{"id":510,"date":"2026-03-02T22:37:02","date_gmt":"2026-03-02T13:37:02","guid":{"rendered":"https:\/\/www.med.osaka-u.ac.jp\/pub\/gh\/?p=510"},"modified":"2026-03-02T22:37:02","modified_gmt":"2026-03-02T13:37:02","slug":"%e8%82%9d%e8%87%93%e3%81%ae%e3%81%86%e3%81%a3%e8%a1%80%e3%81%8c%e8%82%9d%e8%87%93%e7%97%85%e3%82%92%e5%bc%95%e3%81%8d%e8%b5%b7%e3%81%93%e3%81%99%e4%bb%95%e7%b5%84%e3%81%bf%e3%82%92%e8%a7%a3%e6%98%8e","status":"publish","type":"post","link":"https:\/\/www.med.osaka-u.ac.jp\/pub\/gh\/en\/2026\/03\/02\/510\/","title":{"rendered":"Elucidation of how liver congestion causes liver disease - Identification of a new therapeutic target - (Dr. Kato, Dr. Hikita) [Gastroenterology]."},"content":{"rendered":"<p>A research group led by Dr. Seiya Kato (graduate student) and Dr. Hayato Hikita (associate professor) has clarified for the first time in the world that activation of YAP and expression of CTGF in hepatic sinusoidal endothelial cells are important as a mechanism of liver congestion, which occurs after pediatric heart surgery (Fontan surgery) and leads to liver fibrosis and liver cancer development This research will be completed by February 27, 2026. This research was published in Gastroenterology on February 27, 2026.<\/p>\n<p>For more information.<a href=\"https:\/\/www.med.osaka-u.ac.jp\/pub\/gh\/en\/activities\/results\/2025year\/hikita2026-2-26\/\" style=\"color: blue; text-decoration: underline;\">Press release here<\/a>Please see from<\/p>","protected":false},"excerpt":{"rendered":"<p>\u52a0\u85e4\u8056\u4e5f\u5148\u751f\uff08\u5927\u5b66\u9662\u751f\uff09\u3001\u758b\u7530\u96bc\u4eba\u5148\u751f\uff08\u51c6\u6559\u6388\uff09\u3089\u306e\u7814\u7a76\u30b0\u30eb\u30fc\u30d7\u304c\u3001\u5c0f\u5150\u5fc3\u81d3\u624b\u8853(\u30d5\u30a9\u30f3\u30bf\u30f3\u624b\u8853)\u5f8c\u306a\u3069\u306b\u8d77\u3053 [&hellip;]<\/p>\n","protected":false},"author":1,"featured_media":0,"comment_status":"closed","ping_status":"closed","sticky":false,"template":"","format":"standard","meta":{"footnotes":""},"categories":[3],"tags":[],"post_folder":[],"class_list":["post-510","post","type-post","status-publish","format-standard","hentry","category-pressrelease"],"_links":{"self":[{"href":"https:\/\/www.med.osaka-u.ac.jp\/pub\/gh\/en\/wp-json\/wp\/v2\/posts\/510","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/www.med.osaka-u.ac.jp\/pub\/gh\/en\/wp-json\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/www.med.osaka-u.ac.jp\/pub\/gh\/en\/wp-json\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/www.med.osaka-u.ac.jp\/pub\/gh\/en\/wp-json\/wp\/v2\/users\/1"}],"replies":[{"embeddable":true,"href":"https:\/\/www.med.osaka-u.ac.jp\/pub\/gh\/en\/wp-json\/wp\/v2\/comments?post=510"}],"version-history":[{"count":5,"href":"https:\/\/www.med.osaka-u.ac.jp\/pub\/gh\/en\/wp-json\/wp\/v2\/posts\/510\/revisions"}],"predecessor-version":[{"id":515,"href":"https:\/\/www.med.osaka-u.ac.jp\/pub\/gh\/en\/wp-json\/wp\/v2\/posts\/510\/revisions\/515"}],"wp:attachment":[{"href":"https:\/\/www.med.osaka-u.ac.jp\/pub\/gh\/en\/wp-json\/wp\/v2\/media?parent=510"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/www.med.osaka-u.ac.jp\/pub\/gh\/en\/wp-json\/wp\/v2\/categories?post=510"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/www.med.osaka-u.ac.jp\/pub\/gh\/en\/wp-json\/wp\/v2\/tags?post=510"},{"taxonomy":"post_folder","embeddable":true,"href":"https:\/\/www.med.osaka-u.ac.jp\/pub\/gh\/en\/wp-json\/wp\/v2\/post_folder?post=510"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}