{"id":489,"date":"2015-07-21T11:06:17","date_gmt":"2015-07-21T02:06:17","guid":{"rendered":"https:\/\/www.med.osaka-u.ac.jp\/pub\/mds\/?p=489"},"modified":"2024-03-18T10:32:16","modified_gmt":"2024-03-18T01:32:16","slug":"prognostic-impact-of-peritumoral-il-17-positive-cells-and-il-17-axis-in-patients-with-intrahepatic-cholangiocarcinoma-annal-surg-oncology-2015","status":"publish","type":"post","link":"https:\/\/www.med.osaka-u.ac.jp\/pub\/mds\/archives\/489","title":{"rendered":"Prognostic impact of peritumoral IL-17-positive cells and IL-17 axis in patients with intrahepatic cholangiocarcinoma (Annal. Surg. Oncology, 2015)"},"content":{"rendered":"<p><strong><span style=\"font-family: Georgia, 'Times New Roman', Times, serif;\"><a href=\"http:\/\/link.springer.com\/article\/10.1245%2Fs10434-015-4782-y\" target=\"_blank\" rel=\"noopener\">Prognostic impact of peritumoral IL-17-positive cells and IL-17 axis in patients with intrahepatic cholangiocarcinoma\u00a0(Annal. Surg. Oncology, 2015)<\/a><\/span><\/strong><\/p>\n<p><span style=\"font-family: 'Times New Roman', Times, serif;\">In collaboration with the Department of Surgery, Osaka University (Profs. Masaki Mori and Yuichiro Doki), Asukai et al. studied the tumor immunology.\u00a0 Immunohistochemical analysis showed that the expression of IL-6, IL-17RA, and peritumoral IL-17A significantly correlated with a poor outcome. Further, high preoperative plasma levels of IL-6 in <\/span><span style=\"font-family: 'Times New Roman', Times, serif;\">patients with\u00a0cholangiocarcinoma (ICC)\u00a0corresponded with significantly shorter disease-free survival (DFS).\u00a0Our data suggested that IL-6, peritumoral IL-17 + \u00a0cells, and IL-17RA expression are postoperative useful markers for predicting recurrence in patients with ICC.<\/span><\/p>\n","protected":false},"excerpt":{"rendered":"<p>Prognostic impact of peritumoral IL-17-positive cells and IL-17 axis in patients with intrahepatic cholangioca &hellip; <a href=\"https:\/\/www.med.osaka-u.ac.jp\/pub\/mds\/archives\/489\" class=\"more-link\"><span class=\"screen-reader-text\">&#8220;Prognostic impact of peritumoral IL-17-positive cells and IL-17 axis in patients with intrahepatic cholangiocarcinoma (Annal. Surg. Oncology, 2015)&#8221; \u306e<\/span>\u7d9a\u304d\u3092\u8aad\u3080<\/a><\/p>\n","protected":false},"author":1,"featured_media":0,"comment_status":"closed","ping_status":"closed","sticky":false,"template":"","format":"standard","meta":{"footnotes":""},"categories":[17],"tags":[],"class_list":["post-489","post","type-post","status-publish","format-standard","hentry","category-results"],"aioseo_notices":[],"acf":[],"_links":{"self":[{"href":"https:\/\/www.med.osaka-u.ac.jp\/pub\/mds\/wp-json\/wp\/v2\/posts\/489","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/www.med.osaka-u.ac.jp\/pub\/mds\/wp-json\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/www.med.osaka-u.ac.jp\/pub\/mds\/wp-json\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/www.med.osaka-u.ac.jp\/pub\/mds\/wp-json\/wp\/v2\/users\/1"}],"replies":[{"embeddable":true,"href":"https:\/\/www.med.osaka-u.ac.jp\/pub\/mds\/wp-json\/wp\/v2\/comments?post=489"}],"version-history":[{"count":3,"href":"https:\/\/www.med.osaka-u.ac.jp\/pub\/mds\/wp-json\/wp\/v2\/posts\/489\/revisions"}],"predecessor-version":[{"id":1742,"href":"https:\/\/www.med.osaka-u.ac.jp\/pub\/mds\/wp-json\/wp\/v2\/posts\/489\/revisions\/1742"}],"wp:attachment":[{"href":"https:\/\/www.med.osaka-u.ac.jp\/pub\/mds\/wp-json\/wp\/v2\/media?parent=489"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/www.med.osaka-u.ac.jp\/pub\/mds\/wp-json\/wp\/v2\/categories?post=489"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/www.med.osaka-u.ac.jp\/pub\/mds\/wp-json\/wp\/v2\/tags?post=489"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}