{"id":1666,"date":"2026-08-25T11:06:28","date_gmt":"2026-08-25T02:06:28","guid":{"rendered":"https:\/\/www.med.osaka-u.ac.jp\/pub\/mds\/en\/?p=1666"},"modified":"2026-09-09T18:33:18","modified_gmt":"2026-09-09T09:33:18","slug":"hedgehog-wnt-crosstalk-in-tumor-promoting-cell-competition-dev-cell-2026-2","status":"publish","type":"post","link":"https:\/\/www.med.osaka-u.ac.jp\/pub\/mds\/en\/archives\/1666","title":{"rendered":"Hedgehog-Wnt crosstalk in tumor-promoting cell competition (Dev Cell, 2026)"},"content":{"rendered":"<p><strong>Hedgehog-Wnt crosstalk in tumor-promoting cell competition\u00a0(Dev Cell, 2026)<\/strong><\/p>\n<p>&nbsp;<\/p>\n<p>The international collaboration demonstrated that intratumoral heterogeneity promotes cancer progression through interclonal communication. This study identifies a conserved Hh\u2013Wnt signaling mechanism, enhancing invasion and tumor growth. The findings reveal Hh\u2013Wnt crosstalk as a potential therapeutic vulnerability in heterogeneous cancers.<\/p>\n","protected":false},"excerpt":{"rendered":"<p>Hedgehog-Wnt crosstalk in tumor-promoting cell competition\u00a0(Dev Cell, 2026) &nbsp; The international collabora &hellip; <a href=\"https:\/\/www.med.osaka-u.ac.jp\/pub\/mds\/en\/archives\/1666\" class=\"more-link\"><span class=\"screen-reader-text\">&#8220;Hedgehog-Wnt crosstalk in tumor-promoting cell competition (Dev Cell, 2026)&#8221; \u306e<\/span>\u7d9a\u304d\u3092\u8aad\u3080<\/a><\/p>\n","protected":false},"author":1,"featured_media":0,"comment_status":"closed","ping_status":"closed","sticky":false,"template":"","format":"standard","meta":{"_acf_changed":false,"footnotes":""},"categories":[3],"tags":[],"class_list":["post-1666","post","type-post","status-publish","format-standard","hentry","category-results"],"acf":[],"aioseo_notices":[],"_links":{"self":[{"href":"https:\/\/www.med.osaka-u.ac.jp\/pub\/mds\/en\/wp-json\/wp\/v2\/posts\/1666","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/www.med.osaka-u.ac.jp\/pub\/mds\/en\/wp-json\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/www.med.osaka-u.ac.jp\/pub\/mds\/en\/wp-json\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/www.med.osaka-u.ac.jp\/pub\/mds\/en\/wp-json\/wp\/v2\/users\/1"}],"replies":[{"embeddable":true,"href":"https:\/\/www.med.osaka-u.ac.jp\/pub\/mds\/en\/wp-json\/wp\/v2\/comments?post=1666"}],"version-history":[{"count":4,"href":"https:\/\/www.med.osaka-u.ac.jp\/pub\/mds\/en\/wp-json\/wp\/v2\/posts\/1666\/revisions"}],"predecessor-version":[{"id":1689,"href":"https:\/\/www.med.osaka-u.ac.jp\/pub\/mds\/en\/wp-json\/wp\/v2\/posts\/1666\/revisions\/1689"}],"wp:attachment":[{"href":"https:\/\/www.med.osaka-u.ac.jp\/pub\/mds\/en\/wp-json\/wp\/v2\/media?parent=1666"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/www.med.osaka-u.ac.jp\/pub\/mds\/en\/wp-json\/wp\/v2\/categories?post=1666"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/www.med.osaka-u.ac.jp\/pub\/mds\/en\/wp-json\/wp\/v2\/tags?post=1666"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}