Figure 1. A schematic model of the IL-6 receptor system.

Both IL-6Ra and gp130 belong to the type I cytokine receptor family. Gp130 has regions (box1 and box2) that are conserved within the family and six tyrosines in its cytoplasmic domain.

大阪大学医学部ホームページへ戻る Osaka University Medical School

腫瘍病理ホームページへ戻る Hirano's Lab home page