptors with pet. J Med Chem. 2009 Feb 12;52(3):688-99.
  14. Tatsumi M, Cohade C, Bristow RE, Wahl RL. Imaging uterine cervical cancer with FDG-PET/CT: direct comparison with PET. Mol Imaging Biol 2009 Jul-Aug;11(4):229-35.

 

2010年
  1. Oku N, Kashiwagi T, Hatazawa J. Nuclear neuroimaging in acute and subacuteischemic stroke. Ann Nucl Med. 2010 Nov;24(9):629-38. Epub 2010 Oct 16.
  2. Takaya M, Kazui H, Tokunaga H, Yoshida T, Kito Y, Wada T, Nomura K, Shimosegawa E, Hatazawa J, Takeda M. Global cerebral hypoperfusion in preclinical stage of idiopathic normal pressure hydrocephalus. J Neurol Sci. 2010 Nov 15;298(1-2):35-41. Epub 2010 Sep 22.
  3. Yamamoto S, Imaizumi M, Watabe T, Watabe H, Kanai Y, Shimosegawa E, Hatazawa J. Development of a Si-PM-based high-resolution PET system for small animals. Phys Med Biol. 2010 Oct 7;55(19):5817-31.
  4. Yamamoto S, Imaizumi M, Shimosegawa E, Hatazawa J. Development of a compact and high spatial resolution gamma camera system using LaBr3(Ce). Nucl. Instr. Meth.-A. Volume 622, Issue 1, 1 October 2010, Pages 261-269
  5. Kimura Y, Siméon FG, Hatazawa J, Mozley PD, Pike VW, Innis RB, Fujita M. Biodistribution and radiation dosimetry of a positron emission tomographic ligand, (18)F-SP203, to image metabotropic glutamate subtype 5 receptors in humans. Eur J Nucl Med Mol Imaging. 2010 Oct;37(10):1943-9.
  6. Yamamoto S, Imaizumi M, Shimosegawa E, Kanai Y, Sakamoto Y, Minato K, Shimizu K, Senda M, Hatazawa J. A compact and high sensitivity positron detector using dual-layer thin GSO scintillators for a small animal PET blood sampling system. Phys Med Biol. 2010 Jul 7;55(13):3813-26.
  7. Makino T, Miyata H, Yamasaki M, Fujiwara Y, Takiguchi S, Nakajima K, Higuchi I, Hatazawa J, Mori M, Doki Y. Utility of response evaluation to neo-adjuvant chemotherapy by (18)F-fluorodeoxyglucose-positron emission tomography in locally advanced esophageal squamous cell carcinoma. Surgery. 2010 Nov;148(5):908-18.
  8. Kimura Y, Kitagawa K, Oku N, Kajimoto K, Kato H, Tanaka M, Sakaguchi M, Hougaku H, Sakoda S, Hatazawa J. Blood pressure lowering with valsartan is associated with maintenance of cerebral blood flow and cerebral perfusion reserve in hypertensive patients with cerebral small vessel disease. J Stroke Cerebrovasc Dis. 2010 Mar;19(2):85-91.
  9. Nakajo K, Tatsumi M, Inoue A, Isohashi K, Higuchi I, Kato H, Imaizumi M, Enomoto T, Shimosegawa E, Kimura T, Hatazawa J. Diagnostic performance of fluorodeoxyglucose positron emission tomography/magnetic resonance imaging fusion images of gynecological malignant tumors: comparison with positron emission tomography/computed tomography. Jpn J Radiol. 2010 Feb;28(2):95-100.
  10. Yamamoto S, Imaizumi M, Kanai Y, Tatsumi M, Aoki M, Sugiyama E, Kawakami M, Shimosegawa E, Hatazawa J. Design and performance from an integrated PET/MRI system for small animals. Ann Nucl Med. 2010 Feb;24(2):89-98.
  11. Koshino K, Watabe H, Hasegawa S, Hayashi T, Hatazawa J, Iida H. Development of motion correction technique for cardiac 15O-water PET study using an optical motion tracking system. Ann Nucl Med. 2010 Jan;24(1):1-11.
  12. Okita Y, Kinoshita M, Goto T, Kagawa N, Kishima H, Shimosegawa E, Hatazawa J, Hashimoto N, Yoshimine T. (11)C-methionine uptake correlates with tumor cell density rather than with microvessel density in glioma: A stereotactic image-histology comparison. Neuroimage. 2010 Feb 15;49(4):2977-82.
  13. Kishima H, Saitoh Y, Oshino S, Hosomi K, Mohamed A, Maruo T, Hirata M, Goto T, Yanagisawa T, Sumitani M, Osaki Y, Hatazawa J, Yoshimine T. Modulation of neuronal activity after spinal cord stimulation for neuropathic pain; H(2)(15)O PET study. Neuroimage. 2010 Feb 1;49(3):2564-9.
  14. Inohara H, Enomoto K, Tomiyama Y, Higuchi I, Inoue T, Hatazawa J. Impact of FDG-PET on Prediction of Clinical Outcome after Concurrent Chemoradiotherapy in Hypopharyngeal Carcinoma. Mol Imaging Biol. 2010 Jan-Feb;12(1):89-97.
  15. Tomimaru Y, Takeda Y, Tatsumi M, Kim T, Kobayashi S, Marubashi S, Eguchi H, Tanemura M, Kitagawa T, Nagano H, Umeshita K, Wakasa K, Doki Y, Mori M. Utility of 2-[18F] fluoro-2-deoxy-D-glucose positron emission tomography in differential diagnosis of benign and malignant intraductal papillary-mucinous neoplasm of the pancreas. Oncol Rep. 2010 Sep;24(3):613-20.
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