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HOME ＞ 研究成果概要・研究業績 ＞ 研究業績 ： 計画研究05
研究業績

計画研究05

器官・組織形成期の発生異常に基づく上皮管腔組織形成障害
研究概要
研究成果概要
研究代表者： 大谷 浩
研究分担者： 八田 稔久
研究分担者： 宇田川 潤

英文原著論文

  • Motoya, T., Ogawa, N., Nitta, T., Rafiq, A.M., Jahan, E., Furuya, M., Matsumoto, A., Udagawa, J., Otani, H. Interkinetic nuclear migration in the mouse embryonic ureteric epithelium: Possible implication for congenital anomalies of the kidney and urinary tract. Congenit. Anom., (in press).
  • Tsukada, T., Simamura, E., Shimada, H., Arai, T., Higashi. N., Akai, T., Iizuka, H., Hatta, T. The suppression of maternal-fetal leukemia inhibitory factor signal relay pathway by maternal immune activation impairs brain development in mice. PLos One, (in press).
  • Nakata, H., Wakayama, T., Sonomura, T., Honma, S., Hatta, T., Iseki, S. Three-dimensional structure of seminiferous tubules in the adult mouse. J. Anat., (in press).
  • Fujiyama, F., Nakano, T., Matsuda, W., Furuta, T., Udagawa, J., Kaneko, T. A single-neuron tracing study of arkypallidal and prototypic neurons in healthy rats. Brain Struct. Funct., (in press).
  • Simamura, E., Arikawa, T., Ikeda, T., Shimada, H., Shoji, H., Masuta, H., Nakajima, Y., Otani, H., Yonekura, H., Hatta, T. Melanocortins contribute to sequential differentiation and enucleation of human erythroblasts via melanocortin receptors 1, 2 and 5. PLos One 10:1-17, 2015.
  • Okano, J., Kojima, H., Katagi, M., Nakae, Y., Terashima, T., Nakagawa, T., Kurakane, T., Okamoto, N., Morohashi, K., Maegawa, H., Udagawa, J. Epidermis-dermis junction as a novel location for bone marrow-derived cells to reside in response to ionizing radiation. Biochem. Biophys. Res. Commun. 12;461:695-701, 2015.
  • Sugiura, S., Tazuke, M., Ueno, S., Sugiura, Y., Kato, I., Miyahira, Y., Yamamoto, Y., Sato, H., Udagawa, J., Uehara, M., Sugiura, H. Effect of prolactin-induced protein on human skin: new insight into the digestive action of this aspartic peptidase on the stratum corneum and its induction of keratinocyte proliferation. J. Invest. Dermatol. 153:776-785, 2015.
  • Naito, K., Notsu, A., Udagawa, J., Otani, H. Statistical analysis with dilatation for development process of human fetuses. Stat. Methods Med. Res. 2014 Jul 22 pii: 0962280214543405.
  • Nishita, M., Qiao, S., Miyamoto, M., Okinaka, Y., Yamada, M., Hashimoto, R., Iijima, K., Otani, H., Hartmann, C., Nishinakamura, R., Minami, Y. Role of Wnt5a-Ror2 signaling in morphogenesis of the metanephric mesenchyme during ureteric budding. Mol. Cell. Biol. 34: 3096-3105, 2014.
  • Jahan, E., Matsumoto, A., Rafiq, A.M., Hashimoto, R., Inoue, T., Udagawa, J., Sekine, J., Otani, H. Fetal jaw movement affects Ihh signaling in mandibular condylar cartilage development: The possible role of Ihh as mechanotransduction mediator. Arch. Oral. Biol. 59: 1108-1118, 2014.
  • Inoue, T., Hashimoto, R., Matsumoto, A., Jahan, E., Rafiq, A.M., Udagawa, J., Hatta, T., Otani, H. In vivo analysis of Arg-Gly-Asp sequence/integrin α5β1-mediated signal involvement in embryonic enchondral ossification by exo utero development system. J. Bone Miner. Res. 91: 119-127, 2014.
  • Tatsumi, H., Hideshima, H., Kanno, T., Hashimoto, R., Matsumoto, A., Otani, H., Sekine, J. Effect of ageing on healing of bilateral mandibular condyle fractures in a rat model. Int. J. Oral Maxillofac. Surg. 43: 185-193, 2014.
  • Arikawa, T., Simamura, E., Shimada, H., Nakamura, T., Hatta. T., and Shoji, H. Significance of sugar chain recognition by galectins and its involvement in disease-associated glycosylation. Congenit. Anom. 54: 77-81, 2014.
  • Katagi, M., Terashima, T., Okano, J., Urabe, H., Nakae, Y., Ogawa, N., Udagawa, J., Maegawa, H., Matsumura, K., Chan, L., Kojima, H. Hyperglycemia induces abnormal gene expression in hematopoietic stem cells and their progeny in diabetic neuropathy. FEBS Lett. 588: 1080-1086, 2014.
  • Okano, J., Udagawa, J., Shiota, K. Roles of retinoic acid signaling in normal and abnormal development of the palate and tongue. Congenit. Anom. 54: 69-76, 2014.
  • Hashimoto, R., Matsumoto, A., Udagawa, J., Hioki, K., Otani, H. Effect of leptin administration on myelination in ob/ob mouse cerebrum after birth. NeuroReport 24: 22-29, 2013.
  • Yamada, M., Udagawa, J., Hashimoto, R., Matsumoto, A., Hatta, T., Otani, H. Interkinetic nuclear migration during early development of midgut and ureteric epithelia. Anat. Sci. Int. 88: 31-37, 2013.
  • Liang, S., Tanabe, K., Niu, Y., Otani, H. Histological changes in the developing heart of human fetuses. Shimane J. Med. Sci. 30: 1-10, 2013.
  • Arikawa, T., Simamura, E., Shimada, H., Nishi, N., Tatsuno, T., Ishigaki, Y., Tomosugi, N., Yamashiro, C., Hata, T., Takegami, T., Mogami, H., Yamaguchi, K., Nakamura, T., Otani, H., Hatta, T., Shoji, H. Expression pattern of Galectin 4 in rat placentation. Placenta 33: 885-887, 2012.
  • Rafiq, A.M., Udagawa, J., Lundth, T., Jahan, E., Matsumoto, A., Sekine, J., Otani, H. Mathematical analysis of mandibular morphogenesis by micro-CT-based mouse and alizarin red S-stained-based human studies during development. Anat. Rec. 295: 313-327, 2012.
  • Hashimoto, R., Udagawa, J., Kagohashi, Y., Matsumoto, A., Hatta, T., Otani, H. Direct and indirect effects of neuropeptide Y and neurotrophin 3 on myelination in the neonatal brains. Brain Res. 1373: 55-66, 2011.
  • Lundh, T., Udagawa, J., Hänel, S.E., Otani, H. Cross- and triple-ratios of human body parts during development. Anat. Rec. 294: 1360-1369, 2011.
  • Kawamoto, M., Udagawa, J., Hashimoto, R., Matsumoto, A., Yamada, M., Nimura, M., Otani, H. Adrenocorticotropic tumor cells transplanted into mouse embryos affect pancreatic histogenesis. Congenit. Anom. 51: 62-69, 2011.
  • Zhang, Q., Wang, H., Udagawa, J., Otani, H. Morphological and morphometric study on sphenoid and basioccipital ossification in normal human fetuses. Congenit. Anom. 51: 138-148, 2011.
  • Matsumoto, A., Hatta, T., Ono, A., Hashimoto, R., Otani, H. Stage-specific changes in the levels of granulocyte-macrophage colony-stimulating factor and its receptor in the biological fluid and organ of mouse fetuses. Congenit. Anom. 51: 183-186, 2011.

英文総説

  • Otani, H., Udagawa, J., Naito, K. Statistical analyses in trials for the comprehensive understanding of organogenesis and histogenesis in humans and mice. J. Biochem., (in press).
  • Kagohashi, Y., Otani, H. Role of nutritional factors at the early life stages in the pathogenesis and clinical course of type 1 diabetes. Biomed. Res. Int., (in press).
  • Jahan, E., Rafiq, A.M., Otani, H. In utero and exo utero fetal surgery on histogenesis of organs in animals. World J. Surg. Proced. 5:198-207, 2015.
  • Simamura, E., Shimada, H., Shoji, H., Otani, H., Hatta, T. Effects of melanocortins on fetal development. Congenit. Anom. 51: 47-54, 2011.

和文総説

  • 大谷　浩：　ヒト・マウスの器官形成と組織形成における正常と異常：日本周産期・新生児医学会雑誌　50巻4号: 1153-1155, 2015
  • 大谷　浩：　上皮管腔組織の器官形成と組織形成の解析：島根医学　33巻4号：170-179, 2013
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