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Achievements

2012-2013: Proposed research project 20

Role of Mob1 in epithelial tubular structure
Leader : Akira Suzuki

Original Papers

  • Taguchi, K., Hirano, I., Itoh, T., Tanaka, M., Miyajima, A., Suzuki, A., Motohashi, H., Yamamoto, M. Nrf2 enhances cholangiocyte expansion in Pten-deficient livers. Mol. Cell. Biol., (in press).
  • Sugimachi, K., Yokobori, T., Iinuma, H., Ueda, M., Ueo, H., Shinden, Y., Eguchi, H., Sudo, T., Suzuki, A., Maehara, Y., Mori, M., Mimori K. Aberrant Expression of Plastin-3 Via Copy Number Gain Induces the Epithelial-Mesenchymal Transition in Circulating Colorectal Cancer Cells. Ann. Surg. Oncol., (in press).
  • Dong, Y., Sui, L., Yamaguchi, F., Kamitori, K., Hirata, Y., Hossain, MA., Noguchi, C., Katagi, A., Nishio, M., Suzuki, A., Tokuda, M. The expression of PTEN in the development of mouse cochlear lateral wall. NEURO SCIENCE, (in press), 2013.
  • Uchi, R., Kogo, R., Kawahara, K., Sudo, T., Yokobori, T., Eguchi, H., Sugimachi, K., Maehama, T., Mori, M., Suzuki, A., Komune, S., Mimori, K. PICT1 regulates TP53 via RPL11 and is involved in gastric cancer progression. Br. J. Cancer, (in press), 2013.
  • Liao, J., Marumoto, T., Yamaguchi, S., Okano, S., Takeda, N., Sakamoto, C., Kawano, H., Nii, T., Miyamato, S., Nagai, Y., Okada, M., Inoue, H., Kawahara, K., Suzuki, A., Miura, Y., Tani, K. Inhibition of PTEN Tumor Suppressor Promotes the Generation of Induced Pluripotent Stem Cells. Mol. Ther. 21: 1242-1250, 2013.
  • Ishibashi, M., Kogo, R., Shibata, K., Ueo, H., Uchi, R., Matsumura, T., Takano, Y., Sawada, G., Takahashi, Y., Mima, K., Kurashige, J., Akiyoshi, S., Iwaya, T., Eguchi, H., Sudo, T., Sugimachi, K., Suzuki, A., Wakabayashi, G., Mori, M., Mimori, K. Clinical Significance of PICT1 in Patients of Hepatocellular Carcinoma with Wild-Type TP53. Ann. Surg. Oncol., (in press), 2013.
  • Takasuga, S., Horie, Y., Sasaki, J., Sun-Wada, GH., Kawamura, N., Iizuka, R., Mizuno, K., Eguchi, S., Kofuji, S., Kimura, H., Yamazaki, M., Horie, C., Odanaga, E., Sato, Y., Chida, S., Kotani, K., Harada, A., Katada, T., Suzuki, A., Wada, Y., Ohnishi, H., Sasaki, T. Critical roles of type Ⅲ phosphatidylinositol phosphate kinase in murine embryonic visceral endoderm and adult intestine. Proc. Natl. Acad. Sci. USA. 110:1726-1731, 2013.
  • Nishio, M., Hamada, K., Kawahara, K., Sasaki, M., Noguchi, F., Chiba, S., Mizuno, K., Suzuki, SO., Dong, Y., Tokuda, M., Morikawa, T., Hikasa, H., Eggenschwiler, J., Yabuta, N., Nojima, H., Nakagawa, K., Hata, Y., Nishina, H., Mimori, K., Mori, M., Sasaki, T., Mak, TW., Nakano, T., Itami, S., Suzuki, A. Cancer susceptibility and embryonic lethality in Mob1a/1b double-mutant mice J. Clin. Invest. 122(12), 4505-4518, 2012.
  • Miyoshi, K., Yanagi, S., Kawahara, K., Nishio, M., Tsubouchi, H., Imazu, Y., Koshida, R., Matsumoto, N., Tagichi, A., Yamashita, S., Suzuki, A., Nakazato, M. Epithelial Pten controls acute lung Injury and fibrosis by regulating alveolar epithelial cell integrity. AM. J. Respir. Crit. Care Med. 187: 262-275, 2012.
  • Panasyuk, G., Espeillac, C., Chauvin, C., Pradelli, LA., Horie, Y., Suzuki, A., Annicotte, JS., Faias, L., Foretz, M., Verdeguer, F., Pontoglio, M., Ferre, P., Scoazec, JY., Bimbaum, MJ., Ricci, JE., Pende, M. PPARgamma contributes to PKM2 and HK2 expression in fatty liver. Nat. Commun. 3, 672, 2012.

Review Papers

  • Nishio, M., Otsubo, K., Maehama, T., Mimori, K., Suzuki, A. Capturing the Mammalian Hippo: Elucidating Its Role in Cancer. Cancer Sci. 104: 1271-1277, 2013.
  • Suzuk,i A., Kogo, R., Kawahara, K., Sasaki, M., Nishio, M., Maehama, T., Sasaki, T., Mimori, K., Mori, M. A new PICTure of the nucleolar stress. Cancer Sci. 103: 632-637, 2012.