RESULTS

Computational trans-omics approach characterised methylomic and transcriptomic involvements and identified novel therapeutic targets for chemoresistance in gastrointestinal cancer stem cells (Scientific Reports, 2018, in press)

In collaboration with the Department of Surgery, Osaka University (Profs. Masaki Mori and Yuichiro Doki), Konno et al. demonstrated by the computational trans-omics approach that the novel therapeutic targets are involved in the chemoresistance in gastrointestinal cancer stem cells. This mathematical method can be used to simultaneously quantify and identify chemoresistant potential targets in gastrointestinal cancer stem cells.