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Chairman Noriyuki Tomiyama

Diagnostic and Interventional Radiology

Radiology is a physical science that uses images to extract biological information and give diagnosis. Extraordinary advances in technology and computer science have added to the field’s importance. The lab focuses on diagnostic and interventional radiology (IVR), which aims to diagnose and treat the organs of the whole body.

The use of CT and MRI to study pathologies and other clinical applications

Osaka University is developing and applying the latest in CT and MRI technology for innovative imaging diagnostic equipment. One example is the clinical application of low dose CT using successive approximation methods. Figure 1 shows a CT image taken at 0.05 mSv (chest Xp) radiation dose. Details in the lung field cannot be resolved using conventional reconstruction methods (A in Figure 1), but microvessels in the peripheral lung can also be analyzed using our successive newly developed iterative reconstruction method (D in Figure 1).

Figure1 Submillisievert CT images using model-based iterative reconstruction

4D flow imaging with MRI combines the 3D imaging of MRI with electrocardiograms gating. This imaging makes it possible to observe blood flow with the cardiac cycle and could be visualized to intra cerebral aneurysms flow-lines (Figure 2). This imaging would make it possible to observe blood flow with the cardiac cycle and could be used to predict the risk of cerebral aneurysms rupture (Figure 2).

Figure2 Flow-imaging using MRI at intracranial basilar top aneurysm