{"id":10026,"date":"2026-09-29T11:51:58","date_gmt":"2026-09-29T02:51:58","guid":{"rendered":"https:\/\/www.med.osaka-u.ac.jp\/eng\/?page_id=10026"},"modified":"2026-11-05T13:08:12","modified_gmt":"2026-11-05T04:08:12","slug":"cardiovascular_surgical_technology_innovation","status":"publish","type":"page","link":"https:\/\/www.med.osaka-u.ac.jp\/eng\/introduction\/research\/joint\/cardiovascular_surgical_technology_innovation","title":{"rendered":"Cardiovascular Surgical Technology Innovation"},"content":{"rendered":"<ul class=\"linkBar clearfix\">\n<li><a href=\"https:\/\/www.med.osaka-u.ac.jp\/introduction\/research\/joint\/cardiovascular_surgical_technology_innovation\">Text in Japanese<\/a><\/li>\n<p><!-- <!-- \n\n<li><a href=\"#\" target=\"_blank\" class=\"pdf\" rel=\"noopener\">\u5927\u5b66\u9662\u751f\u5411\u3051\u7814\u7a76\u6982\u8981<\/a><\/li>\n\n --><\/ul>\n<div class=\"index\">\n<div class=\"title\">Advancing cardiovascular surgery through innovation and evidence<\/div>\n<ul>\n<li>Developing minimally invasive endovascular therapies for aortic aneurysms<\/li>\n<li>Expanding endovascular treatment for aortic dissection and optimizing indications<\/li>\n<li>Evaluating stent-graft durability and outcomes beyond 10 years<\/li>\n<li>Investigating the effects of aortic disease and repair on cardiac afterload<\/li>\n<\/ul>\n<\/div>\n<p><!-- \/ .index --><!-- \n\n<div class=\"profile\">\n  \n\n<div class=\"clearfix\">\n    \n\n<div class=\"fl photo\"><img decoding=\"async\" src=\"http:\/\/www.med.osaka-u.ac.jp\/eng\/wp-content\/uploads\/\/introduction\/research\/joint\/immunology_profile.png\" alt=\"\" \/><\/div>\n\n\n    \n\n<div class=\"name\"><span class=\"position\">\u6559\u6388 <\/span>\u6c0f\u540d <\/div>\n\n\n    \n\n<div class=\"member\">\u6240\u5c5e<\/div>\n\n\n    \n\n<div class=\"description\">\u6982\u8981<\/div>\n\n\n  <\/div>\n\n\n<\/div>\n\n --><!-- \/ .profile --><\/p>\n<h3>Innovative Cardiovascular Therapies: Development, Durability, and Hemodynamics<\/h3>\n<p>Advances in medical devices and minimally invasive procedures have expanded treatment options in cardiovascular surgery. Nevertheless, increasingly complex disease and an aging patient population continue to expose the limitations of existing techniques. Our department develops innovative surgical procedures and devices and evaluates their safety, effectiveness, and long-term outcomes through clinical research. Our current work focuses on four interconnected areas of aortic disease.<\/p>\n<p>1. Development of minimally invasive endovascular therapies for aortic aneurysms<br \/>Recent approvals of branched stent-graft systems in Japan have expanded endovascular options for complex aortic aneurysms. However, anatomical requirements and disease-specific indications still exclude many patients. We aim to overcome these limitations by developing new devices and procedural techniques that accommodate a broader range of anatomical configurations and pathologies while maintaining procedural safety.<\/p>\n<p>2. Expanding endovascular treatment for aortic dissection<br \/>Endovascular treatment is increasingly applied to aortic dissection, yet complex anatomy and dissection-specific pathology continue to limit its use. We develop devices and techniques to extend these anatomical boundaries. In parallel, clinical and imaging studies investigate disease progression and aortic remodeling to inform which patients should undergo intervention, when treatment should be performed, and how extensively the aorta should be treated.<\/p>\n<p>3. Assessment of very long-term stent-graft durability<br \/>Our institution was among the early adopters of stent-graft treatment in Japan and has accumulated experience that enables follow-up beyond 10 years. We assess long-term device durability, late complications, changes in aortic morphology, and the need for secondary interventions. These findings will help refine lifelong surveillance and reintervention strategies.<\/p>\n<p>4. Effects of aortic disease and repair on cardiovascular hemodynamics<br \/>The thoracic and abdominal aorta are not merely conduits for blood flow; their elastic properties also buffer pulsatile flow and influence cardiac afterload. Aortic aneurysm and dissection may alter these properties, while open graft replacement and endovascular stent-grafting can further modify vascular mechanics. We investigate changes in aortic stiffness, systemic hemodynamics, and cardiac afterload to assess treatment strategies from a physiological as well as an anatomical perspective.<\/p>\n<p>Across these research areas, we draw on clinical databases and collaborative networks at Osaka University and its affiliated institutions, together with nationwide clinical databases. By integrating device development, multicenter clinical studies, and long-term outcome assessment, we seek to establish evidence-based treatment strategies and advance cardiovascular surgical care.<\/p>\n","protected":false},"excerpt":{"rendered":"<p>Text in Japanese Advancing cardiovascular surgery through innovation and evidence Developing minimally invasiv [&hellip;]<\/p>\n","protected":false},"author":1,"featured_media":0,"parent":91,"menu_order":218,"comment_status":"closed","ping_status":"closed","template":"","meta":{"footnotes":""},"_links":{"self":[{"href":"https:\/\/www.med.osaka-u.ac.jp\/eng\/wp-json\/wp\/v2\/pages\/10026"}],"collection":[{"href":"https:\/\/www.med.osaka-u.ac.jp\/eng\/wp-json\/wp\/v2\/pages"}],"about":[{"href":"https:\/\/www.med.osaka-u.ac.jp\/eng\/wp-json\/wp\/v2\/types\/page"}],"author":[{"embeddable":true,"href":"https:\/\/www.med.osaka-u.ac.jp\/eng\/wp-json\/wp\/v2\/users\/1"}],"replies":[{"embeddable":true,"href":"https:\/\/www.med.osaka-u.ac.jp\/eng\/wp-json\/wp\/v2\/comments?post=10026"}],"version-history":[{"count":3,"href":"https:\/\/www.med.osaka-u.ac.jp\/eng\/wp-json\/wp\/v2\/pages\/10026\/revisions"}],"predecessor-version":[{"id":10280,"href":"https:\/\/www.med.osaka-u.ac.jp\/eng\/wp-json\/wp\/v2\/pages\/10026\/revisions\/10280"}],"up":[{"embeddable":true,"href":"https:\/\/www.med.osaka-u.ac.jp\/eng\/wp-json\/wp\/v2\/pages\/91"}],"wp:attachment":[{"href":"https:\/\/www.med.osaka-u.ac.jp\/eng\/wp-json\/wp\/v2\/media?parent=10026"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}