{"id":398,"date":"2017-02-14T13:55:43","date_gmt":"2017-02-14T04:55:43","guid":{"rendered":"https:\/\/www.med.osaka-u.ac.jp\/pub\/mds\/?page_id=398"},"modified":"2020-03-31T18:11:50","modified_gmt":"2020-03-31T09:11:50","slug":"projects","status":"publish","type":"page","link":"https:\/\/www.med.osaka-u.ac.jp\/pub\/mds\/projects","title":{"rendered":"\u30d7\u30ed\u30b8\u30a7\u30af\u30c8"},"content":{"rendered":"<h3 class=\"text-center h2 blue bold bana_05 sm_bana_04 other_lbl02 f7\"><span>\u3010\u76ee\u6a19\u9054\u6210\u306e\u305f\u3081\u306e Headquarters\u3011 <sub class=\"f03\">iLAB-HQ<\/sub><\/span><\/h3>\n<div class=\"bana_08 sm_bana_06\">\n<p class=\"bana_04 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fact\uff1b\u591a\u304f\u306e\u5834\u5408\u306f\u771f\u5b9f\u3067\u306a\u3044[\u304b\u3082\u3057\u308c\u306a\u3044]\uff09\u3068\u898b\u505a\u3055\u308c\u308b\u3053\u3068\u3082\u3057\u3070\u3057\u3070\u767a\u751f\u3057\u3066\u3044\u307e\u3059\u3002\u4e00\u65b9\u3001\u30b5\u30a4\u30a8\u30f3\u30b9\u306b\u304a\u3044\u3066\u306f\u3001\u3055\u307e\u3056\u307e\u306a\u89d2\u5ea6\u304b\u3089\u691c\u8a0e\u3092\u52a0\u3048\u308b\u3053\u3068\u306b\u3088\u308a\u65e2\u5b58\u306e\u67a0\u304c\u6253\u3061\u7834\u3089\u308c\u3066\u3001\u65b0\u305f\u306a\u30a4\u30ce\u30d9\u30fc\u30b7\u30e7\u30f3\u306e\u539f\u52d5\u529b\u3068\u306a\u3063\u3066\u304d\u305f\u3053\u3068\u306f\u3088\u304f\u77e5\u3089\u308c\u3066\u3044\u307e\u3059\u3002\u3053\u306e\u3088\u3046\u306b\u3001\u8907\u6570\u306efact\u306b\u63a5\u3057\u305f\u3068\u304d\u306b\u305d\u306e\u4e2d\u304b\u3089true 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Carbon\u4ee3\u8b1d\u3001\u30a8\u30d4\u30b2\u30ce\u30e0\u306e\u5275\u85ac\u3001\u514d\u75ab\u306e\u5275\u85ac\u3001\u6838\u9178\u533b\u85ac\u54c1\u306e\u958b\u767a\u3001\u6a5f\u80fd\u6027\u6838\u9178\u306e\u63a2\u6c42\u3001\u753b\u671f\u7684\u306a\u52d5\u7269\u8a66\u9a13\u306e\u958b\u767a\u3001\u3055\u3089\u306b\u306f\u30b2\u30ce\u30e0\u30c7\u30fc\u30bf\u30d9\u30fc\u30b9\u69cb\u7bc9\u3001\u30c8\u30e9\u30f3\u30b9\u30aa\u30df\u30c3\u30af\u30b9\u89e3\u6790\u3001\u753b\u671f\u7684\u306a\u30d0\u30a4\u30aa\u30de\u30fc\u30ab\u30fc\u3001\u3053\u308c\u3089\u306e\u767a\u5c55\u3068\u3057\u3066\u3001\u518d\u751f\u533b\u5b66\u3001\u30ea\u30d7\u30ed\u30b0\u30e9\u30df\u30f3\u30b0\u3001\u30ca\u30a4\u30fc\u30d6ES\u306e\u7814\u7a76\u3001\u8133\u79d1\u5b66\u3068\u884c\u52d5\u628a\u63e1\u306a\u3069\u3001\u591a\u5c90\u306e\u7bc4\u56f2\u306b\u308f\u305f\u3063\u3066\u304a\u308a\u3001\u4e0a\u8a18\u306e\u67a0\u7d44\u307f\u3092\u30d7\u30e9\u30c3\u30c8\u30d5\u30a9\u30fc\u30e0\u3068\u3057\u306a\u304c\u3089\u5404\u30e1\u30f3\u30d0\u30fc\u304c\u5927\u304d\u304f\u767a\u5c55\u3055\u305b\u3066\u3044\u307e\u3059\u3002<\/br><\/p>\n<p>\u6bce\u65e5\u3001\u30e1\u30f3\u30d0\u30fc\u304c\u697d\u3057\u3093\u3067\u524d\u9032\u3057\u3066\u3044\u308b\u3053\u3068\u3001\u3053\u306e\u3053\u3068\u306b\u5c3d\u304d\u308b\u3068\u601d\u3044\u307e\u3059\u3002\u305d\u306e\u305f\u3081\u306e\u7d44\u7e54\u3065\u304f\u308a\u304c\u91cd\u8981\u3067\u3059\u3002\u300c\u3053\u3093\u306a\u9762\u767d\u3044\u3053\u3068\u304c\u3042\u308b\u3088\u300d\u3068\u3044\u3046\u3053\u3068\u304b\u3089\u3001\u300c\u3067\u306f\u3084\u3063\u3066\u307f\u3088\u3046\u300d\u3092\u8a31\u3057\u3066\u3042\u3052\u308b\u3068\u3001\u82e5\u8005\u306e\u76ee\u304c\u751f\u304d\u751f\u304d\u3068\u3057\u3066\u304d\u307e\u3059\u3002\u840c\u82bd\u7814\u7a76\u304c\u9032\u307f\u307e\u3059\u3002\u3082\u3061\u308d\u3093\u306e\u3053\u3068\u3067\u3059\u304c\u3001\u8a08\u753b\u6027\u306f\u91cd\u8981\u3067\u3059\u3057\u3001\u81ea\u7136\u6dd8\u6c70\u3055\u308c\u307e\u3059\u3002\u30b9\u30c8\u30c3\u30d7\u3092\u304b\u3051\u308b\u306e\u3082\u91cd\u8981\u306a\u5f79\u5272\u3067\u3059\u3002 <\/br><\/p>\n<p>\u3053\u306e\u3088\u3046\u306a\u30c7\u30fc\u30bf\u30b5\u30a4\u30a8\u30f3\u30b9\u306e\u7814\u7a76\u306e\u69cb\u3048\u65b9\u306f\u300121\u4e16\u7d00\u578b\u306e\u751f\u547d\u79d1\u5b66\u7814\u7a76\u3068\u3057\u3066\u6ce8\u76ee\u3055\u308c\u3066\u3044\u307e\u3059\u3002\u5bfe\u8c61\u3092\u8907\u773c\u8996\u3057\u306a\u304c\u3089\u7d71\u5408\u3057\u3066\u91cd\u8981\u306a\u3068\u3053\u308d\u3092\u629c\u304d\u51fa\u3059\u80fd\u529b\u306f\u3001\u4eba\u9593\u306a\u3089\u3067\u306f\u306e\u80fd\u529b\u3067\u3042\u308a\u3001\u4eca\u306eAI\uff08\u4eba\u5de5\u77e5\u80fd\uff09\u3082\u307e\u3060\u9054\u6210\u3067\u304d\u307e\u305b\u3093\u3002\u3053\u308c\u306f\u8a00\u8a9e\u306e\u5b66\u7fd2\u3068\u4f3c\u305f\u3068\u3053\u308d\u304c\u3042\u308a\u3001\u82e5\u3044\u6642\u4ee3\u306b\u96c6\u4e2d\u3057\u305f\u30c8\u30ec\u30fc\u30cb\u30f3\u30b0\u3092\u7a4d\u3080\u3053\u3068\u304c\u7fd2\u5f97\u306b\u52b9\u679c\u7684\u3068\u3055\u308c\u3066\u3044\u307e\u3059\u3002<\/br><\/p>\n<p>\u5c06\u6765\u306e\u30ea\u30fc\u30c0\u3068\u306a\u308b\u81e8\u5e8a\u533b\u306b\u3082\u7814\u7a76\u8005\u306b\u3082\u3001\u305d\u306e\u3088\u3046\u306a\u77e5\u8b58\u3068\u6280\u8853\u306e\u7d20\u990a\u3092\u8eab\u306b\u3064\u3051\u3066\u9802\u304d\u3001\u4e16\u754c\u3092\u30ea\u30fc\u30c9\u3067\u304d\u308b\u9038\u6750\u306e\u80b2\u6210\u3068\u8f29\u51fa\u3057\u3066\u3044\u304f\u3053\u3068\u304c\u3001\u672c\u8b1b\u5ea7\u304c\u671b\u3080\u3068\u3053\u308d\u306e\uff11\u3064\u3067\u3082\u3042\u308a\u307e\u3059\u3002\u3053\u306e\u3088\u3046\u306a\u51fa\u53e3\u3068\u3057\u3066\u306f\u8fd1\u3044\u5c06\u6765\u306b\u9069\u78ba\u533b\u7642\uff08\u7cbe\u5bc6\u533b\u7642\uff0cPrecision Medicine\uff09\u306b\u8ca2\u732e\u3067\u304d\u308c\u3070\u3068\u8003\u3048\u3066\u3044\u307e\u3059\u3002\n<\/p>\n<p class=\"txt_icon01 bana_01 blue f2 bold\">\u7814\u7a76\u5185\u5bb9\uff1a<\/p>\n<ul class=\"cont_li_style01 bana_04 sm_bana_03\">\n<li class=\"bana_03 sm_bana_02\"><span class=\"f1 blue\">\u2460 \u753b\u671f\u7684\u306a\u65b0\u3057\u3044\u751f\u7269\u8a3a\u65ad\u30d0\u30a4\u30aa\u30de\u30fc\u30ab\u30fc<\/span><br \/>\n\u30d2\u30c8\u306e\u75c5\u614b\u306f\u591a\u65b9\u9762\u304b\u3089\u8a3a\u65ad\u3057\u3066\u3044\u304f\u3053\u3068\u304c\u91cd\u8981\u3067\u3059\u3002\u307e\u305f\u3001\u65b0\u3057\u3044\u6280\u8853\u306e\u767a\u898b\u306f\u3001\u5f93\u524d\u306e\u5ef6\u9577\u7dda\u4e0a\u306b\u306a\u3044\u65ac\u65b0\u306a\u767a\u60f3\u3068\u305d\u308c\u3092\u691c\u8a3c\u3059\u308b\u30a2\u30ab\u30c7\u30df\u30a2\u306e\u76ee\u306e\u4e21\u65b9\u304c\u5fc5\u8981\u3067\u3059\u3002\u305d\u306e\u70b9\u3067\u3001\u79c1\u305f\u3061\u306f\u7dda\u866b\u3092\u7528\u3044\u305f\u65b0\u3057\u3044\u30d0\u30a4\u30aa\u30de\u30fc\u30ab\u30fc\u8a3a\u65ad\u6cd5\u306b\u95a2\u3057\u3066\u3001\u30a2\u30ab\u30c7\u30df\u30a2\u3068\u3057\u3066\u8208\u5473\u3068\u6301\u3063\u3066\u7814\u7a76\u3092\u9032\u3081\u3066\u3044\u307e\u3059\u3002\u4ee4\u548c2\u5e744\u6708\u304b\u3089\u306fHIROTSU\u30d0\u30a4\u30aa\u30b5\u30a4\u30a8\u30f3\u30b9\u793e\u3068\u5171\u540c\u7814\u7a76\u3092\u958b\u59cb\u3057\u307e\u3057\u305f\u3002<\/li>\n<\/ul>\n<ul class=\"cont_li_style01 bana_04 sm_bana_03\">\n<li class=\"bana_03 sm_bana_02\"><span class=\"f1 blue\">\u2461 \u5148\u7aef\u8a08\u6e2c\u306b\u3088\u308b\u65b0\u3057\u3044\u30b7\u30fc\u30af\u30a8\u30f3\u30b9\u6280\u8853<\/span><br \/>\n\u73fe\u5728\u3067\u306f\u6b21\u4e16\u4ee3\u30b7\u30fc\u30af\u30a8\u30f3\u30b5\u30fc\u306e\u6280\u8853\u304c\u6c4e\u7528\u5316\u305b\u308c\u3066\u3044\u307e\u3059\u3002\u305d\u3053\u3067\u3001\u305d\u306e\u6b21\u4e16\u4ee3\u30b7\u30fc\u30af\u30a8\u30f3\u30b5\u30fc\u306e\u3055\u3089\u306b\u305d\u306e\u5148\u3092\u884c\u304f\u6280\u8853\u3068\u3057\u3066\u3001\u79c1\u305f\u3061\u306f\u8cea\u91cf\u5206\u6790\u6cd5\u3068\u91cf\u5b50\u30b7\u30fc\u30af\u30a8\u30f3\u30b5\u30fc\u306b\u3088\u308b\u89aa\u5c55\u958b\u306b\u53d6\u308a\u7d44\u3093\u3067\u3044\u307e\u3059\u3002\u524d\u8005\u306f\u3001\u3044\u3067\u3042\u682a\u5f0f\u4f1a\u793e\u3068\u5171\u540c\u7814\u7a76\u3067\u3001\u307e\u305f\u5f8c\u8005\u306f\u5927\u962a\u5927\u5b66\u7523\u696d\u79d1\u5b66\u7814\u7a76\u6240\u306e\u8c37\u53e3\u6b63\u8f1d\u6559\u6388\u3068\u5354\u50cd\u3057\u305f\u7814\u7a76\u3067\u63a8\u9032\u3057\u3066\u3044\u307e\u3059\u3002<\/li>\n<li class=\"bana_03 sm_bana_02\"><span class=\"f1 blue\">\u2462 \u5148\u7aef\u6280\u8853\u306e\u533b\u7642\u306e\u793e\u4f1a\u5b9f\u88c5<\/span><br \/>\n\u6d88\u5316\u5668\u5916\u79d1\u3092\u306f\u3058\u3081\u3068\u3057\u305f\u81e8\u5e8a\u8b1b\u5ea7\u3068\u5bc6\u306b\u9023\u643a\u3092\u7d44\u307f\u306a\u304c\u3089\u3001\u5148\u7aef\u79d1\u5b66\u3092\u7406\u89e3\u3057\u3001\u3053\u306e\u9032\u6b69\u306e\u65e9\u3044\u6642\u4ee3\u3067\u30ea\u30fc\u30c0\u30b7\u30c3\u30d7\u3092\u767a\u63ee\u3067\u304d\u308b\u9038\u6750\u306e\u80b2\u6210\u306b\u53d6\u308a\u7d44\u3093\u3067\u3044\u307e\u3059\u3002\u533b\u7642\u6cd5\u4eba\u9326\u79c0\u4f1a\u3001\u533b\u7642\u6cd5\u4eba\u5354\u548c\u4f1a\u3067\u793e\u4f1a\u30cb\u30fc\u30ba\u3092\u8e0f\u307e\u3048\u306a\u304c\u3089\u30a2\u30ab\u30c7\u30df\u30a2\u3068\u3057\u3066\u5c55\u958b\u3057\u3066\u3044\u307e\u3059\u3002<\/li>\n<li class=\"bana_03 sm_bana_02\"><span class=\"f1 blue\">\u2463 \u5148\u7aef\u30e2\u30c7\u30eb\u52d5\u7269<\/span><br \/>\n\u30d2\u30c8\u306b\u5bfe\u3059\u308b\u524d\u81e8\u5e8a\u8a66\u9a13\u3068\u3057\u3066\u3001\u30e2\u30c7\u30eb\u52d5\u7269\u3092\u7528\u3044\u305f\u52d5\u7269\u5b9f\u9a13\u3092\u9032\u3081\u3066\u3044\u307e\u3059\u3002\u5e0c\u5c11\u75be\u60a3\u3001\u96e3\u75c5\u3001\u7279\u306b\u907a\u4f1d\u6027\u75be\u60a3\u3067\u306fiPS\u6280\u8853\u306b\u3088\u308b\u75be\u60a3\u7814\u7a76\u3068\u3068\u3082\u306b\u3001\u5148\u7aef\u52d5\u7269\u30e2\u30c7\u30eb\u3067\u306e\u7814\u7a76\u304c\u91cd\u8981\u3067\u3059\u3002\u30e6\u30cb\u30fc\u30c6\u30c3\u30af\u682a\u5f0f\u4f1a\u793e\u3068\u5171\u540c\u7814\u7a76\u3092\u5b9f\u65bd\u3057\u3066\u8fc5\u901f\u304b\u3064\u7684\u78ba\u306a\u3053\u306e\u8ab2\u984c\u306e\u89e3\u6c7a\u306b\u53d6\u308a\u7d44\u3093\u3067\u3044\u307e\u3059\u3002<\/li>\n<li class=\"bana_03 sm_bana_02\"><span class=\"f1 blue\">\u2464 \u81b5\u304c\u3093\u306e\u8d85\u65e9\u671f\u8a3a\u65ad\u3092\u53ef\u80fd\u306b\u3059\u308b\u30d0\u30a4\u30aa\u30de\u30fc\u30ab\u30fc\u306e\u958b\u767a<\/span><br \/>\n\u6d88\u5316\u5668\u5916\u79d1\u3068\u306e\u5354\u50cd\u3057\u305f\u7814\u7a76\u3067\u9032\u3081\u3066\u3044\u307e\u3059\u3002\u81e8\u5e8a\u7684\u306b\u306f\u3001\u81b5\u304c\u3093\u3067\u306f\u3001\u30b8\u30a7\u30e0\u30b6\u30fc\u30eb\uff08\u30b2\u30e0\u30b7\u30bf\u30d3\u30f3\uff09\u3084S\uff11\u304c\u6cbb\u7642\u85ac\u3068\u3057\u3066\u7528\u3044\u3089\u308c\u3066\u3044\u307e\u3059\u3002\u81b5\u764c\u306e\u4e88\u5f8c\u306f\u5168\u304c\u3093\u306e\u4e2d\u3067\u3082\u6975\u3081\u3066\u60aa\u304f\u3001\u767a\u898b\u6642\u306b\u306f\u9032\u884c\u304c\u3093\u3067\u3042\u308b\u3053\u3068\u304c\u3057\u3070\u3057\u3070\u3042\u308a\u307e\u3059\u3002\u307e\u305f\u305d\u306e\u5f8c\u306e\u9032\u884c\u3082\u65e9\u304f\u3001\u9060\u9694\u81d3\u5668\u3078\u306e\u8ee2\u79fb\u3084\u6cbb\u7642\u5f8c\u306e\u518d\u767a\u3092\u5f15\u304d\u8d77\u3053\u3057\u307e\u3059\u3002\u5f53\u7136\u306e\u3053\u3068\u306a\u304c\u3089\u3001\u81b5\u304c\u3093\u3067\u306e\u65e9\u671f\u8a3a\u65ad\u306f\u6975\u3081\u3066\u91cd\u8981\u3067\u3042\u308b\u3068\u3055\u308c\u3001\u305d\u306e\u65e9\u671f\u8a3a\u65ad\u306e\u30d0\u30a4\u30aa\u30de\u30fc\u30ab\u30fc\u306e\u958b\u767a\u306f\u5185\u5916\u306e\u7814\u7a76\u8005\u304c\u3057\u306e\u304e\u3092\u524a\u3063\u3066\u3044\u308b\u8ab2\u984c\u3067\u3059\u3002\u79c1\u305f\u3061\u306f\u3001\u6587\u90e8\u79d1\u5b66\u7701\u57fa\u76e4\u7814\u7a76S\u3067\u3001\u65e9\u671f\u81b5\u304c\u3093\u306e\u30d0\u30a4\u30aa\u30de\u30fc\u30ab\u30fc\u306e\u958b\u767a\u7814\u7a76\u3092\u5206\u62c5\u3055\u305b\u3066\u3044\u305f\u3060\u3044\u3066\u3044\u307e\u3059\u3002<\/li>\n<li class=\"bana_03 sm_bana_02\"><span class=\"f1 blue\">\u2465 \u30ef\u30f3\u30ab\u30fc\u30dc\u30f3\u4ee3\u8b1d<\/span><br \/>\n\u304c\u3093\u7d30\u80de\u306b\u306f\u8907\u6570\u306e\u7570\u5e38\u304c\u767a\u751f\u3057\u3066\u3044\u308b\u304c\u3001\u79c1\u9054\u3092\u542b\u3080\u5185\u5916\u306e\u7814\u7a76\u306e\u6210\u679c\u306b\u3088\u308a\u3001 \u30ef\u30f3\u30ab\u30fc\u30dc\u30f3\uff08one carbon\uff09\u4ee3\u8b1d\u306e\u91cd\u8981\u6027\u306f1940\u5e74\u4ee3\u304b\u3089\u6307\u6458\u3055\u308c\u3066\u304d\u307e\u3057\u305f\u3002\u304c\u3093\u5275\u85ac\u3068\u3057\u3066\u3001\u8449\u9178\u62ee\u6297\uff081949\u5e74\uff09\u30015FU\uff081957\u5e74\uff09\u3001Gemcitabine\uff081984\u5e74\uff09\u3001Ap3A\u52a0\u6c34\u9175\u7d20\uff081994\u5e74\uff09\u304c\u6b74\u53f2\u7684\u306b\u8a66\u307f\u3089\u308c\u3001\u6700\u8fd1\u3067\u306fTAS-102\uff082014\u5e74\uff09\u304c\u5b9f\u7528\u5316\u3055\u308c\u3066\u3044\u307e\u3059\u304c\u3001\u3053\u308c\u3089\u306f\u3044\u305a\u308c\u3082Tetrahydrofolate(THF)\u3068S-Adenosyl Methionine(SAM)\u304c\u5a92\u4ecb\u3059\u308b\u30e1\u30c1\u30eb\u57fa\u306e\u8131\u7740\u53cd\u5fdc\u3092\u57fa\u8ef8\u3068\u3057\u305f\u30ef\u30f3\u30ab\u30fc\u30dc\u30f3\u4ee3\u8b1d\u3068\u79f0\u3055\u308c\u308b\u30cd\u30c3\u30c8\u30ef\u30fc\u30af\u3068\u3057\u3066\u628a\u63e1\u3055\u308c\u3066\u3044\u308b\u3082\u306e\u3068\u3057\u3066\u3001\u8a3a\u65ad\u6cbb\u7642\u5b66\u3068\u3057\u3066\u5927\u304d\u304f\u306fGlycine\u3068Serine\u4ee3\u8b1d\u306e\u4e00\u90e8\u306b\u4f4d\u7f6e\u3059\u308b\u53cd\u5fdc\u751f\u6210\u7269\u3092\u6a19\u7684\u3068\u3057\u3066\u3044\u307e\u3059\u3002\u3053\u306e\u30ef\u30f3\u30ab\u30fc\u30dc\u30f3\u4ee3\u8b1d\u3067\u3001\u6b74\u53f2\u7684\u306b\u91cd\u8981\u306a\u5206\u5b50\u306e\uff11\u3064Ap3A\u52a0\u6c34\u9175\u7d20\u306f\u3001\u7c73\u56fd\u3067\u68ee\u6b63\u6a39\uff08\u73fe\u4e5d\u5dde\u5927\u5b66\u6559\u6388\uff09\u30fb\u77f3\u4e95\u3089\u304c\u30af\u30ed\u30fc\u30cb\u30f3\u30b0\u3068\u89e3\u6790\u3092\u3057\u3066\u304d\u307e\u3057\u305f\u3002\u305d\u306e\u5f8c\u3053\u306e\u7814\u7a76\u304b\u3089\u3001\u5f53\u6642\u30dd\u30b9\u30c9\u30af\u3067\u3042\u3063\u305fGeorge A Calin\u535a\u58eb\uff08\u73feMD Anderson Cancer Center\u6559\u6388\uff09\u306b\u3088\u308b\u4e16\u754c\u3067\u521d\u3081\u3066\u304c\u3093\u3067\u30de\u30a4\u30af\u30edRNA\u306e\u767a\u898b\u306b\u7e4b\u304c\u308a\u307e\u3057\u305f\u3002Calin\u535a\u58eb\u306e\u3082\u3068\u306b\u306f\u962a\u5927\u304b\u3089\u8907\u6570\u540d\u306e\u6d88\u5316\u5668\u5916\u79d1\u533b\u304c\u7559\u5b66\u3057\u3001\u3055\u3089\u306b\u975e\u30b3\u30fc\u30c9RNA\u306e\u7814\u7a76\u306b\u8ca2\u732e\u3057\u307e\u3057\u305f\u3002\u3053\u306e\u3088\u3046\u306a\u304c\u3093\u306b\u65bc\u3051\u308bC1\u4ee3\u8b1d\u304c\u95a2\u308f\u308b\u30e1\u30ab\u30cb\u30ba\u30e0\u306f\u3001\u8449\u9178\u4ee3\u8b1d\u3001\u30e1\u30c1\u30aa\u30cb\u30f3\u4ee3\u8b1d\u3001\u786b\u9178\u57fa\u8ee2\u79fb\u53cd\u5fdc\u306e\uff13\u8005\u306e\u4ea4\u5dee\u70b9\u3068\u3057\u3066\u3001\u8449\u9178\u306f\u6838\u9178\u5408\u6210\u3001\u786b\u5316\u306f\u6d3b\u6027\u9178\u7d20\u5236\u5fa1\u3001\u30e1\u30c1\u30aa\u30cb\u30f3\u306f\u30dd\u30ea\u30a2\u30df\u30f3\uff08\u30aa\u30eb\u30cb\u30c1\u30f3\u8131\u70ad\u9178\u9175\u7d20[ODC]\uff09\u304b\u3089\u30ea\u30b8\u30f3\u8131\u30e1\u30c1\u30eb\u5316\u9175\u7d20[KDM]\u306e\u30e1\u30c1\u30eb\u5316\u53cd\u5fdc\u3067\u305d\u308c\u305e\u308c\u91cd\u8981\u306a\u5f79\u5272\u3092\u62c5\u3044\u307e\u3059\u3002\u6b8b\u5b58\u304c\u3093\u3067\u306fODC\u4e0b\u6d41\u306eSAM\u304c\u5897\u52a0\u3057\u3001KDM\u306e\u91cf\u3068\u6d3b\u6027\u304c\u5897\u52a0\u3057\u3066\u3044\u307e\u3059\u3002\u6d88\u5316\u5668\u6b8b\u5b58\u304c\u3093\u306e\u4e88\u5f8c\u89e3\u6790\u304b\u3089\u3001\u30ef\u30f3\u30ab\u30fc\u30dc\u30f3\uff08Serine\uff09\u4ee3\u8b1d\u306e\u30df\u30c8\u30b3\u30f3\u30c9\u30ea\u30a2\u9175\u7d20\u304c\u60a3\u8005\u4e88\u5f8c\u3068\u6709\u610f\u306b\u76f8\u95a2\u3057\u3066\u3044\u308b\u3053\u3068\u304b\u3089\u3001\u5c06\u6765\u7684\u306a\u6a19\u7684\u3068\u3057\u3066\u91cd\u8981\u6027\u304c\u793a\u5506\u3055\u308c\u307e\u3059\u3002\u304c\u3093\u7d30\u80de\u3067\u7279\u7570\u7684\u306b\u30ef\u30f3\u30ab\u30fc\u30dc\u30f3\u4ee3\u8b1d\u3092\u963b\u5bb3\u3059\u308b\u963b\u5bb3\u5264\u306f\u3001\u6b63\u5e38\u7d30\u80de\u306e\u7d30\u80de\u8cea\u9175\u7d20\u306b\u306f\u5f71\u97ff\u3092\u4e0e\u3048\u306a\u3044\u306e\u3067\u3001\u5275\u85ac\u306e\u6a19\u7684\u3068\u3057\u3066\u671f\u5f85\u3055\u308c\u3066\u3044\u307e\u3059\u3002<\/li>\n<li class=\"bana_03 sm_bana_02\"><span class=\"f1 blue\">\u2466 \u304c\u3093\u5e79\u7d30\u80de\u306e\u4ee3\u8b1d<\/span><br \/>\n\u8fd1\u672a\u6765\u306e\u533b\u7642\u3092\u76ee\u6307\u3057\u305f\u75c5\u614b\u306e\u89e3\u6790\u3084\u753b\u671f\u7684\u306a\u8a3a\u65ad\u30fb\u6cbb\u7642\u306e\u5275\u51fa\u306e\u305f\u3081\u306b\u3001\u304c\u3093\u5e79\u7d30\u80de\u3092\u6a19\u7684\u3068\u3057\u305f\u958b\u767a\u7814\u7a76\u306b\u5927\u304d\u306a\u671f\u5f85\u304c\u304b\u3051\u3089\u308c\u3066\u3044\u307e\u3059\u3002\u304c\u3093\u5e79\u7d30\u80de\u3067\u306f\u3001\u6b63\u5e38\u306e\u4f53\u6027\u5e79\u7d30\u80de\u3068\u306f\u7570\u306a\u3063\u305f\u751f\u7269\u5b66\u7684\u306a\u7279\u5fb4\u3092\u6709\u3059\u308b\u3053\u3068\u304c\u660e\u3089\u304b\u306b\u3055\u308c\u3064\u3064\u3042\u308a\u3001\u305d\u306e\u91cd\u8981\u306a\u7279\u5fb4\u306e\uff11\u3064\u304c\u304c\u3093\u5e79\u7d30\u80de\u306e\u4ee3\u8b1d\u7279\u6027\u3067\u3059\u3002\u4e0a\u8ff0\u306e\u30ef\u30f3\u30ab\u30fc\u30dc\u30f3\u4ee3\u8b1d\u306f\u3001\u305d\u306e\u8981\u3068\u3057\u3066\u306e\u9375\u3092\u63e1\u308b\u3082\u306e\u3067\u3059\u3002\u79c1\u9054\u306f\u3001\u6700\u65b0\u306e\u6280\u8853\u3092\u6d3b\u7528\u3057\u3066\u3001\u304c\u3093\u5e79\u7d30\u80de\u306e\u89e3\u660e\u3092\u9032\u3081\u3066\u3044\u307e\u3059\u3002\u3053\u308c\u307e\u3067\u306b\u69d8\u3005\u306a\u6297\u304c\u3093\u5264\u7b49\u304c\u304c\u3093\u5e79\u7d30\u80de\u306b\u53ca\u307c\u3059\u5f71\u97ff\u3092\u7814\u7a76\u3057\u3066\u660e\u3089\u304b\u306b\u3057\u3066\u304d\u307e\u3057\u305f\u3002<\/li>\n<li class=\"bana_03 sm_bana_02\"><span class=\"f1 blue\">\u2467 \u6838\u9178\u8a3a\u65ad\u6280\u8853\u3068\u533b\u85ac\u54c1\u306e\u793e\u4f1a\u5b9f\u88c5<\/span><br \/>\n\u6838\u9178\u3092\u5fdc\u7528\u3057\u305f\u8a3a\u65ad\u3068\u6cbb\u7642\u306b\u5927\u304d\u306a\u671f\u5f85\u304c\u639b\u304b\u3063\u3066\u3044\u307e\u3059\u3002\u6838\u9178\u306e\u4ee3\u8b1d\u3068\u4fee\u98fe\u306b\u304a\u3044\u3066\u3082\u3001\u30ef\u30f3\u30ab\u30fc\u30dc\u30f3\u4ee3\u8b1d\u306f\u91cd\u8981\u306a\u5f79\u5272\u3092\u62c5\u3063\u3066\u3044\u307e\u3059\u3002\u4f8b\u3048\u3070\u3001\u30e1\u30c1\u30eb\u5316\u306f\u30ef\u30f3\u30ab\u30fc\u30dc\u30f3\u4ee3\u8b1d\u306eSAM\u304c\u76f4\u63a5\u95a2\u308f\u3063\u3066\u3044\u307e\u3059\u3002\u79c1\u9054\u306f\u3001\u30df\u30c8\u30b3\u30f3\u30c9\u30ea\u30a2\u306e\u9178\u5316\u7684\u30ea\u30f3\u9178\u5316\u304cSAM\u306e\u5236\u5fa1\u3092\u901a\u3058\u3066\u3001\u304c\u3093\u7d30\u80de\u306e\u751f\u7269\u5b66\u7684\u60aa\u6027\u5ea6\u306e\u6c7a\u5b9a\u306b\u91cd\u8981\u306a\u5f79\u5272\u3092\u679c\u305f\u3057\u3066\u3044\u308b\u3053\u3068\u3092\u660e\u3089\u304b\u306b\u3057\u3066\u304d\u307e\u3057\u305f\u3002\u6838\u9178\u3092\u7528\u3044\u305f\u958b\u767a\u7814\u7a76\u306f\u3001\u6a5f\u80fd\u6027\u6838\u9178\u3092\u7528\u3044\u305f\u6cbb\u7642\u3084\u3001\u753b\u671f\u7684\u306a\u30d0\u30a4\u30aa\u30de\u30fc\u30ab\u30fc\u306b\u3088\u308b\u8a3a\u65ad\u306b\u304a\u3044\u3066\u304d\u308f\u3081\u3066\u6709\u7528\u3067\u3042\u308b\u3068\u671f\u5f85\u3055\u308c\u307e\u3059\u3002\u5927\u962a\u5927\u5b66\u672a\u6765\u533b\u7642\u30bb\u30f3\u30bf\u30fc\u3067\u652f\u63f4\u3055\u308c\u3066\u3044\u307e\u3059\u3002<\/p>\n<li>\n<li class=\"bana_03 sm_bana_02\"><span class=\"f1 blue\">\u2468 \u65b0\u3057\u3044\u6838\u9178\u4fee\u98fe\u306e\u767a\u898b<\/span><br \/>\n\u6b21\u4e16\u4ee3\u30b7\u30fc\u30af\u30a8\u30f3\u30b9\u6280\u8853\u3067\u3001DNA\u306eA,T,G,C\u914d\u5217\u306f\u9ad8\u901f\u306b\u8aad\u3081\u308b\u3088\u3046\u306b\u306a\u3063\u3066\u304d\u307e\u3057\u305f\u3002\u3053\u306e\u30b7\u30fc\u30af\u30a8\u30f3\u30b5\u30fc\u306e\u6280\u8853\u9769\u65b0\u306b\u306f\u773c\u3092\u898b\u5f35\u308b\u3082\u306e\u304c\u3042\u308a\u3001\u3053\u3053\u304b\u3089\u5f97\u3089\u308c\u3066\u304f\u308b\u5927\u5bb9\u91cf\u306e\u30b2\u30ce\u30e0\u60c5\u5831\u306f\u75be\u60a3\u306e\u30c7\u30fc\u30bf\u30b5\u30a4\u30a8\u30f3\u30b9\u306e\u57fa\u672c\u3092\u306a\u3059\u3082\u306e\u3067\u3059\u3002\u3057\u304b\u3057\u540c\u6642\u306b\u3001\u5f93\u6765\u6cd5\u306eA,T,G,C\u914d\u5217\u306e\u6c7a\u5b9a\u304b\u3089\u306f\u89e3\u8aad\u3067\u304d\u306a\u3044\uff08\u898b\u3048\u306a\u304b\u3063\u305f\uff09\u6838\u9178\u306e\u4fee\u98fe\u304c\u3042\u308b\u3053\u3068\u304c\u77e5\u3089\u308c\u3066\u3044\u307e\u3059\u3002\u3053\u306e\u3088\u3046\u306a\u4fee\u98fe\u306b\u306f\u5927\u304d\u304f\u5206\u3051\u3066DNA\u3068RNA\u306e\u4fee\u98fe\u304c\u3042\u308a\u307e\u3059\u3002\u305d\u308c\u305e\u308c\u8a08\u6e2c\u6cd5\u304c\u3042\u308a\u307e\u3059\u304c\u3001\u3067\u304d\u308b\u3060\u3051\u7db2\u7f85\u6027\u3068\u89e3\u50cf\u5ea6\u3092\u4e21\u7acb\u3055\u305b\u305f\u304b\u305f\u3061\u3067\u30d7\u30ed\u30d5\u30a1\u30a4\u30ea\u30f3\u30b0\u3059\u308b\u3053\u3068\u3092\u9032\u3081\u3066\u3044\u307e\u3059\u3002\u6b21\u4e16\u4ee3\u30b7\u30fc\u30af\u30a8\u30f3\u30b5\u30fc\u3068\u3068\u3082\u306b\u3001\u8cea\u91cf\u5206\u6790\u6cd5\u304c\u529b\u3092\u767a\u63ee\u3057\u3066\u3044\u307e\u3059\u3002\u5f97\u3089\u308c\u305f\u30c7\u30fc\u30bf\u306f\u72ec\u81ea\u306e\u624b\u6cd5\u3067\u30c7\u30fc\u30bf\u30de\u30a4\u30cb\u30f3\u30b0\u3092\u9032\u3081\u307e\u3059\u3002\u3053\u306e\u3088\u3046\u306a\u6838\u9178\u306e\u4fee\u98fe\u306f\u3001\u764c\u306e\u65e9\u671f\u75c5\u5909\u3067\u91cd\u8981\u306a\u3082\u306e\u304c\u3042\u308a\u3001\u958b\u767a\u7814\u7a76\u3092\u9032\u3081\u3066\u3044\u307e\u3059\u3002\u4e00\u65b9\u3067\u3001\u30b2\u30ce\u30e0\u7de8\u96c6\u306f\u3001CRISPER-CAS\u306a\u3069\u306e\u767b\u5834\u3067\u3001\u6bd4\u8f03\u7684\u5bb9\u6613\u306b\u7814\u7a76\u5ba4\u30ec\u30d9\u30eb\u3067\u884c\u3048\u308b\u3088\u3046\u306b\u306a\u3063\u3066\u304d\u307e\u3057\u305f\u3002\u79c1\u305f\u3061\u3082\u65e5\u5e38\u7684\u306b\u4f7f\u7528\u3057\u3066\u3044\u307e\u3059\u3002\u307e\u305f\u958b\u767a\u4e2d\u3067\u8a73\u7d30\u306f\u8a18\u305b\u307e\u305b\u3093\u304cin vivo\u306e\u30b2\u30ce\u30e0\u7de8\u96c6\u3082\u7814\u7a76\u3092\u9032\u3081\u3066\u3044\u307e\u3059\u3002\u3053\u306e\u3088\u3046\u306a\u7814\u7a76\u306f\u3001\u7279\u306b\u6838\u9178\u30a2\u30ca\u30ed\u30b0\u306e\u7814\u7a76\u306b\u3082\u5927\u3044\u306b\u5f79\u7acb\u3064\u6280\u8853\u3068\u3057\u3066\u91cd\u5b9d\u3055\u308c\u3044\u307e\u3059\u3002<\/li>\n<li class=\"bana_03 sm_bana_02\"><span class=\"f1 blue\">\u2469 \u753b\u671f\u7684\u306a\u30a8\u30d4\u30b2\u30ce\u30e0\u5275\u85ac<\/span><br \/>\n\u6838\u9178\u3084\u30d2\u30b9\u30c8\u30f3\u306e\u5f8c\u5929\u7684\u4fee\u98fe\u306b\u304a\u3044\u3066\u3082\u3001\u30ef\u30f3\u30ab\u30fc\u30dc\u30f3\u4ee3\u8b1d\u306f\u91cd\u8981\u306a\u5f79\u5272\u3092\u62c5\u3063\u3066\u3044\u307e\u3059\u3002\u79c1\u9054\u306f\u6700\u65b0\u306e\u6280\u8853\u3092\u6d3b\u7528\u3057\u3066\u3001\u81e8\u5e8a\u5fdc\u7528\u3092\u76ee\u6307\u3057\u305f\u30a8\u30d4\u30b2\u30ce\u30e0\u5275\u85ac\u3092\u30b7\u30b9\u30c6\u30e0\u7684\u306b\u5c55\u958b\u3057\u3066\u3044\u307e\u3059\u3002\u7af6\u5408\u7684\u8cc7\u91d1\u3092\u5f97\u3066\u3001\u30a2\u30ab\u30c7\u30df\u30a2\u306b\u304a\u3051\u308b\u5275\u85ac\u3068\u80b2\u85ac\u3092\u9032\u3081\u3001\u7523\u5b66\u9023\u643a\u304b\u3089\u793e\u4f1a\u8ca2\u732e\u3092\u76ee\u6307\u3057\u3066\u3044\u307e\u3059\u3002\u5927\u962a\u5927\u5b66\u672a\u6765\u533b\u7642\u30bb\u30f3\u30bf\u30fc\u3067\u652f\u63f4\u3055\u308c\u3066\u3044\u307e\u3059\u3002<\/li>\n<li class=\"bana_03 sm_bana_02\"><span class=\"f1 blue\">\u246a \u672a\u6765\u578b\u533b\u7642\u306e\u5177\u73fe\u5316\u30d7\u30ed\u30b8\u30a7\u30af\u30c8<\/span><br \/>\n\u79c1\u9054\u306e\u7814\u7a76\u74b0\u5883\u3092\u6d3b\u304b\u3057\u305f\u4eba\u6750\u80b2\u6210\u3067\u672a\u6765\u306b\u6311\u6226\u3057\u3001\u793e\u4f1a\u9084\u5143\u3092\u76ee\u6307\u3057\u307e\u3059\u3002\u3053\u308c\u3089\u306f\u3001\u4e0a\u8a18\u306e\u7814\u7a76\u306e\u6210\u679c\u306e\uff11\u3064\u3067\u3059\u3002<\/p>\n<li class=\"bana_03 sm_bana_02\">1)\u3000\u30a4\u30f3\u30b7\u30ea\u30b3\u5275\u85ac\u652f\u63f4<br \/>\n\u69cb\u9020\u5316\u5b66\u306b\u3082\u3068\u3065\u304f\u30b7\u30b9\u30c6\u30e0\u5275\u85ac\u3092\u9032\u3081\u3066\u3044\u307e\u3059\uff08\u5c0f\u95a2\u3089\uff09\u3002\u69cb\u9020\u8a08\u7b97\u306b\u3088\u308b\u8010\u6027\u306e\u4e88\u6e2c\u3068\u514b\u670d\u6cd5\u306e\u958b\u767a\u3001\u305d\u306e\u30b5\u30d6\u30b0\u30eb\u30fc\u30d7\u533b\u7642\u3078\u306e\u5fdc\u3001\u3055\u3089\u306b\u306fC1\u4ee3\u8b1d\u3068\u3057\u3066\u6838\u9178\u30a2\u30ca\u30ed\u30b0\u306e\u7814\u7a76\u306b\u529b\u3092\u767a\u63ee\u3057\u3066\u3044\u307e\u3059\u3002\u5f93\u6765\u306e\u4ed6\u306e\u65b9\u6cd5\u306b\u6bd4\u8f03\u3057\u3066\u3001\u9ad8\u3044\u7cbe\u5ea6\u306e\u7d50\u679c\u304c\u3088\u308a\u77ed\u6642\u9593\u3067\u5f97\u3089\u308c\u3066\u3044\u307e\u3059\u3002<\/li>\n<li class=\"bana_03 sm_bana_02\">2)\u3000\u6a19\u7684\u767a\u898b<br \/>\n\u6cbb\u7642\u5fdc\u7b54\u3001\u4e88\u5f8c\u3001\u30b5\u30d6\u30b0\u30eb\u30fc\u30d7\u89e3\u6790\u7b49\u306e\u57fa\u790e\u7684\u81e8\u5e8a\u7684\u306e\u30c7\u30fc\u30bf\u89e3\u6790\u304b\u3089\u5f97\u3089\u308c\u305fDruggable Targets\u306b\u5bfe\u3057\u3066\u3001\u30a8\u30d4\u30b2\u30ce\u30e0\u5275\u85ac\u3092\u9032\u3081\u3066\u3044\u307e\u3059\uff08\u897f\u7530\u3089\uff09\u3002\u3055\u3089\u306b\u69cb\u9020\u5316\u5b66\u306b\u57fa\u3065\u304f\u5275\u85ac\u3001\u5408\u6210\u5c55\u958b\u3084\u65e2\u5b58\u5316\u5408\u7269\u306e\u518d\u8a55\u4fa1\uff08Structure-based Drug Repositioning\uff09\u3082\u9032\u3081\u3066\u3044\u307e\u3059\u3002\u3053\u308c\u3089\u306f\u6d88\u5316\u5668\u5916\u79d1\u3068\u604a\u50cd\u3057\u305f\u30a2\u30ab\u30c7\u30df\u30a2\u5275\u85ac\u3068\u3057\u3066\u5c55\u958b\u3057\u307e\u3059\u3002<\/li>\n<li class=\"bana_03 sm_bana_02\">3\uff09\u578b\u7834\u308a\u7814\u7a76<br \/>\nDNA\u306e\u60c5\u5831\u304c\u91cd\u8981\u3067\u3042\u308b\u3053\u3068\u306b\u306f\u304b\u308f\u308a\u3042\u308a\u307e\u305b\u3093\u304c\u3001\u75be\u60a3\u306e\u8868\u73fe\u578b\uff08\u30d5\u30a7\u30ce\u30bf\u30a4\u30d7\uff09\u3092\u898f\u5b9a\u3059\u308b\u306e\u306f\u3001\u30a8\u30d4\u30b2\u30ce\u30e0\u306e\u52b9\u679c\u3082\u5927\u304d\u3044\u3068\u8003\u3048\u3089\u308c\u3066\u3044\u307e\u3059\u3002\u3057\u304b\u3057\u3001\u305d\u306e\u5185\u5bb9\u306b\u306f\u672a\u77e5\u306e\u90e8\u5206\u304c\u6b8b\u3055\u308c\u3066\u304a\u308a\u3001\u305d\u306e\u4e2d\u306b\u306f\u30bb\u30f3\u30c8\u30e9\u30eb\u30c9\u30b0\u30de\u306e\u610f\u7fa9\u3084\u9069\u5fdc\u7bc4\u56f2\u306b\u8feb\u308b\u3082\u306e\u3082\u3042\u308a\u307e\u3059\u3002\u4f8b\u3048\u3070\u3001\u30b2\u30ce\u30e0\u306e\u60c5\u5831\u304cmRNA\u3068\u306a\u308a\u305d\u308c\u304c\u7ffb\u8a33\u3055\u308c\u308b\u524d\u306b\u3000\u66f8\u304d\u63db\u3048\u3089\u308c\u3066\u3044\u305f\u3089\u3069\u3046\u3067\u3057\u3087\u3046\u304b\u3002\u8fd1\u5e74\u306e\u7814\u7a76\u3067\u305d\u306e\u53ef\u80fd\u6027\u304c\u5c11\u3057\u305a\u3064\u660e\u3089\u304b\u306b\u306a\u3063\u3066\u304d\u307e\u3057\u305f\u3002\u4e0a\u3067\u8ff0\u3079\u305f\u6838\u9178\u306emodification \u3068editing\u306f\u5206\u3051\u3066\u8003\u3048\u308b\u5fc5\u8981\u304c\u3042\u308a\u307e\u3059\u3002\u4eca\u91ce\u3089\u306f\u3001A-to-I editing\u3084C-to-U\u3000editing\u3068\u30d2\u30c8\u75be\u60a3\u306e\u95a2\u9023\u6027\u3092non-coding editing\u3092\u4e2d\u5fc3\u306b\u3057\u3066\u30c7\u30fc\u30bf\u30b5\u30a4\u30a8\u30f3\u30b9\u3057\u3066\u3044\u307e\u3059\u3002\u3053\u308c\u3089\u306f\u3001\u764c\u306e\u8a3a\u65ad\u3060\u3051\u3067\u306a\u304f\u3001\u795e\u7d4c\u75be\u60a3\u306a\u3069\u306e\u96e3\u6cbb\u75be\u60a3\u306e\u89e3\u660e\u3067\u3082\u65b0\u5c55\u958b\u304c\u671f\u5f85\u3055\u308c\u307e\u3059\u3002\u6838\u9178\u30a2\u30ca\u30ed\u30b0\u3067\u3042\u308bTAS102\u306a\u3069\u306e\u52b9\u679c\u3082\u89e3\u6790\u3092\u9032\u3081\u3066\u3044\u307e\u3059\u3002<\/li>\n<li>4)\u3000\u30c7\u30fc\u30bf\u99c6\u52d5\u578b\u793e\u4f1a\u306e\u4eba\u6750\u80b2\u6210<br \/>\n\u73fe\u4ee3\u793e\u4f1a\u306e\u30c7\u30fc\u30bf\u5316\u306f\u3001\u731b\u30b9\u30d4\u30fc\u30c9\u3067\u9032\u3093\u3067\u3044\u307e\u3059\u3002\u305d\u306e\u5f71\u97ff\u306f\u3001\u751f\u547d\u79d1\u5b66\u3084\u533b\u5b66\u306e\u5206\u91ce\u3067\u3082\u4f8b\u5916\u3067\u306f\u3042\u308a\u307e\u305b\u3093\u3002\u6280\u8853\u9769\u65b0\u306f\u65b0\u3057\u3044\u7523\u696d\u9769\u547d\u306e\u539f\u52d5\u529b\u3068\u306a\u308a\u3001\u7523\u696d\u69cb\u9020\u3001\u52b4\u50cd\u4f53\u5236\u3001\u3055\u3089\u306b\u306f\u793e\u4f1a\u305d\u306e\u3082\u306e\u304c\u73fe\u5728\u306e\u72b6\u614b\u304b\u3089\u5927\u304d\u304f\u69d8\u5909\u308f\u308a\u3059\u308b\u53ef\u80fd\u6027\u304c\u6307\u6458\u3055\u308c\u3066\u3044\u307e\u3059\u3002\u305d\u306e\u5f71\u97ff\u306f\u3001\u76ee\u306b\u898b\u3048\u308b\u7269\u306e\u4e16\u754c\u3060\u3051\u3068\u306f\u9650\u3089\u305a\u3001\u4eba\u3005\u306e\u8003\u3048\u65b9\u3084\u5185\u306a\u308b\u5224\u65ad\u306b\u307e\u3067\u6d78\u900f\u3059\u308b\u3068\u3055\u308c\u3001\u305d\u308c\u3092\u6280\u8853\u7684\u306a\u7279\u7570\u70b9\uff08Singularity\uff09\u3068\u63d0\u5531\u30572045\u5e74\u9803\u306b\u5927\u5c40\u7684\u306a\u5909\u5316\u304c\u751f\u3058\u308b\u3067\u3042\u308d\u3046\u3068\u4e88\u6e2c\u3055\u308c\u3066\u3044\u307e\u3059\u3002\u653f\u5e9c\u3084\u6587\u90e8\u79d1\u5b66\u7701\u3082\u3053\u306e\u52d5\u5411\u3092\u6ce8\u8996\u3057\u3066\u3044\u307e\u3059\u3002\u79c1\u305f\u3061\u306f\u4ed6\u306e\u30a2\u30ab\u30c7\u30df\u30a2\u7814\u7a76\u5ba4\u3068\u604a\u50cd\u3057\u3066\u3001\u65b0\u6280\u8853\u3092\u7406\u89e3\u3057\u4eba\u5de5\u77e5\u80fd\uff08AI\uff09\u3084\u30b9\u30d1\u30b3\u30f3\u306b\u9055\u548c\u611f\u3092\u6301\u305f\u306a\u3044\u6b21\u4e16\u4ee3\u3092\u62c5\u3046\u82e5\u624b\u4eba\u6750\u3092\u80b2\u6210\u3059\u308b\u3053\u3068\u306b\u529b\u3092\u6ce8\u3044\u3067\u3044\u307e\u3059\uff08\u4eca\u91ce\u30fb\u6d45\u4e95\u30fb\u5c0f\u95a2\u3089\uff09\u3002\u3053\u306e\u30d3\u30b8\u30e7\u30f3\u306f\u3001\u4eba\u9593\u3068\u4f55\u306a\u306e\u304b\u3001\u533b\u7642\u4eba\u3068\u3057\u3066\u672c\u8cea\u7684\u304b\u3064\u6839\u672c\u7684\u306a\u7406\u89e3\u306b\u7e4b\u304c\u308b\u59ff\u52e2\u3068\u3057\u3066\u3001\u6b21\u4e16\u4ee3\u3092\u5207\u308a\u62d3\u304f\u4eba\u9593\u529b\u3092\u80b2\u3080\u3068\u671f\u5f85\u3055\u308c\u307e\u3059\u3002<\/li>\n<\/ul>\n<\/div>\n<p><!--\u3053\u3053\u304b\u3089\u82f1\u6587--><\/p>\n<h3 class=\"text-center h2 blue bold bana_05 sm_bana_04 other_lbl02\"><span>Projects<\/span><\/h3>\n<div>\n<p class=\"bana_03 sm_bana_02 blue f3\">Project for developing innovative advanced chemotherapy of gastrointestinal cancer by combining state of art medical technologies (Cancer Frontier Science Program)<\/p>\n<p>We developed integrated therapeutics that are unparalleled in the world for diseases with high unmet needs. For the treatment of highly intractable gastrointestinal cancer, which is not expected to be completely cured by conventional treatment, we actively challenged the concept of developing therapeutics, which has not been adopted by companies because of reasons such as high development risk. We applied strategic borderless combinations of immune, regeneration, and tumor systems to promote and expand innovative drug discovery and development through rapid clinical application by exploiting novel medical seeds that are appropriate for the next generation. Our strategic goal is to analyze abundant clinical information including super responders in detail for innovative seed discoveries and drug development. We aim to comprehensively contribute to the development of Japan as a science- and technology-oriented nation by facilitating the promotion of people&#8217;s health through the industry-academia collaboration.<\/p>\n<\/div>\n","protected":false},"excerpt":{"rendered":"<p>\u3010\u76ee\u6a19\u9054\u6210\u306e\u305f\u3081\u306e Headquarters\u3011 iLAB-HQ \u57fa\u5e79\u8b1b\u5ea7\u3068\u3057\u3066\u306e\u6d88\u5316\u5668\u5916\u79d1\u5b66\uff08\u571f\u5c90\u7950\u4e00\u90ce\u6559\u6388\u3001\u6c5f\u53e3\u82f1\u5229\u6559\u6388\uff09\u3068\u3068\u3082\u306b\u96e3\u6cbb\u75be\u60a3\u3001\u7279\u306b\u304c\u3093\u5e79\u7d30\u80de\u306e\u7814\u7a76\u3092\u63a8\u9032\u3057\u3001\u672c\u8b1b\u5ea7\u306e\u4e3b\u305f\u308b\u30df\u30c3\u30b7\u30e7\u30f3\u3068\u3057\u3066\u75be\u60a3\u30c7\u30fc\u30bf\u30b5\u30a4\u30a8\u30f3 &hellip; <a href=\"https:\/\/www.med.osaka-u.ac.jp\/pub\/mds\/projects\" class=\"more-link\"><span class=\"screen-reader-text\">&#8220;\u30d7\u30ed\u30b8\u30a7\u30af\u30c8&#8221; \u306e<\/span>\u7d9a\u304d\u3092\u8aad\u3080<\/a><\/p>\n","protected":false},"author":1,"featured_media":0,"parent":0,"menu_order":0,"comment_status":"closed","ping_status":"closed","template":"","meta":{"_acf_changed":false,"footnotes":""},"class_list":["post-398","page","type-page","status-publish","hentry"],"acf":[],"aioseo_notices":[],"_links":{"self":[{"href":"https:\/\/www.med.osaka-u.ac.jp\/pub\/mds\/wp-json\/wp\/v2\/pages\/398","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/www.med.osaka-u.ac.jp\/pub\/mds\/wp-json\/wp\/v2\/pages"}],"about":[{"href":"https:\/\/www.med.osaka-u.ac.jp\/pub\/mds\/wp-json\/wp\/v2\/types\/page"}],"author":[{"embeddable":true,"href":"https:\/\/www.med.osaka-u.ac.jp\/pub\/mds\/wp-json\/wp\/v2\/users\/1"}],"replies":[{"embeddable":true,"href":"https:\/\/www.med.osaka-u.ac.jp\/pub\/mds\/wp-json\/wp\/v2\/comments?post=398"}],"version-history":[{"count":61,"href":"https:\/\/www.med.osaka-u.ac.jp\/pub\/mds\/wp-json\/wp\/v2\/pages\/398\/revisions"}],"predecessor-version":[{"id":1466,"href":"https:\/\/www.med.osaka-u.ac.jp\/pub\/mds\/wp-json\/wp\/v2\/pages\/398\/revisions\/1466"}],"wp:attachment":[{"href":"https:\/\/www.med.osaka-u.ac.jp\/pub\/mds\/wp-json\/wp\/v2\/media?parent=398"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}