大阪大学大学院医学系研究科 予防環境医学専攻 遺伝医学講座 遺伝子学  
Home English Site Map
ホーム スタッフ一覧 辻本 賀英 略歴 スタッフ紹介
教授挨拶
研究内容
研究成果
メンバー
催し・報道発表
募集
アクセス
  リンク
フォト
 
研究室紹介:スタッフ紹介
■辻本 賀英
Publication List
1977年 | 1978年 | 1979年 
1981年 | 1983年 | 1984年 | 1985年 | 1986年 
1987年 | 1988年 | 1989年
1990年 | 1991年 | 1992年 | 1993年 | 1994年 
1995年 | 1996年 | 1997年 | 1998年 | 1999年
2000年 | 2001年 | 2002年 | 2003年

注)2004年以降のリストに関しては研究成果をご覧ください。

1990年
52. Adachi, M., Tefferi, A., Greipp, P.R., Kipps, T.J., and Tsujimoto, Y.: Preferential linkage of BCL-2 to immunoglobulin light chain gene in chronic lymphocytic leukemia. J. Exp. Med. 171: 559-564, 1990

53. Adachi, M. and Tsujimoto, Y.: Potential Z-DNA elements surround the breakpoints of chromosome translocation within the 5' flanking region of bcl-2 gene. Oncogene 5: 1653-1657, 1990

54. Akao, Y., Tsujimoto, Y., Finan, J., Nowell, P. C. and Croce, C. M.: Molecular characterization of a t(11;14)(q23;q32) chromosome translocation in a B-cell lymphoma. Cancer Res. 50: 4856-4859, 1990

1991年
55. Akao, Y., Seto, M., Takahashi, T., Kubonishi, I., Miyoshi, I., Nakazawa, S., Tsujimoto, Y., Croce, C. M. and Ueda, R.: Molecular cloning of the chromosomal breakpoint of a B-cell lymphoma with the t(11;14)(q23;q32) translocation. Cancer Res. 51: 1574-1576, 1991

56. Endo, K., Borer, C. H. and Tsujimoto, Y.: Modulation of LFA-1 surface antigen expression by activated H-ras oncogene in EBV-infected human B- lymphoblast cells. Oncogene 6: 1391-1396, 1991

57. Szepetowski, P., Nguyen, C., Pericca-Lostanlen, D., Carle, G. F., Tsujimoto,Y., Birnbaum, D., Theilet, C. and Gaudray, P.: DS11S146 and BCL-1 are physically linked but can be discriminated by their amplification status in human breast cancer. Genomics 10: 410-416, 1991

58. Rosenberg, C. L., Wong, E., Petty, E. M., Bale, A. E., Tsujimoto, Y., Harris, N. L. and Arnold, A.: PRAD1, a candidate BCL-1 oncogene: mapping and expression in centrocytic lymphoma. Proc. Natl. Acad. Sci. USA. 88: 9638-9642, 1991

1992年
59. Tashiro, S., Takechi, M., Asou, H., Takauchi, K., Kyo, T., Dohy, H., Kikuchi, M., Kamada, N. and Tsujimoto, Y.: Cytogenetic 2;18 and 18;22 translocation in chronic lymphocytic leukemia with juxtaposition of bcl-2 and immunoglobulin light chain genes. Oncogene, 7, 573-577, 1992

60. Pettersson, M., Jernberg-Wiklund, H., Larsson, L.-G., Sundstrom, C., Givol, I., Tsujimoto, Y. and Nilsson, K.: Expression of the bcl-2 gene in human multiple myeloma cell lines and normal plasma cells. Blood, 79, 495-502, 1992

61. Szepetoski, P., Simon, M-P., Grosgeorge, J., Hubner, K., Bastard, C., Evans, G. A., Tsujimoto, Y., Birnbaum, D., Theillet, C. and Gaudray, P.: Localozation of 11q13 loci with respect to regional chromosomal breakpoints. Genomics, 12, 738-744, 1992

62. Borzillo, G. V., Endo, K. and Tsujimoto, Y.: Bcl-2 confers growth and survival advantage to IL-7-dependent early pre-B cells which become factor- independent by a multiple process in culture. Oncogene 7, 869-876, 1992

63. Eguchi, Y., Ewert, D. and Tsujimoto, Y.: Isolation and characterization of the chicken bcl-2 gene: expression in a variety of tissues including lymphoid and neuronal organs in embryo and adult. Nucl. Acid Res. 20, 4187-4192, 1992

64. Garcia, I., Martinou, I., Tsujimoto, Y. and Martinou, J.-C.: Prevention of programmed cell death of sympathetic neurons by the bcl-2 proto-oncogene. Science 258, 302-304, 1992

65. Katsumata, M., Siegel, R. M., Louie, D. C., Miyashita, T., Tsujimoto, Y., Nowell, P. C., Green, M. I. and Reed, J. C.: Differential effects of bcl-2 on T and B cells in transgenic mice. Proc. Natl. Acad. Sci. USA., 89, 11376-11380, 1992

1993年
66. Itoh, N., Tsujimoto and Nagata, S.: Effect of bcl-2 on Fas antigen-mediated cell death. J. Immunol., 151, 621-627, 1993

67. Akao, Y., Tsujimoto, Y., Seto, M., Imai, T., Bergeron, D., Berbeau, B. and Ohtsuki, Y.: Long-range mapping of the 11q23 region involved in chromosome aberrations in human tumors by pulse-field gel electrophoresis with a yeast artificial coromosome. Genes Chromo. Cancer, 8, 167-171,1993

68. Tsujimoto, Y.: Human B-cell neoplasia with the t(11;14)(q13;q32) and t(14;18)(q21;q32) chromosome translocations. in The causes and consequences of chromosomal aberrations, ed. Kirsch, I. R. CRC press. p333-350, 1993

1994年
69. Dubois-Dauphin, M., Frankowski, H., Huarte, J., Tsujimoto, Y. and Martinou, J.-C.: Motoneurons overexpressing the bcl-2 protooncogene do not degenerate after axotomy in newborn transgenic mice. Proc. Natl. Acad. Sci. USA. 91, 3309-3313, 1994

70. Ikegaki, N., Katsumata, M., Minna, J. and Tsujimoto, Y.: Expression of bcl-2 protein in small cell lung carcinoma cells. Cancer Res. 54, 6-8, 1994

71. Akao, Y., Ohtsuki, Y., Kataoka, S, Ito, Y. and Tsujimoto, Y.: Multiple subcellular localization of bcl-2: Detection in nuclear outer membrane, endoplasmic reticulum and mitochondrial membranes. Cancer Res. 54, 2468-2471, 1994

72. Yamada T, Yamaoka, S., Goto, T., Nakai, M., Tsujimoto, Y. and Hatanaka, M.: The human T-cell leukemia virus type I tax protein induces apoptosis which is blocked by the bcl-2 protein. J. Virol. 68, 3374-3379, 1994

73. Fujii, Y., Okumura, M., Takeuchi, Y., Inada, K., Nakahara, K., Matsuda, H. and Tsujimoto, Y.: Bcl-2 expression in the thymus and periphery. Cell. Immunol. 155, 335-344, 1994.

74. Otsuki, Y., Misaki, O., Sugimoto, O., Ito, Y., Tsujimoto, Y., and Akao, Y.: Cyclic bcl-2 gene expression in human uterine endometrium during menstrual cycle. Lancet, 343, 28-29, 1994.

75. Sato, N., Hotta, K., Waguri, S., Nitatori, T., Tohyama, K., Tsujimoto, Y. and Uchiyama, Y.: Neronal differentiation of Pc12 cells as a result of prevention of cell death by bcl-2. J. Neurobiol. 25, 1227-12343, 1994.

76. Ikegaki, N., Katsumata, M. and Tsujimoto, Y.: The expression and modulation of proteins associated with physiological cell death in neuroblastoma cells. Prog. Clin. Biol. Res. 385, 117-122, 1994

1995年
77. Kamada, S., Shimono, A, Shinto, Y., Tsujimura, T., Takahashi, T., Noda, T., Kitamura, Y., Kondoh, H. and Tsujimoto, Y.: Bcl-2 deficiency in mice leads to pleiotropic abnormalities: accelerated lymphoid cell death in thymus and spleen, polycystic kidney, hair hypopigmentation and distorted small intestine. Cancer Res. 55, 354-359, 1995.

78. Shimizu, S., Eguchi, Y., Kosaka, H., Kamiike, W., Matsuda, H. and Tsujimoto, Y.: Prevention of hypoxia-induced cell death by Bcl-2 and Bcl-xL. Nature, 374, 811-813, 1995.

790. Ikegaki, N., Katsumata, M., Tsujimoto, Y., Nakagawara, A. and Brodeur, G.M.: Relationship between bcl-2 and myc gene expression in human neuroblastoma. Cancer Lett. 91, 161-168, 1995.

80. Miyazaki, T., Liu, Z.-J., Kawahara, A., Minami, Y., Yamada, K., Tsujimoto, Y., Barsoumian, E. L., Perlmutter, R. M. and Taniguchi, T.: Three distinct IL-2 signaling pathways mediated by bcl-2, c-myc, and lck cooperate in hematopoietic cell proliferation. Cell, 81, 223-231, 1995

81. Akao, Y., Marukawa, O., Morikawa, H., Nakao, K., Kamei, M., Hachiya, T. and Tsujimoto, Y.: The rck/p54 candidate proto-oncogene product is a 54-kilodalton D-E-A-D box protein differentially expressed in human and mouse tissues. Cancer Res. 55, 3444-3449, 1995

82. Shinto, Y., Morimoto, M., Katsumata, M., Uchida, A., Aozasa, K., Okamoto, M., Kurosawa, T., Ochi, T., Greene, M.I. and Tsujimoto, Y.: Moloney murine leukemia virus infection accelerates lymphomagenesis in Em-bcl-2 trasngenic mice. Oncogene, 11, 1729-1736, 1995.

83. Koseki, T., Yamato, K., Krajewski, S., Reed, J., Tsujimoto, Y. and Nishimura, T. Activin A-induced apoptosis is suppressed by Bcl-2. FEBS Letter, 376, 247- 250, 1995.

1996年
84. Suzuki, A., Enari, M., Eguchi, Y., Matsuzawa, A., Nagata, S., Tsujimoto, Y. and Iguchi, T.: Involvement of Fas in regression of vaginal epithelia after ovariectomy and during an estrous cycle. EMBO J. 15, 211-215, 1996.

85. Fukuo, K., Hata, S., Suhara, T., Nakanishi, T., Shinto, Y., Tsujimoto, Y., Morimoto, S. and Ogihara, T.: Nitric oxide induces upregulation of Fas and apoptosis in vascular smooth muscle.Hypertension, 27, 823-826, 1996.

86. Marukawa, O., Akao, Yukihiro, Inazawa, J., Ariyama, T., Abe, T., Naoe, T., Tanimoto, M., Saito, H., Otsuki, Y. and Tsujimoto, Y.: Molecular cloning of the breakpoint of t(11;22)(q23;q11) chromosome translocation in an adult acute myelomonocytic leukemia. British J. Hematol., 92, 687-691, 1996.

87. Tsujimoto, Y.: bcl-2: Antidote for cell death. In Apoptosis (eds. Y. Kuchino & W.E.G. Muller), Springer

88. Iwahashi, H., Hanafusa, T., Eguchi, Y., Nakajima, H., Miyagawa, J., Itoh, N., Tomita, K., Namba, M., Kuwajima, M., Noguchi, T., Tsujimoto, Y. and Matsuzawa, Y.: Cytokine-induced apoptotic cell death in a mouse pancreatic beta cell line: inhibition by bcl-2. Diabetologia, 39, 530-536, 1996

89. Hasegawa, J.-I., Kamada, S., Kamiike, W., Shimizu, S., Imazu, T., Matsuda, H. and Tsujimoto, Y.: Involvement of CPP32/Yama(-like) proteases in Fas-mediated apoptosis. Cancer Res., 56, 1713-1718, 1996.

90. Shimizu, S., Eguchi, Y., Kamiike, W., Itoh, Y., Hasegawa, J.-I., Yamabe, K., Ohtsuki, Y., Matsuda, H. and Tsujimoto, Y.: Induction of apoptosis as well as necrosis by hypoxia and predominant prevention of apoptosis by bcl-2 and bcl-xL. Cacer Res. 56, 2161-2166, 1996

91. Shimizu, S., Eguchi, Y., Kamiike, W., Waguri, S., Uchiyama, Y., Matsuda, H. and Tsujimoto, Y.: Retardation of chemical hypoxia-induced necrotic cell death by Bcl-2 and ICE inhibitors: Possible common steps in apoptosis and necrosis. Oncogene, 12, 2045-2050, 1996.

92. Shimizu, S., Eguchi, Y., Kamiike, W., Matsuda, H. and Tsujimoto, Y.: Bcl-2 expression prevents activation of the ICE protease cascade. Oncogene, 12, 2251-2257, 1996

93. Shimizu, S., Eguchi, Y., Kamiike, W., Waguri, S., Uchiyama, Y., Matsuda, H. and Tsujimoto, Y.: Bcl-2 blocks loss of mitochondrial membrane potential while ICE inhibitors act at a different step during inhibition of death induced by respiratory chain inhibitors. Oncogene, 13, 21-29, 1996

94. Yamamura, K., Kamada, S., Ito, S., Nakagawa, K., Ichihashi, M. and Tsujimoto, Y.: Accelerated disappearance of melanocytes in bcl-2-deficient mice. Cancer Res., 56, 3546-3550, 1996

95. Ishii, N., Wanaka, A., Ohno, K., Matsumoto, K., Eguchi, Y., Mori, T., Tsujimoto, Y. and Tohyama, M.: Localization of bcl-2, bax, and bcl-x mRNA in the developing inner ear of the mouse. Brain Res. 726, 123-128, 1996

96. Matsuda, Y., Kusano, H. and Tsujimoto, Y.: Chromosomal assignment of the bcl-2-related genes, bcl-x and bax, in the mouse and rat. Cytogenet. Cell Genet. 74, 107-110, 1996

97. Kato, H., Sasaki, T., Tamura, K., Minoguchi, S., Shirayoshi, Y., Hamada, Y., Tsujimoto, Y. and Honjo, T.: Functional conservation of mouse Notch receptor family members. FEBS Letters, 395, 221-224, 1996

98. Shimizu, S., Eguchi, Y., Kamiike, W., Akao, Y., Kosaka, H., Hasegawa, J-i., Matsuda, H. and Tsujimoto, Y.: Involvement of ICE family proteases in apoptosis induced by reoxygenation of hypoxic hepatocytes. Am. J. Physiol. 271, G949-G958, 1996

1997年
99. Watanabe, M., Shirayoshi, Y., Koshimizu, U., Hashimoto, S., Yonehara, S., Eguchi, Y., Tsujimoto, Y. and Nakatsuji, N.: Gene transfection of mouse primordial germ cells in vitro and analysis of their survival and growth control. Exp. Cell Res. 230, 76-83, 1997

100. Takahashi, T., Honda, H., Hirai, H. and Tsujimoto, Y.: Overexpression of Bcl-xL prevents bacterial superantigen-induced apoptosis of thymocytes in vitro. Cell Death & Differ. 4, 159-165, 1997

101. Tanabe, H., Eguchi, Y., Kamada, S., Martinou, J.-C. and Tsujimoto, Y.: Susceptibility of cerebellar granule neurons derived from bcl-2-deficient and transgenic mice to cell death. Eur. J. Neurosci., 9, 848-856, 1997

102. Yasuhara, N., Eguchi, Y., Tachibana, T., Imamoto, N., Yoneda, Y. and Tsujimoto, Y.: Essential role of active nuclear transport in apoptosis. Genes to Cells, 2, 55-64, 1997

103. Paumen, M. B., Ishida, Y., Han, H., Muramatsu, M., Eguchi, Y., Tsujimoto, Y. and Honjo, T.: Direct interaction of the mitochondrial membrane protein carnitine palmitoyltransferase I with Bcl-2. Biochem. Biophys. Res. Commun. 231, 523-525, 1997

104. Shigenaga, A., Funahashi, Y., Kimura, K., Kobayakawa, Y., Kamada, S., Tsujimoto, Y. and Tanimura, T.: Targeted expression of ced-3 and Ice induces programmed cell death in Drosophila. Cell Death & Differ. 4, 371-377, 1977

105. Eguchi, Y., Shimizu, S. and Tsujimoto, Y.: Intracellular ATP levels determine cell death fate by apoptosis or necrosis. Cancer Res. 57, 1835-1840, 1997

106. Kamada, S., Funahashi, Y. and Tsujimoto, Y. Caspase-4 and caspase-5, members of the ICE/CED-3 family of cystein proteases, are CrmA-inhibitable proteases. Cell Death & Differ. 4, 473-478, 1997

107. Shigenaga, A., Kimura, K., Kobayakawa, Y., Tsujimoto, Y. and Tanimura, T.: Cell ablation by ectopic expression of cell death genes, ced-3 and Ice in Drosophila. Develop. Growth Differ. 39, 429-436, 1997

108. Kamada, S., Washida, M., Hasegawa, J., Kusano, H., Funahashi, Y. and Tsujimoto, Y.: Involvement of caspase-4(-like) protease in Fas-mediated apoptotic pathway. Oncogene, 15, 285-290, 1997

19. Tsujimoto. Y., Shimizu, S., Eguchi, Y., Kamiike, W. & Matsuda, H. Bcl-2 and Bcl-xL block apoptosis as well as necrosis: possible involvement of common mediators in apoptotic and necrotic signal transduction pathways. Leukemia, Suppl 3:380-2, 1997

110. Ohtsu, M., Sakai, N., Fujita, H., Kashiwagi, M., Gasa, S., Shimizu, S., Eguchi, Y., Tsujimoto, Y., Sakiyama, Y., Kobayashi, K. and Kuzumaki, N.: Inhibition of apoptosis by the actin-regulatory protein gelsolin. EMBO J. 16, 4650-4656, 1997

111. Yasuhara, N., Sahara, S., Kamada, S. and Tsujimoto, Y.: Evidence against a functional site for Bcl-2 downstream of caspase cascade in preventing apoptosis. Oncogene, 15, 1921-1928, 1997

112. Kitanaka, C., Namiki, T., Noguchi, K., Mochizuki, T., Kagaya, S., Chi, S., Hayashi, A., Asai, A., Tsujimoto, Y. and Kuchino, Y.: Caspase-dependent apoptosis of COS-7 cells induced by Bax overexpression: differential effects of Bcl-2 and Bcl-xL on Bax-induced caspase activation and apoptosis. Oncogene,15, 1763-1772, 1997

113 Tsujimoto, Y.: Apoptosis and necrosis: Intracellular ATP level as a determinant for cell death modes. Cell Death & Differ. 4, 429-434, 1997

114. Kagaya, S., Kitanaka, C., Noguchi, K., Mochizuki, T., Sugiyama, A., Asai, A., Yasuhara, N., Eguchi, Y., Tsujimoto, Y. and Kuchino, Y.: A functional role for death proteases in s-Myc- and c-Myc-mediated apoptosis. Mol. Cell. Biol. 17, 6739-6745, 1997

115. Iwahashi, H., Eguchi, Y., Yasuhara, N., Hanafusa, T., Matsuzawa, Y. and Tsujimoto, Y.: Synergistic anti-apoptotic activity between Bcl-2 and SMN implicated in spinal muscular atrophy. Nature,390, 413-417, 1997

1998年
116. Yamabe, K., Shimizu, S., Kamiike, W., Waguri, S., Eguchi, Y., Hasegawa, J., Okuno, S., Yoshioka, Y., Ito, T., Sawa, Y., Uchiyama, Y., Tsujimoto, Y. and Matsuda, H.: Prevention of hypoxic liver cell necrosis by in vivo human bcl-2 gene transfection. B. B. R. C. 243, 217-223, 1998

117. Shimizu, S., Eguchi, Y., Kamiike, W., Funahashi, Y., Mignon, A., Lacronique, V., Matsuda, H. and Tsujimoto, Y.: Bcl-2 prevents apoptotic mitochondrial dysfunction by regulating proton flux. Proc. Natl. Acad. Sci. USA. 95, 1455-1459, 1998

118. Matsushima, M., Fujiwara, T., Takahashi, E., Minaguchi, T., Eguchi, Y., Tsujimoto, Y., Suzumori, K. and Nakamura, Y.: Isolation, mapping, and functional analysis of a novel human cDNA (BNIP3L) encoding a protein homologous to human NIP3. Genes, Chrom. & Cancer, 21, 230-235, 1998

119. Tanaka, N., Sato, M., Lamphier, M. S., Nozawa, H., Oda, E., Noguchi, S., Schreiber, R. D., Tsujimoto, Y. and Taniguchi, T.: Type I interferons are essential mediators of apoptotic death in virally infected cells. Genes to Cells, 3, 29-37, 1998

120. Tanabe, H., Eguchi, Y., Shimizu, S., Martinou, J.-C. and Tsujimoto, Y.: Death-signaling cascade in mouse cerebellar granule neurons. Eur. J. Neurosci. 10, 1403-1411, 1998

121. Kosai, K., Matsumoto, K., Nagata, S., Tsujimoto, Y. and Nakamura, T.: Abrogation of Fas-induced fulminant hepatic failure in mice by hepatocyte growth factor. Biochem. Biophys. Res. Commun. 244, 683-690, 1998

122. Yoshimura, S., Banno, Y., Nakashima, S., Takenaka, K., Sakai, H., Nishimura, Y., Sakai, N., Shimizu, S., Eguchi, Y., Tsujimoto, Y. and Nozawa, Y.: Ceramide formation leads to caspase-3 activation during hypoxic PC12 cell death. Inhibitory effects of Bcl-2 on ceramide formation and caspase-3 activation. J. Biol. Chem. 273, 6921-6927, 1998

123. Saitoh, Y., Eguchi, Y., Hagihara, Y., Arita, N., Watahiki, M., Tsujimoto, Y. and Hayakawa, T. Dose-dependent doxycycline-mediated adrenocorticotropic hormone secretion from encapsulated Tet-On proopiomelanocortin Neuro2A cells in the subarachnoid space. Human Gene Therapy, 9: 997-1002, 1998

124. Kamada, S., Kusano, H., Fujita, H., Ohtsu, M., Koya, R. C., Kuzumaki, N. and Tsujimoto, Y. A cloning method for caspase substrates that uses the yeast two-hybrid system: Cloning of the anti-apoptotic gene gelsolin. Proc. Natl. Acad. Sci. USA., 95: 8532-8537, 1998

125. Kitagawa, K., Matsumoto, M., Tsujimoto, Y., Ohtsuki, T., Kuwabara, K., Matsushima, K., Yang, G., Tanabe, H., Martinou, J-C., Hori, M., Yanagihara, T. Amelioration of hippocampal neuron damage after global ischemia by neuronal overexpression of Bcl-2 in transgenic mice. Stroke, 29: 2616-2621, 1998

126. Okuno, S-i., Shimizu, S., Ito, T., Nomura, M., Hamada, E., Tsujimoto, Y. & Matsuda, H. Bcl-2 prevents caspase-independent cell death. J. Biol. Chem. 273: 34272-7

127. Tsujimoto, Y. Role of Bcl-2 family proteins in apoptosis: apoptosomes or mitochondria? Genes to Cells, 3: 697-707, 1998

128. Narita, M., Shimizu, S., Ito, T., Chittenden, T., Lutz, R. J., Matsuda, H. & Tsujimoto, Y. Bax interacts with the permeability transition pore to induce permeability transition and cytochrome c release in isolated mitochondria. Proc. Natl. Acad. Sci, USA. 95: 14681-14686, 1998

129. Tsujimoto, Y. Prevention of neuronal cell death by Bcl-2. Results Probl. Cell Differ.;24: 137-55, 1998

1999年
130. Ozawa, K., Kuwabara, K., Tamatani, M., Takatsuji, K., Tsukamoto. Y., Kaneda, S., Yanagi, H., Stern, D. M., Eguchi, Y., Tsujimoto, Y., Ogawa, S. and Tohyama, M. ORP150 (150 kDa oxygen-regulated protein) suppresses hypoxia-induced apoptotic cell death. J. Biol. Chem. 274: 6397-6404, 1999

131. Imazu, T., Shimizu, S., Tagami, S., Matsushima, M., Nakamura, Y., Miki, T., Okuyama, A. and Tsujimoto. Y. Bcl-2/E1B 19 kDa-interacting protein 3-ike protein (Bnip3L) interacts with Bcl-2/Bcl-xL and induces apoptosis by altering mitochondrial membrane permeability. Oncogene, 18: 4523-4529, 1999

132. Eguchi, Y., Srinivasan, A., Tomaselli, K. J., Shimizu, S. and Tsujimoto, Y. ATP-dependent steps in apoptotic signal transduction. Cancer Res. 59: 2174-2181, 1999

133. Shimizu, S., Narita, M. and Tsujimoto, Y. Bcl-2 family proteins regulate the release of apoptogenic cytochrome c by the mitochondrial channel VDAC. Nature 399: 483-487, 1999

134. Hamada, Y., Kadokawa, Y., Okabe, M., Ikawa, M., Coleman, J. R. and Tsujimoto, Y. Mutation in ankyrin repeats of the mouse Notch2 gene induces early embryonic lethality. Dev. 126:3 415-3424, 1999

135. Hagiwara, Y., Saitoh, Y., Arita, N., Eguchi, Y., Tsujimoto, Y., Yoshimine, T. and Hayakawa, T. Long-term functional assessment of encapsulated cells transfected with Tet-on system. Cell Transpl., 8: 431-434, 1999

136. Lee, J.-H., Takahashi, T., Yasuhara, N., Inazawa, J., Kamada, S. and Tsujimoto, Y.: Bis, a Bcl-2-binding protein that synergizes with Bcl-2 in preventing cell death. Oncogene, 18: 6183-6190, 1999

137. Ohtsubo, T., Kamada. S., Mikami, T., Murakami, H. and Tsujimoto, Y.: Identification of NRF2, a member of the NF-E2 family of transcription factors, as a substrate for caspase-3(-like) proteases. Cell Death Diff. 6: 865-872, 1999

138. Sahara, S., Aoto, M., Eguchi, Y., Imamoto, N., Yoneda, Y. and Tsujimoto, Y.: Acinus is a caspase-3-activated protein required for apoptotic chromatin condensation. Nature 401: 168-173, 1999

139. Nomura, M., Shimizu, S., Ito, T., Narita, M., Matsuda, H. and Tsujimoto, Y.: Apoptotic cytosol facilitates Bax translocation to mitochondria that involves cytosolic factor regulated by Bcl-2. Cancer Res. 59:5542-5548, 1999

140. Igata, E., Inoue, T., Ohtani-Fujita, N., Sowa, Y., Tsujimoto, Y. and Sakai, T.: Molecular cloning and functional analysis of the murine bax gene promoter. Gene 238: 407-415, 1999

1977年 | 1978年 | 1979年 
1981年 | 1983年 | 1984年 | 1985年 | 1986年 
1987年 | 1988年 | 1989年
1990年 | 1991年 | 1992年 | 1993年 | 1994年 
1995年 | 1996年 | 1997年 | 1998年 | 1999年
2000年 | 2001年 | 2002年 | 2003年

注)2004年以降のリストに関しては研究成果をご覧ください。

ページの上部へ
All rights reserved. Copyright 2003-2009 Molecular Genetics, Osaka University Medical School