Reviews
67. Okumura R, Takeda K: The role of the mucosal barrier system in maintaining gut symbiosis to prevent intestinal inflammation. Seminar Immunopathol 47, 2 (2024).
66. Kayama H, Takeda K. Regulation of intestinal epithelial homeostasis by mesenchymal cells. Inflamm Regen 44, 42 (2024).
65. Kayama H, Takeda K. Emerging roles of host and microbially derived bioactive lipids in inflammatory bowel diseases. Eur J Immunol 53, e2249866 (2023).
64. Ogino T, Takeda K. Immunoregulation by antigen-presenting cells in human intestinal lamina propria. Front. Immunol. 14, 1138971 (2023).
63. Kayama H, Takeda K. Manipulation of epithelial integrity and mucosal immunity by host and microbiota-derived metabolites Eur J Immunol 50, 921-931 (2020).
62. Kayama H, Okumura R, Takeda K. Interaction between microbiota, epithelia, and immune cells in the intestine. Annual Reviews Immunol 26;38:23-48 (2020).
61. Maeda Y, Takeda K. Host-microbiota interactions in rheumatoid arthritis. Exp Mol Med. 51, 1-6 (2019).
60. Chen ML, Takeda K, Sundrud MS: Emerging roles of bile acids in mucosal immunity and inflammation. Mucosal Immunol. 12, 851-861 (2019)(2019)
59. Kayama H, and Takeda K: Recasting the Tissue-resident Lymphocyte in Celiac Disease. Immunity50, 549-551 (2019)
58. Kayama H, and Takeda K: Quantification of Trypanosoma cruzi in the tissues and T. cruzi killing assay. Bio Protocol. 7, (2017)
57. Maeda Y, and Takeda K: Role of gut microbiota in rheumatoid arthritis. J. Clin. Med. 6, 60 (2017)
56. Okumura R, and Takeda K: Roles of intestinal epithelial cells in the maintenance of gut homeostasis. Exp. Mol. Med. 49, e338 (2017)
55. Okumura, R. and Takeda, K.: Maintenance of gut homeostasis by the mucosal immune system. Proc Jpn Acad Ser B Phys Biol Sci. 92, 423-435 (2016).
54. Tsai, SH. and Takeda, K.: Regulation of allergic inflammation by the ectoenzyme E-NPP3 (CD203c) on basophils and mast cells. Semin Immunopathol. 38, 571-579 (2016).
53. Takeda, K: A metaboloc bridge between microbiota and humans. Nat. Rev. Immunol. 206 (2016).
52. Kayama, H., and Takeda, K.: Functions of innate immune cells and commensal bacteria in gut homeostasis. J. Biochem. 159, 141-149. (2015).
51. Takeda, K., Tsai, S.H., and Kayama, H.: Regulation of immune responses by ATP-hydrolyzing ecto-enzymes. Inflamm. Regeneration 35, 172-177 (2015).
50. Takeda, K. and Akira, S: Toll-like receptors. Curr. Protoc. Immunol. 109:14.12.1?14.12.10. (2015).
49. Takeda, K.: Cutting-edge research on intestinal immunity and inflammation. Inflamm. Regeneration 35, 1-2 (2015).
48. Kayama, H. and Takeda, K.: Regulation of intestinal inflammation through interaction of intestinal environmental factors and innate immune cells. Inflamm. Regeneration 35, 28-41 (2015).
47. Kayama, H. and Takeda, K.: Polysaccharide A of Bacteroides fragilis: Actions on dendritic cells and T cells. Mol. Cell 54, 206-207 (2014).
46. Kinoshita, M. and Takeda, K.: Microbial and dietary factors modulating intestinal regulatory T cell homeostasis. FEBS Lett. (2014).
45. Kayama, H., Nishimura, J. and Takeda, K.: Regulation of Intestinal Homeostasis by Innate Immune Cells. Immune Netw. 13, 227-234 (2013).
44. Kayama, H., Jeon, S. G., and Takeda, K.: Probiotics and innate immunity: Implication in chronic disease prevention. Probiotics in Prevention of Life Style Disorders (2013)
43. Kayama, H., and Takeda, K.: Regulation of gut homeostasis by innate immunity. Int. Immunol. 24, 673-680 (2012).
42. Kurosaki, T., Saito, T., Kumanogoh, A., Takeda, K. and Kaisho, T.: Dynamism of immune reactions and regulation. Int. Immunol. 24, 473-475 (2012).
41. Vandenbon, A., Teraguchi, S., Akira, S., Takeda, K. and Standley, D.: Toll-like receptor signaling. Wiley Interdiscip. Rev. Syst. Biol. Med. 4, 497-507 (2012).
40. Yamamoto, M. and Takeda, K. Inhibition of ATF6?-dependent host adaptive immune response by a Toxoplasma virulence factor ROP18. Virulence 3, 77-80 (2012).
39. Yamamoto, M. and Takeda, K: A method for the generation of conditional gene-targeted mice. Integrin and Cell Adhesion Molecules: Methods and Protocols. 399-410, 757, (2012).
38. Saiga, H., Shimada, Y. and Takeda, K.: Innate immune effectors in mycobacterial infection. Clin. Dev. Immunol. 2011, 347594 (2011).
37. Yamamoto, M. and Takeda, K.: Current views of Toll-like receptor signaling pathways. Gastroenterol Res Pract. 2010, 240365 (2010).
36. Hedayat, M., Takeda, K. and Rezaei, N.: Prophylactic and therapeutic implications of Toll-like receptor ligands. Med. Res. Rev.32, 294-325 (2010)
35. Kayama, H. and Takeda, K.: The innate immune response to Trypanosoma cruzi infection. Microbes and Infect. 12, 511-517 (2010).
34. Takeda, K.: The lipid A receptor. Lipid A in cancer therapy 53-58, (2009).
33. Kaisho, T. and Takeda, K.: The study of innate immunity in Japan: a historical perspective. Int. Immunol. 21: 313-316 (2009).
32. Atarashi, K., Takeda, K., and Honda, K.: Mechanism of Th17 cell differentiation in the intestinal lamina propria. Inflamm. Regeneration 29, 263-269 (2009).
31. Honda, K., and Takeda, K.: Regulatory mechanisms of immune responses to intestinal bacteria. Mucosal Immunol. 2, 187-196 (2009).
30. Yamamoto, M., and Takeda, K.: Regulation of host immune responses by nuclear I?B proteins. Inflamm. Regeneration. 28, 516-521 (2008).
29. Yamamoto, M., and Takeda, K.: Role of nuclear I?B proteins in the regulation of host immune responses. J. Infect. Chemother. 14, 265-269 (2008).
28. Takeda, K., Yamamoto, M., Honda, K.: Assessing the response of cells to TLR stimulation. Signaling by Toll-like receptors, 1-21 (2008).
27. Takeda, K., and Akira, S.: Toll-like receptors. Curr. Protoc. Immunol. Chapter 14:Unit 14.12. (2007).
26. Takeda, K., Hemmi, H., and Akira, S.: Mechanism for recognition of CpG DNA. Vaccine Adjuvants 71-87 (2005).
25. Takeda, K.: Evolution and integration of innate immune recognition systems: the Toll-like receptors. J. Endotoxin Res.11, 51-55 (2005).
24. Takeda, K., and Akira, S.: Toll-like receptors in innate immunity. Int. Immunol. 17, 1-14 (2005).
23. Takeda, K.: Toll-like receptors and their adaptors in innate immunity. Cur. Med. Chem. AIAA. 4, 3-11 (2005).
22. Akira, S., and Takeda, K.: Functions of Toll-like receptors: lessons from KO mice. C. R. Biol. 327, 581-589 (2004).
21. Takeda, K., and Akira, S.: Biological roles of the STAT family in cytokine signaling. Handbook of Experimental Pharmacology 166, 97-121 (2004).
20. Takeda, K., and Akira, S.: Toll-like receptors: ligands and signaling. Innate Immune Response to Infection 257-270 (2004).
19. Akira, S., and Takeda, K.: Toll-like receptor signaling. Nat. Rev. Immunol. 4, 499-511 (2004).
18. Takeda, K., and Akira, S: Microbial recognition by Toll-like receptors. J. Dermatol. Sci. 34, 73-82 (2004).
17. Takeda, K., and Akira, S.: TLR signaling pathway. Seminar Immunol. 16, 3-9 (2004).
16. Yamamoto, M., Takeda, K., and Akira, S.: TIR domain-containing adaptors define the specificity of TLR signaling. Mol. Immunol. 40, 861-868 (2004).
15. Takeda, K., and Akira, S.: Tissue-specific function of Stat3. Signal Transducers and Activators of Transcription (STATs): Activation and Biology. (2003)
14. Akira, S., Yamamoto, M., and Takeda, K.: Role of adaptors in Toll-like receptor signaling. Biochem. Soc. Trans. 31, 637-642 (2003).
13. Takeda, K., and Akira, S.: Toll receptors and pathogen resistance. Cell. Microbiol. 5, 143-153 (2003).
12. Takeda, K., Kaisho, T., and Akira, S: Toll-like receptors. Annu. Rev. Immunol. 21, 335-376 (2003).
11. Takeda, K., and Akira, S.: Toll receptors. Curr. Proto. Immunol. (2003).
10. Takeda, K., Takeuchi, O., and Akira, S: Recognition of lipopeptides by Toll-like receptors. J. Endotoxin Res. 8, 459-463 (2002).
9. Takeda, K., and Akira, S.: Regulation of innate immune responses through Toll-like receptors. Jpn. J. Infect. Dis. 54, 209-219 (2001).
8. Takeda, K., and Akira, S.: Multi-functional roles of Stat3 revealed by conditional gene targeting. Arch. Immunol. Ther. Exp. 49, 279-283 (2001).
7. Takeda, K., and Akira, S.: Roles of Toll-like receptors in innate immune responses. Genes to Cells 6, 733-742 (2001).
6. Akira, S., Takeda, K., and Kaisho, T.: Toll-like receptors: critical proteins linking innate and acquired immunity. Nature Immunol. 2, 675-680 (2001).
5. Chapman, R. S., Lourenco, P., Tonner, E., Flint, D., Selbert, S., Takeda, K., Akira, S., Clarke, A. R., and Watson, C. J.: The role of Stat3 in apoptosis and mammary gland involution. Conditional deletion of Stat3. Adv. Exp. Med. Biol. 480, 129-138 (2000).
4. Takeda, K., and Akira, S.: Regulation of inflammatory responses through activation of Stat3. Mucosal Immunol. Update, 8, 9-12 (2000).
3. Takeda, K., and Akira, S.: STAT family of transcription factors in cytokine-mediated biological responses. Cytokine Growth Factor Rev. 11, 199-207 (2000).
2. Takeda, K., Kishimoto, T., and Akira, S.: STAT: its relation to Th1/Th2-mediated diseases. Nutrition 13, 987-988 (1997)
1. Takeda, K., Kishimoto, T., and Akira, S.: STAT6: its role in IL-4-mediated biological functions. J. Mol. Med. 75, 317-326 (1997)
