Supercritical FluidNew!!
A supercritical fluid (SCF) is a fluid in which both temperature and pressure exceed the critical point of the gas-liquid phase transition; it can be considered an ideal solvent that combines the solubility of a liquid with the diffusivity of a gas. Because the properties of the solvent can be freely adjusted by controlling temperature […]
The diversity of the physicochemical properties of the metabolomeNew!!
The metabolome is characterized by a wide range of physicochemical properties. These properties include, for example, molecular weight (up to ~2,000), polarity (from low to high), charge characteristics (cationic, zwitterionic, anionic, and uncharged), and molecular stereochemistry (chirality). The figure shows the molecular weights and n-octanol/water partition coefficients (logPow) for a total of 715 standard compounds […]
MetabolomicsNew!!
The Human Genome Project, launched in 1990, led to the complete sequencing of the human genome in 2003. While this project estimated that humans have approximately 30,000 genes, it also revealed that there are numerous biological phenomena that cannot be explained by genomic information alone. Consequently, since 2003, the term “post-genomic era” has been used […]