9F9F0911AResponsible DepartmentDepartment of Sports Medical ScienceResearch PartnerSaraya Co., Ltd.Responsible DepartmentDepartment of Post-infectious diseases TherapeuticsResearch PartnerShionogi & Co., Ltd.37370901Sports are important in that they contribute to both health and longevity by improving physical activity, and musculoskeletal regenerative medicine, which plays a fundamental role in sports activities, is currently being conducted worldwide from basic research to bridging practical application research, the true outcome of which is to obtain health maintenance through improved physical activity. However, research on prevention of musculoskeletal diseases from the viewpoint of social contribution to physical activity is still in its infancy. The purpose of this cooperative research program is to integrate basic research on muscles, bone and cartilage, nerves, and other musculoskeletal organs important for health maintenance with research on prevention of musculoskeletal diseases, and to develop it into a new medical research field for social implementation.Some patients who have recovered from the acute phase of COVID-19 infection are experiencing various post-infection symptoms called Long COVID, such as respiratory and cardiovascular symptoms, taste and smell disorders, and neurological impairments, leading to a decreased quality of life (QOL) and impact on social life. The pathophysiology of these conditions is largely unknown, and there are no confirmed treatments or prevention methods. Shionogi Pharmaceutical is developing Ensitrelvir fumarate, a new oral antiviral drug that inhibits the 3C-like protease essential for the replication of SARS-CoV-2. This drug has the potential to address these social issues. Universities, with their specialized knowledge and medical infrastructure, are collaborating with industry to rapidly advance research aimed at elucidating the pathophysiology of Long COVID and establishing treatment and prevention methods.A-17A-32NAKATA KenProfessorDepartment of Medicine for Sports and Performing ArtsKUTSUNA SatoshiProfessorDepartment of Infection Control and PreventionTANAKA HiroyukiSpecially Appointed ProfessorDepartment of Sports Medical ScienceONOZUKA DaisukeSpecially Appointed Associate ProfessorDepartment of Post-infectious diseases TherapeuticsResearch and development of social implementation on health maintenance by integration of musculoskeletal regenerative medicine and sports/health epidemiologyResearch Evaluation of Safety and Impact in Long COVID Intervention with Ensitrelvir for National Cohort Efficacy (RESILIENCE study)
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