Tubulology (Regulation of Polarity Signaling during Morphogenesis, Remodeling, and Breakdown of Epithelial Tubule Structure)

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2012-2013: Proposed research project 18

3D analysis on the dynamic behavior of the biliary system under normal and liver injury conditions using a novel visualization technique

Leader :

Tohru Itoh

Taguchi, K., Hirano, I., Itoh, T., Tanaka, M., Miyajima, A., Suzuki, A., Motohashi, H., Yamamoto, M. Nrf2 enhances cholangiocyte expansion in Pten-deficient livers. Mol. Cell. Biol., (in press).
Takase, H.M., Itoh, T., Ino, S., Wang, T., Koji, T., Akira, S., Takikawa, Y., Miyajima, A. FGF7 is a functional niche signal required for stimulation of adult liver progenitor cells that support liver regeneration. Genes Dev. 27: 169-181, 2013.

Itoh, T., Miyajima, A. Liver regeneration by stem/progenitor cells. Hepatology, (in press).
Itoh, T., Takase, H., Tanaka, M., and Miyajima, A. Liver stem cells (Chapter 13). Regenerative Medicine: From Protocol to Patient, 2nd edition 337-363, 2013.