Tsujimoto, Y. and Shimizu, S.: Bcl-2 family: Life-or-death switch, FEBS lett. 466: 6-10, 2000

Shimizu, Y. and Tsujimoto, Y.: Pro-apoptotic BH3-only Bcl-2 family members induce cytochrome c release, but not mitochondrial membrane potential loss, and do not directly modulate VDAC activity. Proc. Natl. Acad. Sci. USA. 97: 577-582, 2000

Sato, K., Eguchi, Y., Kodama, T. and Tsujimoto, Y.: Regions essential for the interaction between Bcl-2 and SMN, the spinal muscular atrophy disease gene product. Cell Death & Diff. 7: 374-383, 2000

Shimizu, S., Konishi, A., Kodama, T. and Tsujimoto, Y.: BH4 domain of anti-apoptotic Bcl-2 family members closes VDAC, and inhibits apoptotic mitochondrial changes and cell death. Proc. Natl. Acad. Sci. USA. 97: 3100-3105, 2000

Ueno, H., Kondo, E., Yamamoto-Honda, R., Tobe, K., Nakamoto, T., Sasaki, K., Mitani, K., Furusaka, A., Tanaka, T., Tsujimoto, Y., Kadowaki, T. and Hirai, H.: Association of insulin receptor substrate proteins with Bcl-2 and their effects on its phosphorylation and antiapoptotic function.. Mol. Biol. Cell, 11: 735-746, 2000

Shimizu, S., Ide, T., Yanagida, T. and Tsujimoto, Y. : Electrophysiological study of a novel large pore formed by Bax and VDAC, which is permeable to cytochrome c. J. Biol. Chem. 275: 12321-12325, 2000

Koya, R. C., Fujita, H., Shimizu, S., Ohtsu, M., Takimoto, M., Tsujimoto, Y. and Kuzumaki, N. Gelsolin inhibits apoptosis by blocking mitochondrial membrane potential loss and cytochrome c release. J. Biol. Chem. 275: 15343-15349

Tsujimoto, Y. Role of anti-apoptotic Bcl-2 protein in spinal muscular atrophy. J. Neural Transm. Suppl. 58: 41-52, 2000

Shimizu, S., Shinohara, Y. and Tsujimoto, Y. Bax and Bcl-xL independently regulate apoptotic changes of yeast mitochondria that require VDAC but not adenine nucleotide translocator. Oncogene 19: 4309-4318, 2000

Kusano, H., Shimizu, S., Koya, R.-C., Fujita, H., Kamada, S., Kuzumaki, N. and Tsujimoto, Y. Human gelsolin prevents apoptosis by inhibiting apoptotic mitochondrial changes via closing VDAC. Oncogene 19: 4807-4814, 2000

Tagami, S., Eguchi, Y., Kinoshita, M., Takeda, M. and Tsujimoto, Y. A novel protein, RTN-xs, interacts with both Bcl-xL and Bcl-2 on endoplasmic reticulum and reduces their anti-apoptotic activity. Oncogene 19: 5736-5746, 2000

Tsujimoto, Y. and Shimizu, S. VDAC regulation by the Bcl-2 family of proteins. Cell Death Diff. 7: 1174-1181, 2000