Hypoxia stimulates the cytoplasmic localization of oncogenic long noncoding RNA LINC00152 in colorectal cancer (Int J Oncol, in press)
In collaboration with the Department of Surgery, Osaka University (Profs. Masaki Mori and Yuichiro Doki), Nishizawa et al. demonstrated a long noncoding RNA, LINC00152, plays a pivotal role in cellular processes of colorectal cancer cells via the cytoplasmic localization under hypoxic tumor microenvironment. The present study indicated that lncRNA networks could provide diagnostic tools and novel therapeutic targets.