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<ひとことナビ> 過去の英文業績集です。【1992-1994】【1995-1997】【1998-2000】【2001-2003】【2004-】

新着情報　　　　　研究内容　　　　　教室員　　　　　業績集

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2001

  1. K. Sasai, Y. Ikeda, T. Tsuda, H. Ihara, H. Korekane, K. Shiota and N. Taniguchi: The critical role of the stem region as a functional domain responsible for the oligomerization and Golgi localization of N-acetylglucosaminyltransferase V: The involvement of a domain homophilic interaction. , J. Biol. Chem.,276:267-274, 2001.
  2. T. Kitada, E. Miyoshi, K. Noda, S. Higashiyama, H. Ihara, N. Matsuura, N. Hayashi, S. Kawata, Y. Matsuzawa and N. Taniguchi: The Addition of bisecting N-acetylglucosamine residues to E-cadherin downregulates the tyrosine phosphorylation of beta-catenin. , J. Biol. Chem.,276:475-480, 2001.
  3. K. Honke, M. Tsuda, S. Koyota, Y. Wada, T. N. Iida, I. Ishizuka, J. Nakayama and N. Taniguchi: Molecular Cloning And Characterization of A Human beta-Gal 3'-Sulfotransferase Which Acts on Both Type 1 and Type 2 (Galbeta1,3/1,4GlcNAc-R) Oligosaccharides. , J. Biol Chem., 276:759-765, 2001.
  4. K. Hisamoto, M. Ohmichi, H. Kurachi, J. Hayakawa, Y. Kanda, Y. Nishio, K. Adachi, K. Tasaka, E. Miyoshi, N. Fujiwara, N. Taniguchi and Y. Murata: Estrogen induces the Akt-dependent activation of endothelial nitric oxide synthase in vascular endothelial cells. , J. Biol. Chem., 276: 3459-3467, 2001.
  5. Y. H. Koh, K. Suzuki, W. Che, Y. S. Park, Y. Miyamoto, S. Higashiyama and N. Taniguchi: Inactivation of glutathione peroxidase by NO leads to the accumulation of H2O2 and the induction of HB-EGF via c-Jun NH2-terminal kinase in rat aortic smooth muscle cells. FASEB J. 15(8):1472-4, 2001.
  6. Y. Sato, M. Takahashi, Y. Shibukawa, S. K. Jain, R. Hamaoka, J. Miyagawa, Y. Yaginuma, K. Honke, M. Ishikawa and N. Taniguchi: Overexpression of N-acetylglucosaminyltransferase III enhances the EGF-induced phosphorylation of ERK in HeLaS3 cells by upregulation of the internalization rate of the receptors. J. Biol. Chem.13;276(15):11956-62, 2001.
  7. N. Taniguchi, A. Ekuni, J. H. Koh, E. Miyoshi, Y. Ikeda, Y. Ihara, A. Nishikawa, K. Honke, M. Takahashi: A glycomic approach to the identification and characterization of glycoprotein function in cells transfected with glycosyltransferase genes. Proteomics. Feb;1(2):239-47, 2001.
  8. T. Fujii, J. Fujii, and N. Taniguchi: Augmented expression of peroxiredoxinVI in rat lung and kidney after birth implies an antioxidative role. Eur. J. Biochem., 268: 218-224, 2001.
  9. W. Wang, W. Li, Y. Ikeda, J. Miyagawa, M. Taniguchi, E. Miyoshi, Y. Sheng, A. Ekuni, J. H. Ko, Y. Yamamoto, T. Sugimoto, S. Yamashita, Y. Matsuzawa, G. A. Grabowski, K. Honke and T. Taniguchi: Ectopic expression of a1,6 fucosyltransferase in mice causes steatosis in the liver and kidney accompanied by a modification of lysosomal acid lipase. , Glycobiology, 11, 165-174, 2001.
  10. T. Saito, A. Kinoshita, K. K. Yoshiura, Y. Makita, K. Wakui, K. Honke, N. Niikawa and N. Taniguchi: Domain-specific Mutations of a Transforming Growth Factor (TGF)-b1 Latency-associated Peptide Cause Camurati-Engelmann Disease Because of the Formation of a Constitutively Active Form of TGF-b1. , J. Biol. Chem., 276, 11469-11472, 2001.
  11. N. Sakata, N. Uesugi, S. Takebayashi, R. Nagai, T. Jono, S. Horiuchi, M. Takeya, H. Itabe, T. Takano, T. Myint and N. Taniguchi: Glycoxidation and lipid peroxidation of low-density lipoprotein can synergistically enhance atherogenesis. , Cardiovasc Res., 49, 466-75, 2001.
  12. N. Fujiwara, T. Fujii, J. Fujii and N. Taniguchi: Roles of n-terminal active cysteines and c-terminal cysteine-selenocysteine in the catalytic mechanism of mammalian thioredoxin reductase. , J. Biochem., 129, 803-12, 2001.
  13. R. J. Castellani, P. L. Harris, L. M. Sayre, J. Fujii, N. Taniguchi, M. P. Vitek, H. Founds, C. S. Atwood, G. Perry and M. A. Smith: Active glycation in neurofibrillary pathology of Alzheimer disease: N(varepsilon)-(Carboxymethyl) lysine and hexitol-lysine. Free Radic Biol Med. 15;31(2):175-80, 2001.
  14. T. Fujii, K. Mori, Y. Takahashi, N. Taniguchi, A. Tonosaki, H. Yamashita and J. Fujii: Immunohistochemical study of glutathione reductase in rat ocular tissues at different developmental stages. Histochem J. 33(5):267-72, 2001.
  15. K. Hisamoto, M. Ohmichi, Y. Kanda, K. Adachi, Y. Nishio, J. Hayakawa, S. Mabuchi, K. Takahashi, K. Tasaka, Y. Miyamoto, N. Taniguchi and Y. Murata: Induction of endothelial nitric oxide synthase phosphorylation by the raloxifene analog LY117018 is differentially mediated by Akt and extracellular signal-regulated protein kinase in vascular endothelial cells. J. Biol. Chem. in press.
  16. N. Ikeda, H. Eguchi, S. Nishihara, H. Narimatsu, R. Kannagi, T. Irimura, M. Ohta, H. Matsuda, N. Taniguchi and K. Honke: A remodeling system of the 3'-sulfo-Lewis a and 3'-sulfo-Lewis x epitopes. J. Biol. Chem. 276(42):38588-94, 2001.
  17. Y. H. Koh, W. Che, S. Higashiyama, M. Takahashi, Y. Miyamoto, K. Suzuki and N. Taniguchi: Osmotic Stress Induces HB-EGF Gene Expression via Ca(2+)/Pyk2/JNK Signal Cascades in Rat Aortic Smooth Muscle Cells. J. Biochem.130(3):351-8, 2001.
  18. S. Koyota, Y. Ikeda, S. Miyagawa, H. Ihara, M. Koma, K. Honke, R. Shirakura and N. Taniguchi: Down-regulation of the alpha-Gal epitope expression in N-glycans of swine endothelial cells by transfection with the N-acetylglucosaminyltransferase III gene. Modulation of the biosynthesis of terminal structures by a bisecting GlcNAc. J. Biol. Chem. 276(35):32867-74, 2001.
  19. V. V. Shuvaev, I. Laffont, J. M. Serot, J. Fujii, N. Taniguchi and G. Siest: Increased protein glycation in cerebrospinal fluid of Alzheimer's disease. Neurobiol. Aging. 22(3):397-402, 2001.

2002

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  1. H. Ihara, Y. Ikeda, S. Koyota, T. Endo, K. Honke, and N. Taniguchi: A catalytically inactive beta1,4-N-acetylglucosaminyltransferase III (GnT-III) behaves as a dominant negative GnT-III inhibitor. Eur. J. Biochem., 269(1), 193-201, 2002.
  2. Y. Tsuruta, A. Furuta, N. Taniguchi, T. Yamada, J. Kira and T. Iwaki: Increased expression of manganese superoxide dismutase is associated with that of nitrotyrosine in myopathies with rimmed vacuoles. Acta Neuropathol (Berl)., 103(1), 59-65. 2002.
  3. H. Eguchi, Y. Ikeda, S. Koyota, K. Honke, K. Suzuki, J.M.C. Gutteridge, and N. Taniguchi: Oxidative Damage Due to Copper Ion and Hydrogen Peroxide Induces GlcNAc-Specific Cleavage of an Asn-Linked Oligosaccharide. J. Biochem. 131, 477-484, 2002.
  4. M. Xian, N. Fujiwara, Z. Wen, T. Cai, S. Kazuma, A. J. Janczuk, X. Tang, V. V. Telyatnikov, Y. Zhang, X. Chen, Y. Miyamoto, N. Taniguchi and Wang, P. G.: Novel Substrates for Nitric Oxide Synthases. Bioorg. Med. Chem., 10, 3049-3055, 2002.
  5. A. Ekuni, E. Miyoshi, Ko, J. H., K. Noda, T. Kitada, S. Ihara., T. Endo, A. Hino, K. Honke, and N. Taniguchi: A glycomic approach to hepatic tumors in N-acetylglucosaminyltransferase III (GnT-III) transgenic mice induced by diethylynitorsamine (DEN): Identification of haptoglogin as a target molecule of GnT-III. Free Rad. Res., 36, 827-833, 2002.
  6. K. Honke, Y. Hirahara, J. Dupree, K. Suzuki, B. Popko, K. Fukushima, J. Fukushima, T. Nagasawa, N. Yoshida, Y. Wada and N. Taniguchi: Paranodal junction formation and spermatogenesis require sulfoglycolipids. Proc. Natl. Acad. Sci. USA, 99(7), 4227-4232, 2002.
  7. S. Ihara, E. Miyoshi, J. H. Ko, K. Murata, S. Nakahara, K. Honke, R. B. Dickson, C. Y. Lin, and N. Taniguchi: Pro-metastatic effect of N-acetylglucosaminyltransferase V is due to modification and stabilization of active matriptase by adding beta 1-6 GlcNAc-branching. J. Biol. Chem., 277(19), 16960-16967, 2002.
  8. I. Laffont, M. Takahashi, Y. Shibukawa, K. Honke, V. V. Shuvaev, G. Siest, S. Visvikis, and N. Taniguchi: Apolipoprotein E activates Akt pathway in neuro-2a in an isoform-specific manner. Biochem. Biophys. Res. Commun., 292(1), 83-87, 2002.
  9. K. Honke and N. Taniguchi: Sulfotransferases and Sulfated Oligosaccharides. Medical Research Reviews, 22, 637-654, 2002.
  10. M. Koma, S. Miyagawa, K. Honke, R. Nakai, S. Miyoshi, M. Ohta, H. Matuda, R. Shirakura and N. Taniguchi: The possibility of reducing xenoantigen levels by a novel Gal 3'-Sulfotransferase (GP3ST). J. Biochem. 133(4), 517-522, 2002.
  11. T. Saito, E. Miyoshi, K. Sasai, N. Nakano, H. Eguchi, K. Honke and N. Taniguchi: A secreted type of beta1,6-N-acetylglucosaminyltransferase V (GnT-V) induces tumor angiogenesis without mediation of glycosylation; -A novel function of GnT-V distinct from the original glycosyltransferase activity- J. Biol. Chem., 277(19), 17002-17008, 2002.
  12. YS. Park, N. Fujiwara, YH. Koh, Y. Miyamoto, K. Suzuki, K. Honke, N. Taniguchi: Induction of thioredoxin reductase gene expression by peroxynitrite in human umbilical vein endothelial cells. Biol Chem. 383(3-4), 683-91, 2002.
  13. K. Sasai, Y. Ikeda,T. Fujii, T. Tsuda, N. Taniguchi.: UDP-GlcNAc concentration is an important factor in the biosynthesis of beta1,6-branched oligosaccharides: regulation based on the kinetic properties of N-acetylglucosaminyltransferase V. Glycobiology.12(2), 119-27., 2002.
  14. T. Fujii, T. Endo, J. Fujii and N. Taniguchi: Differential expression of glutathione reductase and cytosolic glutathione peroxidase, GPX1, in developing rat lungs and kidneys. , Free Rad. Res., 36, 1041-1049, 2002..
  15. C. X. Gao, K. Honke and N. Taniguchi: Carbohydrate binding activity of annexin V toward a bisecting N-acetylglucosamine. Methods in Enzymol., in press, 2002.
  16. Y. Hasuike, T. Nakanishi, Y. Otaki, M. Nanami, T. Tanimoto, N. Taniguchi and Y. Takamitsu: Plasma 3-Deoxyglucosone Elevation in Chronic Renal Failure is Associated with Increased Aldose Reductase in Erythrocytes. American J. of Kidney Diseases, 40, 464-471, 2002.
  17. K. Honke, N. Ikeda and N. Taniguchi: Differences in recognition of sulfated and sialylated carbohydrate chains. Methods in Enzymol., 637-654, 2002.
  18. T. Kizaki, K. Suzuki, Y. Hitomi, N. Taniguchi, D. Saitoh, K. Watanabe, K. Onoe, N. K. Day, R. A. Good and H. Ohno: Uncoupling protein 2 plays an important role in nitric oxide production of lipopolysaccharide-stimulated macrophages. Proc. Natl. Acad. Sci. USA, 99, 9392-9397, 2002.
  19. T. Kobayashi, T. Kaneto, Y. Iuchi, S. Matsuki, M. Takahashi, I. Sasagawa, T. Nakada and J. Fujii: Localization and physiological implication of aldose reductase and sorbitol dehydrogenase in reproductive tracts and spermatozoa of male rats. J. Andorl., 23, 674-683, 2002.
  20. Y. Miyamoto, Y. H. Koh, W. Che, Y. S. Park, N. Fujiwara, T. Ookawara, K. Suzuki and N. Taniguchi: Dysfunction of antioxidative enzymes and redox regulation under nitrosative stress and glycoxidative stress. International Congress Series, 1245, 23-30, 2002.
  21. J. Niwa, S. Ishigaki, N. Hishikawa, M. Yamamoto, M. Doyu, S. Murata, K. Tanaka, N. Taniguchi and G. Sobue: Dorfin ubiquitylates mutant SOD1 and prebents mutant SOD1-mediated neurotoxicity. J. Biol. Chem., 277, 36793-36798, 2002.
  22. K. Noda, E. Miyoshi, S. Nakahara, H. Ihara, C. X. Gao, K. Honke, S. Yanagidani, Y. Sasaki, A. Kasahara, M. Hori, N. Hayashi and N. Taniguchi: An enzymatic method of analysis for GDP-L fucose in biological samples, involving high-performance liquid chromatography. Anal. Biochem., 310, 100-106, 2002.
  23. K. Noda, E. Miyoshi, T. Kitada, S. Nakahara, H. Ihara, C. X. Gao, K. Honke, Y. Shiratori, H. Moriwaki, Y. Sasaki, A. Kasahara, M. Hori, N. Hayashi and N. Taniguchi: The Enzymatic Basis for the Conversion of Nonfucosylated to Fucosylated a-Fetoprotein by Acyclic Retinoid Treatment in Human Hepatoma Cells: Activation of a1-6 Fucosyltransferase. Tumor Biology, 23, 202-211, 2002.
  24. D. Ogawa, K. Shikata, M. Matsuda, S. Okada, H. Usui, J. Wada, N. Taniguchi and H. Makino: Protective effect of a novel and selective inhibitor of inducible nitric oxide synthase on experimental crescentic glomerulonephritis in WKY rats. Nephrol Dial Transplant, 17, 2117-2121, 2002.
  25. T. Ookawara, T. Kizaki, E. Takayama, N. Imazeki, O. Matsubara, Y. Ikeda, K. Suzuki, J. L. Li, T. Tadakuma, N. Taniguchi and H. Ohno: Nuclear translocation of extracellular superoxide dismutase. Biochem. Biophys. Res. Commun., 296, 54-61, 2002.
  26. K. Sasai, Y. Ikeda, H. Eguchi, T. Tsuda, K. Honke and N. Taniguchi: The action of N-acetylglucosaminyltransferase-V is prevented by the bisecting GlcNAc residue at the catalytic step. FEBS Lett., 522, 151-155, 2002.
  27. K. Suzuki, T. Ookawara, Y. Miyamoto and N. Taniguchi: Enzyme-linked immunosorbent assay for human and rat manganese superoxide dismutases., Methods Enzymol, 349, 129-141, 2002.
  28. H. Yabuuchi, S. Takayanagi, K. Yoshinaga, N. Taniguchi, H. Aburatani and T. Ishikawa: ABCC13, an unusual truncated ABC transporter, is highly expressed in fetal human liver. Biochem. Biophys. Res. Commun., 299, 410-417, 2002.
  29. S. Sakuda, S. Tamura, A. Yamada, J. I. Miyagawa, K. Yamamoto, S. Kiso, N. Ito, S. Higashiyama, N. Taniguchi, S. Kawata and Y. Matsuzawa: NF-kappaB activation in non-parenchymal liver cells after partial hepatectomy in rats: possible involvement in expression of heparin-binding epidermal growth factor-like growth factor., J. Hepatol., 36, 527-533, 2002.

2003

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  1. H. Korekane, T. Taguchi, Y. Sakamoto, K. Honke, N. Dohmae, H. Salminen, S. Toivonen, J. Helin, K. Takio, O. Renkonen and N. Taniguchi: Purification and cDNA cloning of UDP-GlcNAcβ1-3Galβ1-4Glc(NAc)-R[GlcNAc to Gal]β1,6N-acetylglucosaminyltransferase from rat small intestine: A major carrier of dIGnT activity in rat small intestine. Glycobiology, 13, 387-400, 2003.
  2. Y. Miyamoto, Y. H. Koh, Y. S. Park, N. Fujiwara, H. Sakiyama, Y. Misonou, T. Ookawara, K. Suzuki, K. Honke and N. Taniguchi: Oxidative Stress Caused by Inactivation of Glutathione Peroxidase and Adaptive Responses (Minireview). Biol. Chem., 384, 567-574, 2003.
  3. Y. S. Park, Y. H. Koh, M. Takahashi, Y. Miyamoto, K. Suzuki, N. Dohmae, K. Takio, K. Honke and N. Taniguchi: Identification of the Binding Site of Methylglyoxal on Glutathione Peroxidase: Methylglyoxal Inhibits Glutathione Peroxidase Activity via Binding to Glutathione Binding Sites Arg 184 and 185. Free Rad. Res., 37, 205-211, 2003.
  4. K. Sasai, Y. Ikeda, H. Ihara, K. Honke and N. Taniguchi: Caveolin-1 regulates the functional localization of N-acetylglucosaminyltransferase-III within the Golgi apparatus. J. Biol. Chem., 278, 25295-25301, 2003.
  5. Y. Shibukawa, M. Takahashi, I. Laffont, K. Honke and N. Taniguchi: Down-regulation of hydrogen peroxide-induced PKCd activation in N-acetylglucosaminyltransferase III transfected HeLaS3 cells. J. Biol. Chem., 278, 3197-3203, 2003.
  6. R. Takamiya, M. Takahashi, M. Theingi, Y. S. Park, N. Miyazawa, T. Endo, N. Fujiwara, H. Sakiyama, Y. Misonou, Y. Miyamoto, J. Fujii and N. Taniguchi: Glycation Proceeds Faster in Mutated Cu, Zn-Superoxide Dismutases Related to Familial Amyotrophic Lateral Sclerosis. FASEB J., 17, 938-940, 2003.
  7. N. Taniguchi: Discovery of New Functions of Sugar Chains and Glycosyltransferase Gene. JMAJ, 46, 178-184, 2003.
  8. Y. Ito, A. Miyauchi, H. Yoshida, T. Uruno, K. Nakano, Y. Takamura, A. Miya, K. Kobayashi, T. Yokozawa, F. Matsuzuka, N. Taniguchi, N. Matsuura, K. Kuma and E. Miyoshi: Expression of a1,6-fucosyltransferase (FUT8) in papillary carcinoma of the thyroid: its linkage to biological aggressiveness and anaplastic transformation. Cancer Lett., 200, 167-172, 2003.
  9. S. Kiso, S. Kawata, S. Tamura, Y. Inui, Y. Yoshida, Y. Sawai, S. Umeki, N. Ito, A. Yamada, J. Miyagawa, S. Higashiyama, T. Iwawaki, M. Saito, N. Taniguchi, Y. Matsuzawa and K. Kohno: Liver regeneration in heparin-binding EGF-like growth factor transgenic mice after partial hepatectomy. Gastroenterology, 124, 701-707, 2003.
  10. S. Nakahara, E. Miyoshi, K. Noda, S. Ihara, J. Gu, K. Honke, H. Inohara, T. Kubo and N. Taniguchi: Involvment of Oligosaccharide Changes in a5b1Integrin in a Cisplatin-resistant Human Squamous Cell Carcinoma Cell Line. Mol. Cancer Ther., 2, 1207-1214, 2003.Capurro M I, Wanless I R, Sherman M, Deboer G, Shi W, Miyoshi E, Filmus J. (2003) Glypican-3: A novel serum and histochemical marker for hepatocellular carcinoma Gastroenterology 125, 89-97.
  11. S. Niida, M. Kawahara, Y. Ishizuka, Y. Ikeda, T. Kondo, T. Hibi, Y. Suzuki, K. Ikeda and N. Taniguchi: g-Glutamyl Transpeptidase Stimulates RANKL Expression Independent of Its Enzymatic activity and Serves as a Pathological Bone-resorbing Factor. J. Biol. Chem., 279, 5752-5756, 2003.
  12. K. Noda, E. Miyoshi, J. Gu, C. X. Gao, S. Nakahara, T. Kitada, K. Honke, K. Suzuki, H. Yoshihara, K. Yoshikawa, K. Kawano, M. Tonetti, A. Kasahara, M. Hori, N. Hayashi and N. Taniguchi: Relationship between Elevated FX Expression and Increased Production of GDP-L-Fucose, a Common Donor Substrate for Fucosyltaion in Human Hepatocellular Carcinoma and Hepatoma Cell Lines. Cancer Res., 63, 6282-6289, 2003.
  13. K. Inamori, T. Endo, Y. Ide, S. Fujii, J. Gu, K. Honke and N. Taniguchi: Molecular Cloning and Characterization of Human GnT-IX, a Novel b1,6-N-Acetylglucosaminyltransferase that is Specifically Expressed in the Brain. J. Biol. Chem., 278, 43102-43109, 2003.
  14. Fujita T, Machida K, Matsumoto Y, Saito T, Sato N, Takahagi Y, Murakami H, Miyagawa S, Shirakura R, Taniguchi N.: Cynomolgus monkey did not hyperacutely reject skin xenograft of N-acetylglucosaminyltransferase III gene transgenic pig. Transplant Proc., 35, 518, 2003
  15. M. I. Capurro, I. R. Wanless, M. Sherman, G. Deboer, W. Shi, E. Miyoshi, J. Filmus: Glypican-3: A novel serum and histochemical marker for hepatocellular carcinoma Gastroenterology, 125, 89-97, 2003.
  16. Y. Ito, E. Miyoshi, E. Uda, H. Yoshida, T. Uruno, Y. Takamura, A. Miya, K. Kobayashi, F. Matsuzuka, N. Matsuura, K. Kakudo, K. Kuma and A. Miyauchi: 14-3-3 sigma possibly plays a constitutive role in papillary carcinoma, but not in follicular tumor of the thyroid. Cancer Lett., 196, 87-91, 2003.
  17. Y. Ito, A. Miyauchi, H. Yoshida, K. Nakano, Y. Takamura, K. Kobayashi, T. Yokozawa, T. Matsuzuka, N. Taniguchi, N. Matsuura, K. Kuma and E. Miyoshi: Expression of ?1,6fucosyltransferase is bimodal in papillary carcinoma progression. Cancer Lett., 200, 167-172, 2003.
  18. Y. Ito, H. Yoshida, Y. Motoo, E. Miyoshi, JL. Iovanna, C. Tomoda, T. Uruno, Y. Takamura, A. Miya, K. Kobayashi, F. Matsuzuka, N. Matsuura, K. Kuma and A. Miyauchi: Expression and cellular localization of p8 protein in thyroid neoplasms. Cancer Lett., 201, 237-244, 2003.
  19. M. Shigeta, N. Sanzen, M. Ozawa, J. Gu, H. Hasegawa and K. Sekiguchi: CD151 regulates epithelial cell-cell adhesion through PKC- and Cdc42-dependent actin cytoskeletal reorganization. J. Cell. Biol., 163, 165-176, 2003.
  20. T. Kozaki, Y. Matsui, J. Gu, R. Nishiuchi, N. Sugiura, K. Kimata, K. Ozono, H. Yoshikawa and K. Sekiguchi: Recombinant Expression and Characterization of a Novel Fibronectin Isoform Expressed in Cartilaginous Tissues. J. Biol. Chem., 278, 50546-50553, 2003.
  21. J. Gu, S. Nada, M. Okada and K. Sekiguchi: Csk regulates integrin-mediated signals: involvement of differential activation of ERK and Akt. Biochem. Biophys. Res. Commun., 303, 937-977, 2003.
  22. R. Nishiuchi, O. Murayama, H. Fujiwara, J. Gu, T. Kawakami, S. Aimoto, Y. Wada and K. Sekiguchi: Characterization of the ligand binding specificities of integrin ?3?1 and ?6?1 using a panel of purified laminin isoforms containing distinct a chains. J. Biochem., 134, 497-504, 2003.

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21世紀COE

糖鎖治療学

糖鎖工学

グライコフォーラム

大阪大学大学院医学系研究科　生体制御医学　生化学・分子生物学