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| ■辻本 賀英 |
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| Publication List |
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注）2004年以降のリストに関しては研究成果をご覧ください。
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| 2000年 |
| 141. Tsujimoto, Y. and Shimizu, S.: Bcl-2 family: Life-or-death
switch, FEBS lett. 466: 6-10, 2000
142. Shimizu, Y. and Tsujimoto, Y.: Pro-apoptotic BH3-only Bcl-2 family
members induce cytochrome c release, but not mitochondrial membrane potential
loss, and do not directly modulate VDAC activity. Proc. Natl. Acad. Sci.
USA. 97: 577-582, 2000
143. Sato, K., Eguchi, Y., Kodama, T. and Tsujimoto, Y.: Regions essential
for the interaction between Bcl-2 and SMN, the spinal muscular atrophy
disease gene product. Cell Death & Diff. 7: 374-383, 2000
144. Shimizu, S., Konishi, A., Kodama, T. and Tsujimoto, Y.: BH4 domain
of anti-apoptotic Bcl-2 family members closes VDAC, and inhibits apoptotic
mitochondrial changes and cell death. Proc. Natl. Acad. Sci. USA. 97: 3100-3105,
2000
145. Ueno, H., Kondo, E., Yamamoto-Honda, R., Tobe, K., Nakamoto, T.,
Sasaki, K., Mitani, K., Furusaka, A., Tanaka, T., Tsujimoto, Y., Kadowaki,
T. and Hirai, H.: Association of insulin receptor substrate proteins with
Bcl-2 and their effects on its phosphorylation and antiapoptotic function..
Mol. Biol. Cell, 11: 735-746, 2000
146. Shimizu, S., Ide, T., Yanagida, T. and Tsujimoto, Y. : Electrophysiological
study of a novel large pore formed by Bax and VDAC, which is permeable
to cytochrome c. J. Biol. Chem. 275: 12321-12325, 2000
147. Koya, R. C., Fujita, H., Shimizu, S., Ohtsu, M., Takimoto, M., Tsujimoto,
Y. and Kuzumaki, N. Gelsolin inhibits apoptosis by blocking mitochondrial
membrane potential loss and cytochrome c release. J. Biol. Chem. 275: 15343-15349
148. Tsujimoto, Y. Role of anti-apoptotic Bcl-2 protein in spinal muscular
atrophy. J. Neural Transm. Suppl. 58: 41-52, 2000
149. Shimizu, S., Shinohara, Y. and Tsujimoto, Y. Bax and Bcl-xL independently
regulate apoptotic changes of yeast mitochondria that require VDAC but
not adenine nucleotide translocator. Oncogene 19: 4309-4318, 2000
150. Kusano, H., Shimizu, S., Koya, R.-C., Fujita, H., Kamada, S., Kuzumaki,
N. and Tsujimoto, Y. Human gelsolin prevents apoptosis by inhibiting apoptotic
mitochondrial changes via closing VDAC. Oncogene 19: 4807-4814, 2000
151. Tagami, S., Eguchi, Y., Kinoshita, M., Takeda, M. and Tsujimoto,
Y. A novel protein, RTN-xs, interacts with both Bcl-xL and Bcl-2 on endoplasmic
reticulum and reduces their anti-apoptotic activity. Oncogene 19: 5736-5746,
2000
152. Tsujimoto, Y. and Shimizu, S. VDAC regulation by the Bcl-2 family
of proteins. Cell Death Diff. 7: 1174-1181, 2000
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| 2001年 |
| 153. Hata, S., Fukuo, K., Morimoto, S., Eguchi, Y., Tsujimoto,
Y. and Ogihara, T. Vascular smooth muscle maintains the levels of Bcl-2 in
endothelial cells. Atherosclerosis. 152: 309-316, 2001
154. Shimizu, S., Matsuoka, Y., Shinohara, Y., Yoneda, Y. and Tsujimoto,
Y. Essential role of voltage-dependent anion channel in various forms of
apoptosis in mammalian cells. J. Cell Biol. 152: 237-250, 2001
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| 2002年 |
| 155. Tsujimoto, Y. Regulation of apoptosis
by the Bcl-2 family of proteins. In ﾒApoptosis the molecular biology of
programmed cell deathﾓ (eds. M.D. Jaconson & N. McCarthy) Oxford Univ.
press. 136-160, 2002
156. Tsujimoto, Y. Regulation of cell death by the Bcl-2 family of proteins.
Proc. The 9th International Catecholamine Symp. In press
157. Tsujimoto, Y. and Shimizu, S. The voltage-dependant anion channel:
an essential player in apoptosis. Biochimie 9: 187-193, 2002
158. Tsujimoto, Y. Bcl-2 family of proteins: life-or-death switch in mitochondria.
Bioscience Report. In press
159. Sugiyama, T., Shimizu, S., Matsuoka Y. and Tsujimoto, Y. Activation
of mitochondrial voltage-dependent anion channel by a pro-apoptotic BH3-only
protein Bim. Oncogene, 21: 4944-4956, 2002
160. Akao, Y., Maruyama, W., Shimizu, S., Nakagawa, Y., Shamoto-Nagai,
M., Youdim, M. B. H., Tsujimoto, Y. and Naoi, M. Apoptosis induced by N-methyl(R)salsolinol,
an endogenous neurotoxin, is mediated by mitochondrial permeability transition
and suppressed by Bcl-2 and rasagiline, N-prooargyl-1(R)-aminoindan. J.
Neurochem., In press
161. Lee, M. Y., Kim, S. Y., Shin, S. L., Choi, Y. S., Lee, J. H., Tsujimoto,
Y., Lee, J. H., Reactive astrocytes express bis, a bcl-2-binding protein,
after transient forebrain ischemia. Exp Neurol. 175: 338-346, 2002
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| 2003年 |
162. Nomura, M., Shimizu, S., Sugiyama, T.,Narita, M.,
Ito, T., Matsuda, H. and Tsujimoto, Y. 14-3-3 interacts directly with and
negatively regulates pro-apoptotic Bax. J. Biol. Chem. 278: 2058-2065,
2003
163. Tsujimoto Y. Cell death regulation by the Bcl-2 protein
family in the mitochondria. J Cell. Physiol. 195: 158-167, 2003
164. Konishi, A., Shimizu, S., Hirota, J., Takao, T., Fan, Y., Matsuoka,
Y., Zhang, L., Yoneda, Y., Fujii, Y., Skoultchi, A. I., and Tsujimoto Y.
Involvement of histone H1.2 in apoptosis induced by DNA double-strand breaks.
Cell 114: 673-688, 2003
165. Sugioka, R., Shimizu S., Funatsu, T., Tamagawa, K., Sawa Y., Kawakami,
T and Tsujimoto, Y. BH4-domain peptide from Bcl-xL exerts anti-apoptotic
activity in vivo. Oncogene, 22: 8432-8440, 2003
166. Shinzawa, K. and Tsujimoto, Y. PLA2 activity is required for nuclear shrinkage in caspase-independent cell death. J. Cell Biol., 163, 1219-1230, 2003
167. Tsuruta, F., Sunayama, J., Mori, Y., Hattori, S., Shimizu, S., Tsujimoto, Y., Yoshioka, K. and Gotoh, Y. JNK promotes Bax translocation to mitochondria through phosphorylation of 14-3-3 proteins. EMBO J. in press
168. Hitomi, J., Katayama, T., Eguchi, Y., Kudo, T., Taniguchi, M., Koyama, Y., Manabe, T., Yamagishi, S., Bando, Y., Imaizumi, K., Tsujimoto, Y. and Tohyama M. Involvement of caspase-4 in endoplasmic reticulum stress-induced apoptosis and Ab-indeced cell death. J. Cell Biol. in press
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注）2004年以降のリストに関しては研究成果をご覧ください。
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