2014年11月7日から11日にかけてアメリカ・ボストンで開催された、第65回米国肝臓学会総会(The 65th Annual Meeting of the American Association for the Study of Liver Diseases)に参加し、当科の研究成果を発表しました。
　阪大消化器内科からの参加者に加えて阪大消化器内科関連病院からも多数の先生方が参加されました。

　国際学会参加を通じて世界最先端の臨床、研究にふれ、また世界第一線で活躍する臨床家、研究者と直接コンタクトをとることもできるため、非常に良い経験を得ることができました。今回の学会で得た知見を今後の臨床・研究の場に生かしていきたいと思います。

阪大消化器内科からの発表は以下の通りです。

〈Oral Presentation〉
Kunimaro Furuta: "Loss of Grb2-associated binder 1 results in enhanced hepatocyte necrosis and high mortality in mice with acute liver failure."

〈Poster Presentation〉
Yuichi Yoshida: "Grb2-associated binder 1 protects against liver fibrosis via suppression of CCL5 production from hepatocytes." (Presidential Poster of Distinction)

Yoshihiro Kamada: "Fetuin-A negatively correlates with liver and vascular fibrosis in NAFLD subjects."

Yuki Makino: "Impact of connective tissue growth factor in Ras pathway-activated hepatocytes on the development of hepatocellular carcinoma."

Hayato Hikita: "Activation of mitochondrial pathway of apoptosis in hepatocytes increases oxidative stress in hepatocytes leading to liver tumorigenesis."

Yuki Tahata: "The impact of an inosine triphosphatase polymorphism on bilirubin increases in patients with hepatitis C virus infection treated with simeprevir, pegylated interferon plus ribavirin."

Naoki Harada: "Evaluation of liver fibrosis by acoustic radiation force impulse (ARFI) imaging in hemodialysis patients with chronic hepatitis C."

Naoki Morishita: "Ultra-deep sequencing analysis of resistant variants in chronic hepatitis C patients treated with simeprevir, peginterferon and ribavirin."

Tsugiko Oze: "Factors associated with virologic response in triple therapy with simeprevir, pegylated interferon and ribavirin in Japanese patients with chronic hepatitis C."

Kaori Mukai: "Involvement of CXCL1-S100A8 loop via CXCR2 in the development of nonalcoholic fatty liver disease." (Presidential Poster of Distinction)

Satoshi Tanaka: "Increased expression of Rubicon by high fat diet suppresses autophagic flux and induces apoptosis by increasing endoplasmic reticulum stress in mice: a possible mechanism for pathogenesis of NASH." (Presidential Poster of Distinction)

Yoshiki Onishi: "The combined use of sorafenib and branched chain amino acids enhances antitumor effect in the treatment of hepatocellular carcinoma."

Satoshi Aono: "Induction of hepatitis B virus-specific immune responses in immunologically humanized mice." (Presidential Poster of Distinction)

Teppei Yoshioka: "Frequency and role of NKp46 and NKG2A expressing NK cells in patients with chronic hepatitis B."

Yoshinobu Yokoyama: "Immune system is required for HBV clearance, but not enough for explaining the difference in HBV genotype A and C clearance."

Takatoshi Nawa: "Involvement of hepatitis C virus infection in the regulation of chemo-sensitivity of hepatocellular carcinoma cells."

Akira Nishio: "Monocytes-derived Galectin-9 induces the cytotoxixcity of NK cells in chronic hepatitis C."

Ryoko Yamada: "On-treatment alpha-fetoprotein levels have a strong association with hepatocellular carcinoma development among chronic hepatitis B patients receiving entecavir."