6F0604, 0912B6F0613A, 0911BResponsible DepartmentDepartment of Neuro-Medical ScienceResearch PartnerMitsubishi Tanabe Pharma CorporationResponsible DepartmentDepartment of Cutaneous Immunology and MicrobiologyResearch PartnerROHTO Pharmaceutical Co., Ltd.3030• Search for biomarkers of the state of refractory neurological diseases and effect of drug treatment• Basic research on drug development for refractory neurological diseases• Search for new drug targets in refractory neurological diseasesFrustratingly, little is known about the causes of many neurological diseases and little is available in terms of treatment. In this course, we examine the pathology of several neurological diseases, the use of animal models to study the disease, and consider potential drug targets and biomarkers. Studies involve basic and clinical research.Our skin, the largest organ in the human body, protects us from the outside world. It also contains a diverse range of microorganisms that can impact our health. In particular, dysbiosis, which disrupts the normal bacterial flora, is known to occur in diseases such as acne vulgaris, atopic dermatitis, and psoriasis. However, the precise mechanism by which skin microorganisms affect the host's health and diseases is not well understood, and elucidating this could lead to the development of new treatments and preventative measures for skin diseases. Our laboratory employs cutting-edge analytical methods for the skin microbiome and host immunity, as well as 3D skin devices created from induced pluripotent stem cells, to analyze various inflammatory skin diseases and reveal new disease mechanisms, while also working on controlling pre-disease states to achieve "healthy skin."A-21A-29YAMASHITA ToshihideProfessorDepartment of Molecular NeuroscienceFUJIMOTO ManabuProfessorDepartment of DermatologyITOKAZU TakahideSpecially Appointed ProfessorDepartment of Neuro-Medical ScienceMATSUOKA YuumiProfessorImmunology Frontier Research Center (IFReC)New drugs for refractory neurological diseases through translational research1. Understanding the pathogenesis of inflammatory skin diseases associated with dysbiosis2. Analysis of the impact of maintaining skin homeostasis on overall health span
元のページ ../index.html#31