{"id":977,"date":"2017-02-27T14:34:36","date_gmt":"2017-02-27T05:34:36","guid":{"rendered":"https:\/\/www.med.osaka-u.ac.jp\/pub\/mds\/?page_id=977"},"modified":"2025-12-11T12:38:45","modified_gmt":"2025-12-11T03:38:45","slug":"news","status":"publish","type":"page","link":"https:\/\/www.med.osaka-u.ac.jp\/pub\/mds\/en\/news","title":{"rendered":"NEWS"},"content":{"rendered":"<ul class=\"index_news_manual index_uline\">\n<p><!-------------------\nNEWS\u306e\u7de8\u96c6\u3059\u308b\u90e8\u5206\u306f\u3053\u3053\u304b\u3089------------------------><\/p>\n<li class=\"bana_02 sm_bana_01\">Targeting fibroblast activation protein in solid tumors via CAR-mRNA delivery promotes durable regression in solid tumor models (Scientific Reports, 2025)<\/li>\n<li class=\"bana_02 sm_bana_01\">Deficiencies in methionine, tryptophan, and niacin remodels intestinal transcriptome and gut microbiota in mice (Scientific Reports, 2025)<\/li>\n<li class=\"bana_02 sm_bana_01\">N6-methyladenosine modification and significance in pancreatic cance (Cancer Med, 2025)<\/li>\n<li class=\"bana_02 sm_bana_01\">Antisense oligonucleotide targeting nicotinamide N-methyltransferase (Mol. Ther. Nuc. Acid., 2025)<\/li>\n<li class=\"bana_02 sm_bana_01\">In vivo engineered CAR-T cell therapy: lessons built from COVID-19 mRNA vaccines (Int J Mol Sci, 2025)<\/li>\n<li class=\"bana_02 sm_bana_01\">Recent exploration of cancer biomarkers hidden within urine or blood exosomes that provide fundamental information for future cancer diagnostics (Diagnostics, 2025)<\/li>\n<li class=\"bana_02 sm_bana_01\">Non-invasive detection of tumors by volatile organic compounds in urine (Biomedicines, 2025)<\/li>\n<li class=\"bana_02 sm_bana_01\">Non-coding RNA modifications of gastrointestinal cancer (Cancer Sci, 2024)<\/li>\n<li class=\"bana_02 sm_bana_01\">A novel target of chimeric antigen receptor T-cell therapy in solid tumor (Cancer Sci, 2024)<\/li>\n<li class=\"bana_02 sm_bana_01\">Dr Hara&#8217;s paper (IBD bacterial flora) was highlighted in a cancer journal (Cancer Sci, 2024)<\/li>\n<li class=\"bana_02 sm_bana_01\">Tissue-resident memory T cells in gastrointestinal cancers: prognostic significance and therapeutic implications (Biomedicines, 2024)<\/li>\n<li class=\"bana_02 sm_bana_01\">RN7SL1 may be translated under oncogenic conditions (PNAS, 2024)<\/li>\n<li class=\"bana_02 sm_bana_01\">High N6-methyladenosine-activated TCEAL8 mRNA is a novel pancreatic cancer marker (Cancer Sci, 2024)<\/li>\n<li class=\"bana_02 sm_bana_01\">Fat and proteolysis due to methionine, tryptophan, and niacin deficiency leads to alterations in gut microbiota and immune modulation in inflammatory bowel disease (Cancer Sci, 2024)<\/li>\n<li class=\"bana_02 sm_bana_01\">The significance of signal recognition particle 9: implications for pancreatic cancer prognosis and functionality (Int J Oncol, 2024)<\/li>\n<li class=\"bana_02 sm_bana_01\">RNA methylation in inflammatory bowel disease (Cancer Sci, 2023)<\/li>\n<li class=\"bana_02 sm_bana_01\">The link of mRNA and rRNA transcription as a novel therapeutic target for cancer (Biomedicines, 2023)<\/li>\n<li class=\"bana_02 sm_bana_01\">Revealing neuropilin expression patterns in pancreatic cancer: from single-cell to therapeutic opportunities (Oncology Letters, 2023)\n<\/li>\n<li class=\"bana_02 sm_bana_01\">Systematic analysis and characterization of long non-coding RNA genes in inflammatory bowel disease (Briefing Function Genomic, 2023)<\/li>\n<li class=\"bana_02 sm_bana_01\">Drug discovery and development of miRNA-based nucleotide drugs for gastrointestinal cancer (Biomedicines, 2023)<\/li>\n<li class=\"bana_02 sm_bana_01\">Multifaced roles of desmoplastic reaction and fibrosis in pancreatic cancer progression (Cancer Science, 2023)<\/li>\n<li class=\"bana_02 sm_bana_01\">T2DB: a web database for long non-coding RNA genes in type II diabetes (Noncoding RNA, 2023)<\/li>\n<li class=\"bana_02 sm_bana_01\">The role of RNA methylation in the regulation of pancreatic cancer stem cells (Oncology Letters, 2023)<\/li>\n<li class=\"bana_02 sm_bana_01\">Cancer-specific tissue-resident memory T-cells in colorectal cancer (Br. J. Cancer, 2023)<\/li>\n<li class=\"bana_02 sm_bana_01\">m6 RNA methylation: An emerging common target in the immune response to cancer and severe acute respiratory syndrome-coronavirus-2 infection (Exp Med, 2022)<\/li>\n<li class=\"bana_02 sm_bana_01\">Emerging roles of long noncoding and circular RNAs in pancreatic ductal adenocarcinoma (Front Physiol, 2022)<\/li>\n<li class=\"bana_02 sm_bana_01\">Pancreatic cancer research beyond DNA mutations (Biomolecules, 2022)<\/li>\n<li class=\"bana_02 sm_bana_01\">Targeting the regulation of aberrant protein production pathway in gastrointestinal cancer treatment (Front Oncol, 2022)<\/li>\n<li class=\"bana_02 sm_bana_01\">Circulating cancer-associated extracellular vesicles as detection and recurrence biomarkers for pancreatic cancer (Cancer Science, 2022)<\/li>\n<li class=\"bana_02 sm_bana_01\">RNA Modification in Inflammatory Bowel Diseases (Biomedicines, 2022)<\/li>\n<li class=\"bana_02 sm_bana_01\">N6-methyladenosine methylation-regulated PLK1 cell cycle as a potential target of pancreatic adenocarcinoma (Scientific Reports, 2022)<\/li>\n<li class=\"bana_02 sm_bana_01\">Establishment of a reference single-cell RNA sequencing dataset for human pancreatic adenocarcinoma (iScience, 2022)<\/li>\n<li class=\"bana_02 sm_bana_01\">EpisomiR, a new family of miRNAs, and its possible roles in human diseases (Biomedicines, 2022)<\/li>\n<li class=\"bana_02 sm_bana_01\">Direct observation of DNA alterations induced by DNA disruptor (Scientific Reports, 2022)<\/li>\n<li class=\"bana_02 sm_bana_01\">Detection techniques for epitranscriptomic marks (Am J Physiol, 2022, in press)<\/li>\n<li class=\"bana_02 sm_bana_01\">Nematode applied technology for human tumor microenvironment research and development (Current Issues in Molecular Biology, 2022, in press)<\/li>\n<li class=\"bana_02 sm_bana_01\">Cancer metabolism challenges genomic instability and clonal evolution as therapeutic targets (Cancer Science, 2022)<\/li>\n<li class=\"bana_02 sm_bana_01\">Clinicopathological significance of MYL9 expression in pancreatic ductal adenocarcinoma  (Cancer Rep., 2021)<\/li>\n<li class=\"bana_02 sm_bana_01\">Methylosystem for Cancer Sieging Strategy (Cancers 2021)<\/li>\n<li class=\"bana_02 sm_bana_01\">Single-Molecule RNA Sequencing for Simultaneous Detection of m6A and 5mC (Scientific Reports, 2021)<\/li>\n<li class=\"bana_02 sm_bana_01\">Computational healthcare, present and future perspectives (Experimental and Therapeutic Medicine, 2021, in press)<\/li>\n<li class=\"bana_02 sm_bana_01\">Scent test using Caenorhabditis elegans to screen for early-stage pancreatic cancer (Oncotarget, 2021, in press)<\/li>\n<li class=\"bana_02 sm_bana_01\">Epithelial cell transformation and senescence as indicators of genome aging: current advances and unanswered questions (Int. J. Mol. Sci., 2021, in press)<\/li>\n<li class=\"bana_02 sm_bana_01\">Impact of one-carbon metabolism-driving epitranscriptome as a therapeutic target for gastrointestinal cancer (Int. J. Mol. Sci., 2021, in press)<\/li>\n<li class=\"bana_02 sm_bana_01\">Reproducibility of CRISPR-Cas9 Methods for generation of conditional mouse alleles (Genome Biology, correspondence, 2021, in press)<\/li>\n<li class=\"bana_02 sm_bana_01\">Ribonucleotide base enzymes and diseases (Elsevier book, 2021, in press)<br \/>\nA practical textbook for industry-academia collaboration will be published in English by Elsevier. As a result of our research, Dr. Konno et al. updated about ribonucleotide biochemistry.<\/li>\n<li class=\"bana_02 sm_bana_01\">The issues in epitranscriptomics and diseases were published in a Springer Book, 2021 (Editors, Drs. Stefan Jurga and Jan Barciszewski).<\/li>\n<li class=\"bana_02 sm_bana_01\">Collaborative research with Osaka International Cancer Institute and Kyushu University was accepted in Regenerative Therapy, 2021.<\/li>\n<li class=\"bana_02 sm_bana_01\">Graduate Student Dr. Yanagisawa&#8217;s paper was accepted in Biology, 2020.<\/li>\n<li class=\"bana_02 sm_bana_01\">Graduate Student Dr. Takeda&#8217;s paper was accepted in Cells, 2020.<\/li>\n<li class=\"bana_02 sm_bana_01\">A result of collaborative research for biodiagnosis was published in Book Chapter through industry-academia collaboration.<\/li>\n<li class=\"bana_02 sm_bana_01\">Associate Professor Masamitsu Konno&#8217;s paper was accepted for diagnosis with model organisms.<\/li>\n<li class=\"bana_02 sm_bana_01\">A result of collaborative research was accepted in Nat. Commun., 2020.<\/li>\n<li class=\"bana_02 sm_bana_01\">Graduate Student Dr. Yanagisawa&#8217;s paper was accepted in Int. J. Mol. Sci., 2020.<\/li>\n<li class=\"bana_02 sm_bana_01\">Assistant Professor Ayumu Asai&#8217;s paper was accepted in Int. J. Mol. Sci., 2020.<\/li>\n<li class=\"bana_02 sm_bana_01\">Assistant Professor Ayumu Asai&#8217;s paper was accepted in Oncotarget, 2020.<\/li>\n<li class=\"bana_02 sm_bana_01\">Assistant Professor Ayumu Asai&#8217;s paper was accepted in Cancer Letters (impact factor = 6.508), 2019 as an international collabolation research.<\/li>\n<li class=\"bana_02 sm_bana_01\">Graduate Student Dr. Tsunekuni&#8217;s paper was accepted in Scientific Reports, 2019.<\/li>\n<li class=\"bana_02 sm_bana_01\">Associate Professor Masamitsu Konno&#8217;s paper was accepted in Nature Communications, 2019.<\/li>\n<li class=\"bana_02 sm_bana_01\">International collaborative research was accepted in Genome Biology, 2019.<\/li>\n<li class=\"bana_02 sm_bana_01\">Assistant Professor Jun Koseki&#8217;s review was accepted in International cancer specialty books.<\/li>\n<li class=\"bana_02 sm_bana_01\">Graduate Student Dr. Ueda&#8217;s paper was accepted in Oncotarget, 2019.<\/li>\n<li class=\"bana_02 sm_bana_01\">Graduate Student Dr. Matsushita&#8217;s paper was accepted in ChemMedChem, 2019.<\/li>\n<li class=\"bana_02 sm_bana_01\">Associate Professor Masamitsu Konno&#8217;s Editorial on RNA modification in cancer was published in Cancer Science.<\/li>\n<li class=\"bana_02 sm_bana_01\">Collaborative research with Professor Taniguchi of the institue of scientific and<br \/> industrial research was accepted in Scientific Reports, 2019.<br \/>\nIn addition, the research results (Direct observation of anti-cancer drug<br \/> by Single molecule sequencer for the first time in the world) were press released.<br \/>\n<a href=\"http:\/\/resou.osaka-u.ac.jp\/ja\/research\/2019\/20190307_1\">http:\/\/resou.osaka-u.ac.jp\/ja\/research\/2019\/20190307_1<\/a><br \/>\n<a href=\"https:\/\/www.sanken.osaka-u.ac.jp\/toppage\/hot_topics\/topics_20190307\/\">https:\/\/www.sanken.osaka-u.ac.jp\/toppage\/hot_topics\/topics_20190307\/<\/a><br \/>\n<a href=\"https:\/\/www.jst.go.jp\/pr\/announce\/20190307\/index.html\">https:\/\/www.jst.go.jp\/pr\/announce\/20190307\/index.html<\/a><\/li>\n<li class=\"bana_02 sm_bana_01\">Graduate Student Dr. Takaoka&#8217;s paper was accepted in Cancer Science, 2019.<\/li>\n<li class=\"bana_02 sm_bana_01\">Collaborative research with Gastrointestinal Surgery in Osaka University was accepted in Cancer Research, 2019.<\/li>\n<li class=\"bana_02 sm_bana_01\">Collaborative research with Professor Gotoh of Kanazawa University was accepted in PNAS, 2019.<\/li>\n<li class=\"bana_02 sm_bana_01\">Associate Professor Masamitsu Konno&#8217;s Editorial on artificial intelligence was published in Oncotarget.<\/li>\n<li class=\"bana_02 sm_bana_01\">Dr. Asai&#8217;s paper was accepted in Heliyon, in press.<\/li>\n<li class=\"bana_02 sm_bana_01\">Graduate student Dr. Tamari&#8217;s paper (graduate; Assistant Professor of Radiotherapy Department) was accepted in Cell Death Discovery.<\/li>\n<li class=\"bana_02 sm_bana_01\">Graduate Student Dr. Toratani&#8217;s paper was accepted in Cancer Research, in press.<\/li>\n<li class=\"bana_02 sm_bana_01\">Graduate Student Dr. Toshiyama&#8217;s paper was accepted in Oncogene, in press.<\/li>\n<li class=\"bana_02 sm_bana_01\">Associate Professor Masamitsu Konno&#8217;s paper was accepted in Scientific Reports, in press.<\/li>\n<li class=\"bana_02 sm_bana_01\">Assistant Professor Jun Koseki&#8217;s paper was accepted in Scientific Reports, in press.<\/li>\n<li class=\"bana_02 sm_bana_01\">Graduate Student Dr. Toshiyama&#8217;s paper was accepted in Oncology Letters, in press.<\/li>\n<li class=\"bana_02 sm_bana_01\">Graduate Student Dr. Ohhashi&#8217;s paper was accepted in Oncology Reports, in press.<\/li>\n<li class=\"bana_02 sm_bana_01\">Graduate Student Dr. Nishizawa&#8217;s paper was accepted in Oncotarget, in press.<\/li>\n<li class=\"bana_02 sm_bana_01\">Graduate Student Dr. Nishizawa&#8217;s paper was accepted in Int J Oncol, in press.<\/li>\n<li class=\"bana_02 sm_bana_01\">Graduate Student Dr. Taketoh&#8217;s paper was accepted in Int J Oncol, in press.<\/li>\n<li class=\"bana_02 sm_bana_01\">Associate Professor Konno, the Best Award Winner:  the Best Poster Award at the Platform of Advanced Animal Model Support Grant-in-Aid for Scientific Research on the Innovative Areas was given to him.<\/li>\n<li class=\"bana_02 sm_bana_01\">Graduate Student Dr. Tsunekuni&#8217;s paper was accepted in Oncotarget, 2017.<\/li>\n<li class=\"bana_02 sm_bana_01\">Graduate Dr. Asukai&#8217;s paper was accepted in Annal. Surg. Oncol., 2017.<\/li>\n<li class=\"bana_02 sm_bana_01\">Graduate Student M.D. Baek&#8217;s paper was accepted in Oncol. Rep., 2016.<\/li>\n<li class=\"bana_02 sm_bana_01\">Graduate Dr. Miyo&#8217;s paper was accepted in Sci. Rep., 2016.<\/li>\n<li class=\"bana_02 sm_bana_01\">Assistant Professor Masamitsu Konno&#8217;s paper was accepted in Int. J. Oncology, 2017.<\/li>\n<li class=\"bana_02 sm_bana_01\">Graduate Student M.D. Hugh Colvine&#8217;s paper was accepted in Sci. Rep., 2016.<\/li>\n<li class=\"bana_02 sm_bana_01\">Assistant Professor Koich Kawamoto&#8217;s paper was accepted in Oncology Reports, 2016.<\/li>\n<li class=\"bana_02 sm_bana_01\">Graduate Dr. Miyo&#8217;s paper was accepted in Oncol. Rep., 2016.<\/li>\n<li class=\"bana_02 sm_bana_01\">Graduate Student M.D. Nishizawa&#8217;s paper was accepted in Annal. Surg. Oncology, 2016.<\/li>\n<li class=\"bana_02 sm_bana_01\">Graduate Student M.D. Noguchi&#8217;s paper was accepted in Oncol. Lett, 2016.<\/li>\n<li class=\"bana_02 sm_bana_01\">Graduates Dr. Ogawa&#8217;s paper was accepted in Biomedical Rep., 2016.<\/li>\n<li class=\"bana_02 sm_bana_01\">Assistant Professor Jun Koseki&#8217;s paper was accepted in Scientific Reports, 2016.<\/li>\n<li class=\"bana_02 sm_bana_01\">Graduate Student M.D. Sueda&#8217;s paper was accepted in Scientific Reports, 2016.<\/li>\n<li class=\"bana_02 sm_bana_01\">Graduate Dr. Hasegawa&#8217;s paper was accepted in Int. J. Oncology, 2015.<\/li>\n<li class=\"bana_02 sm_bana_01\">Assistant Professor Masamitsu Konno&#8217;s paper was accepted in PLOS ONE, 2015.<\/li>\n<li class=\"bana_02 sm_bana_01\">Graduate Student M.D. Asukai&#8217;s paper was accepted in Annal. Surg. Oncology, 2015.<\/li>\n<li class=\"bana_02 sm_bana_01\">Graduate Student M.D. Baek&#8217;s paper was accepted in Oncology Rep., 2015.<\/li>\n<li class=\"bana_02 sm_bana_01\">Graduate Student M.D. Noguchi&#8217;s paper was accepted in Cancer Sci., 2015.<\/li>\n<li class=\"bana_02 sm_bana_01\">Graduate Student M.D. Miyo&#8217;s paper was accepted in Br. J. Cancer, 2015.<\/li>\n<li class=\"bana_02 sm_bana_01\">Graduates M.D. Ogawa&#8217;s paper was accepted in PLOS ONE., 2015.<\/li>\n<li class=\"bana_02 sm_bana_01\">Graduates Dr. Nishikawa&#8217;s paper was accepted in Onlol. Rep., 2015.<\/li>\n<li class=\"bana_02 sm_bana_01\">Assistant Professor Masamitsu Konno&#8217;s paper was accepted in Regen. Therap., 2014.<\/li>\n<li class=\"bana_02 sm_bana_01\">Graduate Student M.D. Ogawa&#8217;s paper was accepted in Oncol. lett., 2014.<\/li>\n<li class=\"bana_02 sm_bana_01\">Graduate Student M.D. Hasegawa&#8217;s paper was accepted in Oncol. lett., 2014.<\/li>\n<li class=\"bana_02 sm_bana_01\">Assistant Professor Jun Koseki&#8217;s paper was accepted in Int. J. Oncol, 2014.<\/li>\n<li class=\"bana_02 sm_bana_01\">Graduate Student M.D. Hamabe&#8217;s paper was accepted in PNAS, 2014.<\/li>\n<li class=\"bana_02 sm_bana_01\">Graduate Student M.D. Colvin&#8217;s paper review was accepted in JJCO, 2014.<\/li>\n<li class=\"bana_02 sm_bana_01\">Graduate Student M.D. Hayashi&#8217;s paper was accepted in Int. J. Oncol, 2014.<\/li>\n<li class=\"bana_02 sm_bana_01\">Graduate Student M.D. Tamari&#8217;s paper was accepted in Int. J. Oncol, 2014.<\/li>\n<li class=\"bana_02 sm_bana_01\">Assistant Professor Koichi Kawamoto&#8217;s paper was accepted in J Stem Cell Res Ther, 2014.<\/li>\n<li class=\"bana_02 sm_bana_01\">Graduate Student M.D. Hasegawa&#8217;s paper was accepted in Br. J. Cancer, 2014.<\/li>\n<li class=\"bana_02 sm_bana_01\">Graduate Student M.D. Hamabe&#8217;s paper was accepted in Cancer Sci., 2014.<\/li>\n<li>Graduate Student M.D. Fukusumi&#8217;s paper was accepted in Br. J. Cancer, 2014.<\/li>\n<p><!-------------------\nNEWS\u306e\u7de8\u96c6\u3059\u308b\u90e8\u5206\u306f\u3053\u3053\u307e\u3067------------------------><\/p>\n<\/ul>\n","protected":false},"excerpt":{"rendered":"<p>Targeting fibroblast activation protein in solid tumors via CAR-mRNA delivery promotes durable regression in s &hellip; <a href=\"https:\/\/www.med.osaka-u.ac.jp\/pub\/mds\/en\/news\" class=\"more-link\"><span class=\"screen-reader-text\">&#8220;NEWS&#8221; \u306e<\/span>\u7d9a\u304d\u3092\u8aad\u3080<\/a><\/p>\n","protected":false},"author":1,"featured_media":0,"parent":0,"menu_order":0,"comment_status":"closed","ping_status":"closed","template":"","meta":{"footnotes":""},"class_list":["post-977","page","type-page","status-publish","hentry"],"aioseo_notices":[],"acf":[],"_links":{"self":[{"href":"https:\/\/www.med.osaka-u.ac.jp\/pub\/mds\/en\/wp-json\/wp\/v2\/pages\/977","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/www.med.osaka-u.ac.jp\/pub\/mds\/en\/wp-json\/wp\/v2\/pages"}],"about":[{"href":"https:\/\/www.med.osaka-u.ac.jp\/pub\/mds\/en\/wp-json\/wp\/v2\/types\/page"}],"author":[{"embeddable":true,"href":"https:\/\/www.med.osaka-u.ac.jp\/pub\/mds\/en\/wp-json\/wp\/v2\/users\/1"}],"replies":[{"embeddable":true,"href":"https:\/\/www.med.osaka-u.ac.jp\/pub\/mds\/en\/wp-json\/wp\/v2\/comments?post=977"}],"version-history":[{"count":96,"href":"https:\/\/www.med.osaka-u.ac.jp\/pub\/mds\/en\/wp-json\/wp\/v2\/pages\/977\/revisions"}],"predecessor-version":[{"id":1641,"href":"https:\/\/www.med.osaka-u.ac.jp\/pub\/mds\/en\/wp-json\/wp\/v2\/pages\/977\/revisions\/1641"}],"wp:attachment":[{"href":"https:\/\/www.med.osaka-u.ac.jp\/pub\/mds\/en\/wp-json\/wp\/v2\/media?parent=977"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}