6F7FResponsible DepartmentDepartment of Advanced Hybrid MedicineResearch PartnerTSUMURA & CO.Responsible DepartmentDepartment of Ocular Immunology and Regenerative MedicineResearch PartnerOtsuka Pharmaceutical Co., Ltd.313106140704Our approach combines advanced medicine and traditional medicine, leveraging various intellectual property developed through hybrid medicine. We are working on the social implementation of a new form of hybrid medicine to solve the challenges of frailty, a declining birthrate, and cancer in a super-aged society. Currently, Japan is facing the issues of frailty, a declining birthrate, and an increasing number of cancer patients. In our efforts, we are developing a novel frailty evaluation method called the Japan Frailty Scale (JFS). We are also investigating the molecular mechanisms and building clinical evidence to demonstrate the anti-frailty effects of Go-sha-jinki-Gan (GJG). Additionally, the remarkable clinical outcomes of ketogenic diet for cancer patients have garnered significant attention. As a common mechanism for these problems, we are focused on developing methods to evaluate and enhance resilience.In Japan, retinitis pigmentosa, diabetic retinopathy, and age-related macular degeneration, all of which affect the retina, account for more than 30% of the cause of visual impairment. While chronic inflammation deteriorates pathological condition in these retinal diseases, the molecular mechanisms regulating disease progression have not been fully elucidated. Our goal of the project is to develop novel therapies for resolving chronic inflammation. We attempt drug discovery approach under physiological conditions close to human organs using the animal model and organoid of specific eye diseases based on the research achievements of Ophthalmology at Osaka University.A-13A-6EGASHIRA RyuichiroSpecially Appointed Assistant ProfessorDepartment of Advanced Hybrid MedicineNISHIDA KohjiProfessorDepartment of OphthalmologyHAGIHARA KeisukeGuest ProfessorDepartment of Advanced Hybrid MedicineWe aim to address the challenges of frailty, declining birthrate, and cancer through the application of hybrid medicineElucidation of the involvement of chronic inflammation during the pathogenic processes of various ophthalmic diseases and the creation of treatments
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