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平成26〜27年度: 公募研究02

de novo管腔形成の制御機構
研究代表者: 松本 邦弘

英文原著論文

  • Alam, T., Maruyama, H., Li, C., Pastuhov, S., Nix, P., Bastiani, M., Hisamoto, N., Matsumoto, K. Axotomy-induced HIF-serotonin signaling axis promotes axon regeneration in C. elegans. Nature Commun. 10: e10388, 2016.
  • Morioka, S., Sai, K., Omori, E., Ikeda, Y., Matsumoto, K., Ninomiya-Tsuji, J. TAK1 regulates hepatic lipid homeostasis through SREBP. Oncogene 2016, (in press).
  • Fukuzono, T., Pastuhov, S., Fukushima, O., Li, C., Hattori, A., Iemura, S., Natsume, T., Shibuya, H., Hanafusa, H., Matsumoto, K., Hisamoto, H. The chaperone complex BAG2-HSC70 regulates localization of C. elegans Leucine-rich repeat kinase LRK-1 in the Golgi. Genes Cells 2016, (in press).
  • Hanafusa, H., Kedashiro, S., Tezuka, M., Funatsu, M., Usami, S., Toyoshima, F., Matsumoto, K. PLK1-dependent activation of LRRK1 regulates spindle orientation by phosphorylating CDK5RAP2. Nature Cell Biol. 17: 1024-1035, 2015.
  • Li, C., Hisamoto, N., Matsumoto, K. Axon regeneration is regulated by Ets-C/EBP transcription complexes generated by activation of the cAMP/Ca2+ signaling pathways. PLoS Genet. 11: e1005603, 2015.
  • Kedashiro, S., Pastuhov, S., Nishioka, T., Watanabe, W., Kaibuchi, K., Matsumoto, K., Hanafusa, H. Phosphorylation of CLIP-170 by LRRK1 regulates EGFR trafficking by promoting recruitment of p150-Glued to MT plus-ends. J. Cell Sci. 128: 385-396, 2015.
  • Hisamoto, N., Li, C., Yoshida, M., Matsumoto, K. The C. elegans HGF/plasminogen-like protein SVH-1 has protease-dependent and -independent functions. Cell Rep. 9: 1628-1634, 2014.
  • Morioka, S., Broglie, P., Omori, E., Ikeda, Y., Takaesu, G., Matsumoto, K., Ninomiya-Tsuji, J. TAK1 kinase switches cell fate from apoptosis to necrosis following TNFα stimulation. J. Cell. Biol. 204: 607-623, 2014.
  • Ikeda, Y., Morioka, S., Matsumoto, K., Ninomiya-Tsuji, J. TAK1 binding protein 2 is essential for liver protection from stressors. PLoS One 9: e88073, 2014.

英文総説

  • Hanafusa, H., Matsumoto, K. LRRK1 regulates spindle orientation downstream of PLK1 by phosphorylating CDK5RAP2. Cell Cycle 14: 3349-3350, 2015.
  • Pastuhov, S. Iv., Hisamoto, N., Matsumoto, K. MAP kinase cascades regulating axon regeneration in C. elegans. Proc. Japan Acad. Ser. B 91: 63-75, 2015.

和文総説

  • 花房 洋、松本 邦弘: ROCOファミリーキナーゼLRRK1によるEGFR細胞内トラフィック制御:実験医学(増刊)、33巻10号、18-23、2015