• HOME
  • Overview
  • Programmed research projects
  • Proposed research projects
  • Research progress / Achievements
  • Links
  • Contact
HOME > Research progress / Achievements > Achievements > 2012-2013: Proposed research project 13
Achievements

2012-2013: Proposed research project 13

Molecular mechanisms involved in the self-organized optic cup formation in vitro
Outline
Research progress
Leader : Mototsugu Eiraku

Original Papers

  • Imuta, Y., Koyama, H., Shi, D., Eiraku, M., Fujimori, T., Sasaki, H. Mechanical control of notochord morphogenesis by extra-embryonic tissues in mouse embryos. Mech. Dev., (in press).
  • Kadoshima, T., Sakaguchi, H., Nakano, T., Soen, M., Ando, S., Eiraku, M., Sasai, Y. Self-organization of axial polarity, inside-out layer pattern, and species-specific progenitor dynamics in human ES cell-derived neocortex. Proc. Natl. Acad. Sci. USA. 110(50): 20284-20289, 2013.
  • Okuda, S., Inoue, Y., Eiraku, M., Sasai, Y., Adachi, T. Apical contractility in growing epithelium supports robust maintenance of smooth curvatures against cell-division-induced mechanical disturbance. J. Biomech. 46(10): 1705-1713, 2013.
  • Nasu, M., Takata, N., Danjo, T., Sakaguchi, H., Kadoshima, T., Futaki, S., Sekiguchi, K., Eiraku, M., Sasai, Y. Robust formation and maintenance of continuous stratified cortical neuroepithelium by laminin-containing matrix in mouse ES cell culture. PLoS One 7(12): e53024, 2012.
  • Okuda, S., Inoue, Y., Eiraku, M., Sasai, Y., Adachi, T. Modeling cell proliferation for simulating three-dimensional tissue morphogenesis based on a reversible network reconnection framework. Biomech. Model. Mechanobiol., 2012.
  • Okuda, S., Inoue, Y., Eiraku, M., Sasai, Y., Adachi, T. Reversible network reconnection model for simulating large deformation in dynamic tissue morphogenesis. Biomech. Model. Mechanobiol., 2012.
  • Nakano, T., Ando, S., Takata, N., Kawada, M., Muguruma, K., Sekiguchi, K., Saito, K., Yonemura, S., Eiraku, M., Sasai, Y. Self-formation of optic cups and storable stratified neural retina from human ESCs. Cell Stem Cell 10(6): 771-785, 2012.
  • Eiraku, M., Sasai, Y. Mouse embryonic stem cell culture for generation of three-dimensional retinal and cortical tissues. Nat. Protoc. 7(1): 69-79, 2011.
  • Eiraku, M., Adachi, T., Sasai, Y. Relaxation-expansion model for self-driven retinal morphogenesis: a hypothesis from the perspective of biosystems dynamics at the multi-cellular level. Bioessays. 34(1): 17-25, 2012.

Review Papers

  • Sasai Y, Eiraku, M., Suga, H. In vitro organogenesis in three dimensions: self-organising stem cells. Development. 139(22): 4111-4121, 2012.
  • Eiraku, M., Sasai, Y. Self-formation of layered neural structures in three-dimensional culture of ES cells. Curr. Opin. Neurobiol. 22(5): 768-777, 2012.
2012-2013: Project 11 Index of Projects 2012-2013: Project 14
PAGE TOP