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平成24〜25年度： 公募研究13
神経上皮組織の自己組織的な形態形成の基盤となる細胞骨格動態の解明
英文原著論文
- Imuta, Y., Koyama, H., Shi, D., Eiraku, M., Fujimori, T., Sasaki, H. Mechanical control of notochord morphogenesis by extra-embryonic tissues in mouse embryos. Mech. Dev., (in press).
- Kadoshima, T., Sakaguchi, H., Nakano, T., Soen, M., Ando, S., Eiraku, M., Sasai, Y. Self-organization of axial polarity, inside-out layer pattern, and species-specific progenitor dynamics in human ES cell-derived neocortex. Proc. Natl. Acad. Sci. USA. 110(50): 20284-20289, 2013.
- Okuda, S., Inoue, Y., Eiraku, M., Sasai, Y., Adachi, T. Apical contractility in growing epithelium supports robust maintenance of smooth curvatures against cell-division-induced mechanical disturbance. J. Biomech. 46(10): 1705-1713, 2013.
- Nasu, M., Takata, N., Danjo, T., Sakaguchi, H., Kadoshima, T., Futaki, S., Sekiguchi, K., Eiraku, M., Sasai, Y. Robust formation and maintenance of continuous stratified cortical neuroepithelium by laminin-containing matrix in mouse ES cell culture. PLoS One 7(12): e53024, 2012.
- Okuda, S., Inoue, Y., Eiraku, M., Sasai, Y., Adachi, T. Modeling cell proliferation for simulating three-dimensional tissue morphogenesis based on a reversible network reconnection framework. Biomech. Model. Mechanobiol., 2012.
- Okuda, S., Inoue, Y., Eiraku, M., Sasai, Y., Adachi, T. Reversible network reconnection model for simulating large deformation in dynamic tissue morphogenesis. Biomech. Model. Mechanobiol., 2012.
- Nakano, T., Ando, S., Takata, N., Kawada, M., Muguruma, K., Sekiguchi, K., Saito, K., Yonemura, S., Eiraku, M., Sasai, Y. Self-formation of optic cups and storable stratified neural retina from human ESCs. Cell Stem Cell 10(6): 771-785, 2012.
- Eiraku, M., Sasai, Y. Mouse embryonic stem cell culture for generation of three-dimensional retinal and cortical tissues. Nat. Protoc. 7(1): 69-79, 2011.
- Eiraku, M., Adachi, T., Sasai, Y. Relaxation-expansion model for self-driven retinal morphogenesis: a hypothesis from the perspective of biosystems dynamics at the multi-cellular level. Bioessays. 34(1): 17-25, 2012.
英文総説
- Sasai Y, Eiraku, M., Suga, H. In vitro organogenesis in three dimensions: self-organising stem cells. Development. 139(22): 4111-4121, 2012.
- Eiraku, M., Sasai, Y. Self-formation of layered neural structures in three-dimensional culture of ES cells. Curr. Opin. Neurobiol. 22(5): 768-777, 2012.
和文総説
- 永楽 元次： 多能性幹細胞からの自律的な立体網膜組織形成：実験医学「再生できる・できない生物 その差から挑む三次元再生と再生医療」、32巻1号、42-48、2014
- 永楽 元次： in vitro分化誘導の原理：生物科学の遺伝「iPS細胞／ES細胞の生物学」、68巻1号、58-63、2014
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平成24〜25年度： 公募研究11へ
