{"id":3015,"date":"2017-07-25T14:52:45","date_gmt":"2017-07-25T05:52:45","guid":{"rendered":"http:\/\/www.med.osaka-u.ac.jp\/eng\/?p=3015"},"modified":"2017-09-19T11:12:38","modified_gmt":"2017-09-19T02:12:38","slug":"3015","status":"publish","type":"post","link":"https:\/\/www.med.osaka-u.ac.jp\/eng\/archives\/3015","title":{"rendered":"Successful transcatheter treatment of severe cardiac failure, a world first <span><\/span>"},"content":{"rendered":"<p>&nbsp;<\/p>\n<ul class=\"linkBar clearfix\">\n<li><a href=\"http:\/\/www.med.osaka-u.ac.jp\/archives\/8153\">Text in Japanese<\/a><\/li>\n<\/ul>\n<p class=\"figure\"><img loading=\"lazy\" decoding=\"async\" class=\"alignleft size-full wp-image-2959\" src=\"http:\/\/www.med.osaka-u.ac.jp\/eng\/wp-content\/uploads\/2017\/07\/17-2.png\" alt=\"\" width=\"400\" height=\"386\" \/> <\/br><\/br><span class=\"caption\">Figure: Transcatheter biologic valve implantation in the dysfunctional mitral prosthesis.<\/span><\/p>\n<p>2017-07-25<\/p>\n<p>The Cardiovascular Surgery Group at Osaka University performed a transcatheter mitral valve implantation in dysfunctional artificial valves in severe cardiac failure patients with prosthetic valve dysfunction, which was previously thought to be incurable or high-risk, succeeding in improving the cardiac function of these patients. In the future, this technique is anticipated as a new therapy for the treatment of prosthetic valve dysfunction in patients with serious heart failure who are either inoperable or require a post-surgery auxiliary artificial heart.<\/p>\n<p>Led by Professor Yoshiki SAWA, the Cardiovascular Group in the Graduate School of Medicine, Osaka University, has developed a wide variety of treatment for severe heart failure, such as skeletal myoblast cell sheet transplantation. This group has performed over 500 transcatheter valve replacement surgeries, a technique that is gathering attention as minimally invasive heart surgery, establishing Osaka University Hospital\u2019s role as one of Japan\u2019s leading medical institutes.<\/p>\n<p>Cardiac surgery in patients with severe heart failure has been thought to entail a significant risk due to surgical stress. The risk of reoperation is especially high when a prosthetic valve becomes dysfunctional. Also, surgical stress may further deteriorate cardiac function in patients waiting for heart transplants, increasing their need for an auxiliary artificial heart.<\/p>\n<p>This time, Prof. Sawa\u2019s group succeeded in transcatheter mitral valve implantation in patients with severe heart failure in clinical research for transcatheter aortic valve implantation (TAVI), a new therapeutic method which the group had actively performed. Because this therapeutic method has enabled minimally invasive treatment on patients who were previously regarded as being incurable or high-risk, it is highly anticipated as a new treatment method for prosthetic valve dysfunction in patients with severe heart failure.<\/p>\n<p>&nbsp;<\/p>\n<p>Department of Cardiovascular Surgery, Graduate School of Medicine, Osaka University (link in Japanese)<\/p>\n<p>EurekAlert!<\/p>\n<p>AlphaGalileo<\/p>\n<p class=\"figure\"><img loading=\"lazy\" decoding=\"async\" class=\"alignleft size-full wp-image-3029\" src=\"http:\/\/www.med.osaka-u.ac.jp\/eng\/wp-content\/uploads\/2017\/09\/IMG_2651-1024x490.jpg\" alt=\"\" width=\"1024\" height=\"490\" srcset=\"https:\/\/www.med.osaka-u.ac.jp\/eng\/wp-content\/uploads\/2017\/09\/IMG_2651-1024x490.jpg 1024w, https:\/\/www.med.osaka-u.ac.jp\/eng\/wp-content\/uploads\/2017\/09\/IMG_2651-1024x490-400x191.jpg 400w, https:\/\/www.med.osaka-u.ac.jp\/eng\/wp-content\/uploads\/2017\/09\/IMG_2651-1024x490-768x368.jpg 768w\" sizes=\"(max-width: 1024px) 100vw, 1024px\" \/><a href=\"http:\/\/www.med.osaka-u.ac.jp\/eng\/wp-content\/uploads\/\/activities\/results\/2017\/result_2017_article_02_01.jpg\">\u00a0<\/a><\/p>\n","protected":false},"excerpt":{"rendered":"<p>&nbsp; Text in Japanese Figure: Transcatheter biologic valve implantation in the dysfunctional mitral prosthes [&hellip;]<\/p>\n","protected":false},"author":1,"featured_media":2959,"comment_status":"open","ping_status":"open","sticky":false,"template":"","format":"standard","meta":{"footnotes":""},"categories":[1,12],"tags":[],"_links":{"self":[{"href":"https:\/\/www.med.osaka-u.ac.jp\/eng\/wp-json\/wp\/v2\/posts\/3015"}],"collection":[{"href":"https:\/\/www.med.osaka-u.ac.jp\/eng\/wp-json\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/www.med.osaka-u.ac.jp\/eng\/wp-json\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/www.med.osaka-u.ac.jp\/eng\/wp-json\/wp\/v2\/users\/1"}],"replies":[{"embeddable":true,"href":"https:\/\/www.med.osaka-u.ac.jp\/eng\/wp-json\/wp\/v2\/comments?post=3015"}],"version-history":[{"count":11,"href":"https:\/\/www.med.osaka-u.ac.jp\/eng\/wp-json\/wp\/v2\/posts\/3015\/revisions"}],"predecessor-version":[{"id":3028,"href":"https:\/\/www.med.osaka-u.ac.jp\/eng\/wp-json\/wp\/v2\/posts\/3015\/revisions\/3028"}],"wp:featuredmedia":[{"embeddable":true,"href":"https:\/\/www.med.osaka-u.ac.jp\/eng\/wp-json\/wp\/v2\/media\/2959"}],"wp:attachment":[{"href":"https:\/\/www.med.osaka-u.ac.jp\/eng\/wp-json\/wp\/v2\/media?parent=3015"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/www.med.osaka-u.ac.jp\/eng\/wp-json\/wp\/v2\/categories?post=3015"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/www.med.osaka-u.ac.jp\/eng\/wp-json\/wp\/v2\/tags?post=3015"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}