{"id":539,"date":"2025-05-08T11:33:50","date_gmt":"2025-05-08T02:33:50","guid":{"rendered":"https:\/\/www.med.osaka-u.ac.jp\/pub\/anes\/?page_id=539"},"modified":"2025-07-01T13:24:22","modified_gmt":"2025-07-01T04:24:22","slug":"voice08","status":"publish","type":"page","link":"https:\/\/www.med.osaka-u.ac.jp\/pub\/anes\/voice\/voice08","title":{"rendered":"\u5409\u7530 \u5065\u53f2 \u5148\u751f"},"content":{"rendered":"

2012\u5e742\u6708\u304b\u30892013\u5e744\u6708\u307e\u3067Laborat\u00f3rio de Pneumologia LIM\u201309, Disciplina de Pneumologia, Faculdade de Medicina da Universidade de S\u00e3o Paulo\u306b\u7814\u7a76\u7559\u5b66\u3055\u305b\u3066\u3044\u305f\u3060\u304d\u307e\u3057\u305f\u3002\u7559\u5b66\u306e\u7d4c\u7def\u3084\u7559\u5b66\u3067\u5f97\u3089\u308c\u305f\u3053\u3068\u306a\u3069\u3092\u66f8\u3044\u3066\u307f\u305f\u3044\u3068\u601d\u3044\u307e\u3059\u3002<\/p>\n

\u7559\u5b66\u307e\u3067\u306e\u7d4c\u7def<\/h3>\n

2003\u5e74(\u5e73\u621015\u5e74)\u306b\u5352\u696d\u5f8c\u3001\u6025\u6027\u547c\u5438\u4e0d\u5168\u3001\u4e2d\u3067\u3082ARDS (\u6025\u6027\u547c\u5438\u4fc3\u8feb\u75c7\u5019\u7fa4)\u3068\u305d\u308c\u306b\u5bfe\u3059\u308b\u4eba\u5de5\u547c\u5438\u7ba1\u7406\u306e\u5965\u6df1\u3055\u306e\u865c\u306b\u306a\u308b\u3068\u540c\u6642\u306b\u305d\u306e\u6cbb\u7642\u306e\u96e3\u3057\u3055\u3084\u6b7b\u4ea1\u7387\u306e\u9ad8\u3055\u3092\u5b9f\u611f\u3057\u3066\u3044\u307e\u3057\u305f\u3002\u3053\u306e\u73fe\u72b6\u3092\u4f55\u3068\u304b\u6253\u7834\u3057\u305f\u3044\u3068\u3044\u3046\u601d\u3044\u304c\u3001\u3053\u306e\u7814\u7a76\u3092\u59cb\u3081\u3088\u3046\u3068\u601d\u3063\u305f\u304d\u3063\u304b\u3051\u3067\u3057\u305f\u3002\u5927\u962a\u5e9c\u7acb\u547c\u5438\u5668\u30a2\u30ec\u30eb\u30ae\u30fc\u533b\u7642\u30bb\u30f3\u30bf\u30fc\u306e\u77f3\u539f\u82f1\u6a39\u5148\u751f\u3044\u308f\u304f\u300c\u3053\u306e\u7814\u7a76\u3092\u3057\u3066\u3044\u308b\u3068\u3053\u308d\u306f\u5927\u962a\u5927\u5b66\u306e\u96c6\u4e2d\u6cbb\u7642\u90e8\u3057\u304b\u306a\u3044\u300d\u3068\u3044\u3046\u3053\u3068\u3067\u85e4\u91ce\u88d5\u58eb\u5148\u751f\u306b\u3054\u7d39\u4ecb\u9802\u304d\u30012009\u5e744\u6708\u304b\u3089\u9ebb\u9154\u30fb\u96c6\u4e2d\u6cbb\u7642\u533b\u5b66\u8b1b\u5ea7\u3067\u306e\u5927\u5b66\u9662\u751f\u6d3b\u3092\u59cb\u3081\u307e\u3057\u305f\u3002\u5f53\u521d\u306f\u3001\u5b9f\u9a13\u30e2\u30c7\u30eb\u304c\u3046\u307e\u304f\u5b89\u5b9a\u305b\u305a\u306b\u975e\u5e38\u306b\u82e6\u52b4\u3057\u307e\u3057\u305f\u304c\u3001\u60a9\u3093\u3060\u6642\u306b\u306f\u3044\u3064\u3082\u85e4\u91ce\u88d5\u58eb\u5148\u751f\u53ca\u3073\u5185\u5c71\u662d\u5247\u5148\u751f\u304b\u3089\u306e\u9069\u5207\u306a\u30a2\u30c9\u30d0\u30a4\u30b9\u304c\u3042\u3063\u305f\u304b\u3089\u3053\u3053\u307e\u3067\u3084\u3063\u3066\u3053\u3089\u308c\u305f\u3068\u601d\u3044\u307e\u3059\u3002<\/p>\n

\u85e4\u91ce\u88d5\u58eb\u5148\u751f\u304cHarvard\u5927\u5b66\u306b\u7559\u5b66\u3055\u308c\u3066\u3044\u305f\u6642\u304b\u3089\u306e\u77e5\u308a\u5408\u3044\u3067\u3001S\u00e3o Paulo\u5927\u5b66\u306eDr. Marcelo Amato\u3068\u3044\u3046ARDS\/\u4eba\u5de5\u547c\u5438\u7ba1\u7406\u306e\u5206\u91ce\u3067\u4e16\u754c\u7684\u306a\u6a29\u5a01\u306e\u5148\u751f\u304c\u304a\u3089\u308c\u307e\u3059\u3002Dr. Amato\u306fARDS\u306b\u5bfe\u3059\u308b\u4f4e\u4e00\u56de\u63db\u6c17\u91cf\u6cd5\u3092\u63d0\u5531\u3057\u3001\u552f\u4e00ARDS\u306e\u6b7b\u4ea1\u7387\u3092\u4f4e\u4e0b\u3055\u305b\u305f\u4eba\u5de5\u547c\u5438\u7ba1\u7406\u6cd5\u3068\u3057\u3066\u5168\u4e16\u754c\u3067\u8a8d\u77e5\u3055\u308c\u3066\u3044\u307e\u3059(N Engl J Med 1998<\/em>; 338: 347)\u3002\u65e5\u672c\u3067\u958b\u304b\u308c\u305f\u5b66\u4f1a\u306b\u62db\u8058\u3055\u308c\u3001\u305d\u306e\u6642\u306b\u85e4\u91ce\u88d5\u58eb\u5148\u751f\u306b\u521d\u3081\u3066\u7d39\u4ecb\u3057\u3066\u3044\u305f\u3060\u304d\u7559\u5b66\u304c\u6c7a\u307e\u308a\u307e\u3057\u305f\u3002\u5927\u962a\u3067\u4f1a\u98df\u3057\u3066\u3044\u305f\u6642\u306e\u3053\u3068\u3067\u3053\u306e\u591c\u306f\u8208\u596e\u3057\u3066\u306a\u304b\u306a\u304b\u5bdd\u4ed8\u3051\u306a\u304b\u3063\u305f\u3053\u3068\u3092\u899a\u3048\u3066\u3044\u307e\u3059\u3002<\/p>\n

\u30b5\u30f3\u30d1\u30a6\u30ed\u5927\u5b66\u3067\u306e\u7814\u7a76\u751f\u6d3b<\/h3>\n

2012\u5e74\u6e21\u4f2f\u3057\u305f\u6642\u3001\u5927\u962a\u5927\u5b66\u3067\u306f\u5927\u5b66\u9662\u751f3\u5e74\u751f\u3067\u3057\u305f\u3002Sandwich program\u3068\u3044\u3046\u5236\u5ea6\u3067\u30b5\u30f3\u30d1\u30a6\u30ed\u5927\u5b66\u3067\u3082\u5927\u5b66\u9662\u751f\u3068\u3057\u3066Laborat\u00f3rio de Pneumologia LIM\u201309, Disciplina de Pneumologia\u306b\u6240\u5c5e\u3057\u7814\u7a76\u3092\u958b\u59cb\u3057\u307e\u3057\u305f\u3002\u9662\u751f\u306f\u79c1\u3092\u542b\u308110\u540d\u304a\u308a\u3001\u305d\u308c\u4ee5\u5916\u306b\u30da\u30eb\u30fc\u304b\u3089\u306e\u7559\u5b66\u751f\u3084\u30c9\u30a4\u30c4Leipzig\u5927\u5b66\u304b\u3089\u306e\u7559\u5b66\u751f\u3082\u3044\u307e\u3057\u305f\u3002\u5b9f\u9a13\u306f\u8c5a\u306eARDS\u30e2\u30c7\u30eb\u3092\u4f5c\u6210\u3057\u3001CT\u53ca\u3073EIT (electrical impedance tomography)\u3068\u3044\u3063\u305f\u6700\u65b0\u753b\u50cf\u5206\u6790\u88c5\u7f6e\u3092\u7528\u3044\u3066\u5b9f\u9a13\u3092\u884c\u3044\u307e\u3059\u3002EIT\u88c5\u7f6e\u306fDr. Amato\u304c\u958b\u767a\u3055\u308c\u305f\u3082\u306e\u3067\u3001\u80f8\u90e8\u306b32\u6975\u306e\u96fb\u6975\u30d9\u30eb\u30c8\u3092\u5dfb\u3044\u3066\u5c0f\u3055\u306a\u96fb\u6d41\u3092\u6d41\u3057\u96fb\u5727\u306e\u5909\u5316\u3092\u8a18\u9332\u3059\u308b\u3053\u3068\u3067\u3001\u653e\u5c04\u7dda\u88ab\u7206\u306a\u3057\u306b\u30d9\u30c3\u30c9\u30b5\u30a4\u30c9\u3067\u80ba\u306e\u63db\u6c17\u5206\u5e03\u3092\u547c\u5438\u6bce\u306b\u89e3\u6790\u3067\u304d\u308b\u753b\u671f\u7684\u306a\u88c5\u7f6e\u3067\u3059\u3002<\/p>\n

\u5e78\u904b\u306a\u3053\u3068\u306b\u3001\u7814\u7a76\u30c6\u30fc\u30de\u306f\u5927\u962a\u5927\u5b66\u3067\u884c\u3063\u3066\u3044\u305f\u300c\u4eba\u5de5\u547c\u5438\u7ba1\u7406\u4e2d\u306b\u81ea\u767a\u547c\u5438\u304c\u50b7\u5bb3\u80ba\u306b\u4e0e\u3048\u308b\u5f71\u97ff\u300d\u3092\u5f15\u304d\u7d9a\u304d\u884c\u308f\u305b\u3066\u3044\u305f\u3060\u304d\u307e\u3057\u305f\u30022012\u5e744\u670818\u65e5\u3001\u79c1\u306e\u5b9f\u9a13\u30ce\u30fc\u30c8\u306b\u3053\u3046\u66f8\u3044\u3066\u3042\u308a\u307e\u3059\u3001\u5927\u767a\u898b!! \u3053\u306e\u65e5\u306f\u304a\u305d\u3089\u304f\u4e00\u751f\u5fd8\u308c\u308b\u3053\u3068\u304c\u306a\u3044\u3067\u3057\u3087\u3046\u3001Dr. Amato\u542b\u3081\u30e9\u30dc\u306e\u4ef2\u9593\u3068\u5927\u6b53\u58f0\u3092\u3042\u3052\u3066\u65b0\u3057\u3044\u767a\u898b\u306b\u9a5a\u3044\u305f\u65e5\u3067\u3057\u305f\u3002\u80ba\u5185\u5c40\u6240\u306e\u7a7a\u6c17\u306e\u52d5\u304d\u3092real time\u306b\u6349\u3048\u308b\u3053\u3068\u306f\u4eca\u307e\u3067\u4e0d\u53ef\u80fd\u3067\u3057\u305f\u304c\u3001\u4eca\u56deEIT\u3092\u7528\u3044\u308b\u3053\u3068\u3067\u3001ARDS\u306e\u4eba\u5de5\u547c\u5438\u7ba1\u7406\u4e2d\u306b\u81ea\u767a\u547c\u5438\u3092\u6e29\u5b58\u3059\u308b\u3068\u6a2a\u9694\u819c\u306e\u53ce\u7e2e\u3068\u540c\u6642\u306b\u8179\u5074\u80ba\u304cdeflate\u3057\u80cc\u5074\u80ba\u3078\u7a7a\u6c17\u304c\u79fb\u52d5\u3059\u308b\u3068\u3044\u3046Pendelluft\u73fe\u8c61\u3092\u767a\u898b\u3057\u305f\u306e\u3067\u3059\u3002\u3053\u308c\u306f\u5f93\u6765\u306e\u80ba\u751f\u7406\u5b66\u304b\u3089\u306f\u60f3\u50cf\u3067\u304d\u306a\u3044\u5168\u304f\u65b0\u3057\u3044\u767a\u898b\u3067\u3057\u305f\u3002ARDS\u306b\u5bfe\u3059\u308b\u4eba\u5de5\u547c\u5438\u7ba1\u7406\u306f\u4e0a\u8ff0\u306e\u901a\u308a\u3001\u4f4e\u4e00\u56de\u63db\u6c17\u91cf\u6cd5\u3068\u3044\u3046\u80ba\u4fdd\u8b77\u63db\u6c17\u6226\u7565\u3092\u884c\u3044\u3001\u4e00\u56de\u63db\u6c17\u91cf\u306f6ml\/kg\u306b\u5236\u9650\u3057\u307e\u3059\u3002\u3057\u304b\u3057\u3001\u81ea\u767a\u547c\u5438\u3092\u6e29\u5b58\u3059\u308b\u3068\u3001\u305f\u3068\u3048\u4e00\u56de\u63db\u6c17\u91cf\u3092\u5236\u9650\u3057\u3066\u3044\u305f\u3068\u3057\u3066\u3082\u3001Pendelluft\u73fe\u8c61\u306e\u305f\u3081\u306b\u5c40\u6240\u7684\u306b(\u80cc\u5074\u80ba\u9818\u57df)\u304c\u904e\u4f38\u5c55\u3055\u308c\u308b\u3053\u3068\u304c\u660e\u3089\u304b\u306b\u306a\u308a\u3001\u7d50\u679cAm J Respir Crit Care Med<\/em>\u3068\u3044\u3046\u6a29\u5a01\u3042\u308b\u96d1\u8a8c\u306bpublish\u3067\u304d\u307e\u3057\u305f\u3002<\/p>\n

\u7814\u7a76\u751f\u6d3b\u306b\u95a2\u3057\u3066\u3067\u3059\u304c\u3001\u6bce\u9031\u91d1\u66dc\u65e5\u306f\u5b9f\u9a13\u5ba4\u306e\u6e05\u6383\u304c\u5165\u308b\u305f\u3081\u306b\u3001\u5b9f\u969b\u306b\u5b9f\u9a13\u3067\u304d\u308b\u65e5\u306f\u90314\u65e5\u3057\u304b\u3042\u308a\u307e\u305b\u3093\u3002\u307e\u305a\u3001\u3053\u306e\u9650\u3089\u308c\u305f\u5b9f\u9a13\u65e5\u3092\u3044\u304b\u306b\u81ea\u5206\u306e\u3082\u306e\u306b\u3059\u308b\u304b\u306b\u5927\u5909\u306a\u52b4\u529b\u3092\u6ce8\u304e\u307e\u3057\u305f\u3002\u307e\u305f\u8c5a\u3092\u4f7f\u3063\u305f\u5b9f\u9a13\u306f\u3001\u975e\u5e38\u306b\u5927\u639b\u304b\u308a\u3067\u4e00\u56de\u306e\u5b9f\u9a13\u306b\u306f\u6700\u4f4e4\uff5e5\u4eba\u306f\u5fc5\u8981\u3067\u3059\u3002\u671d8\u6642\u304b\u3089\u958b\u59cb\u3059\u308b\u3068\u3001\u307e\u305a\u6c17\u7ba1\u5207\u958b\u3001\u5404\u7a2e\u30e9\u30a4\u30f3\u78ba\u4fdd\u3001EIT\u3084\u6e2c\u5b9a\u6a5f\u5668\u306e\u30bb\u30c3\u30c8\u30a2\u30c3\u30d7\u306a\u3069\u306e\u6e96\u5099\u306b11\u6642\u307e\u3067\u304b\u304b\u308a\u307e\u3059\u3002\u6b21\u306b\u3001ARDS\u30e2\u30c7\u30eb\u4f5c\u6210\u304c\u7d42\u4e86\u3059\u308b\u306e\u306f16\u6642\u3001\u305d\u3053\u304b\u3089CT\u5ba4\u306b\u5927\u79fb\u52d5\u304c\u59cb\u307e\u308a\u3001\u5b9f\u969bCT\u5ba4\u3067\u5b9f\u9a13\u304c\u958b\u59cb\u3067\u304d\u308b\u306e\u306f17\u6642\u9803\u304b\u3089\u306b\u306a\u308a\u307e\u3059\u3002\u7d50\u5c40\u5b9f\u9a13\u304c\u7d42\u4e86\u3059\u308b\u306e\u306f2\uff5e3\u6642\u306b\u306a\u308a\u307e\u3059\u3002\u7fcc\u65e5\u3001\u305d\u306e\u7d50\u679c\u3092\u307e\u3068\u3081\u3066\u3001discussion\u3068\u3044\u3046\u306e\u304c\u4e00\u9023\u306e\u6d41\u308c\u3067\u3059\u3002Dr. Amato\u306f\u6c7a\u3057\u3066\u7d50\u8ad6\u3092\u6025\u304e\u307e\u305b\u3093\u3001\u5f97\u3089\u308c\u305f\u7d50\u679c\u306f\u5fc5\u305a\u591a\u89d2\u7684\u306b\u691c\u8a3c\u3057\u3001\u78ba\u4fe1\u304c\u6301\u3066\u308b\u307e\u3067\u8ffd\u6c42\u3057\u3066\u3044\u304d\u307e\u3059\u3002\u3053\u3046\u3057\u305f\u7d50\u679c\u306b\u5bfe\u3059\u308b\u8003\u5bdf\u306e\u4ed5\u65b9\u306f\u3053\u306e\u7559\u5b66\u4e2d\u3067\u6700\u3082\u52c9\u5f37\u306b\u306a\u3063\u305f\u3082\u306e\u3067\u3001\u79c1\u306e\u7814\u7a76\u306b\u5bfe\u3059\u308b\u8003\u3048\u65b9\u306b\u975e\u5e38\u306b\u5927\u304d\u306a\u5f71\u97ff\u3092\u4e0e\u3048\u307e\u3057\u305f\u3002<\/p>\n

\u7559\u5b66\u3067\u5f97\u3089\u308c\u305f\u3082\u306e<\/h3>\n

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\nTakeshi!<\/em>
\nIt is not every day that we open the email with such great news…<\/em>
\nThe taste was even better after such long battle to get this conceptual paper understood.<\/em>
\nYou are extremely happy – and I’m extremely grateful.<\/em>
\nI’m grateful to Japan, your supporters and sponsors, and your working colleagues for making a tremendous effort and sacrifice to have such smart researcher in our Lab.<\/em>[<\/em>\u4e2d\u7565<\/em>]<\/em>
\nI’m grateful to all the people working in our Lab and Department for the discussions, good will and "physical" support to these long lasting experiments, full of calibration and surgical challenges for our untrained hands.<\/em>
\nFinally, I’m immensely grateful for your mindless decision of coming and joining us in S\u00e3o Paulo for one entire year!<\/em>
\nAs a punishment for this irresponsible attitude, we will have a celebration in Sujinho-<\/em>
\n.. and we must have online conversation with you from there!<\/em>
\nthe Lab (and Sujinho) is waiting for your next visit.<\/em>
\nCongratulations again,<\/em>
\nMarcelo<\/em>\n<\/div>\n

\u3053\u308c\u306f\u3001\u8ad6\u6587\u304caccept\u3055\u308c\u305f\u6642\u306eDr. Amato\u304b\u3089\u306e\u30e1\u30fc\u30eb\u3067\u3059\u3002\u3053\u306e\u30e1\u30fc\u30eb\u3067\u79c1\u306e\u7559\u5b66\u4e2d\u306e\u82e6\u52b4\u306f\u3059\u3079\u3066\u5831\u308f\u308c\u307e\u3057\u305f\u3002<\/p>\n

\u6700\u5f8c\u306b<\/h3>\n

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