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1998年

Osuka, S., J. Takeda, M. M. Nagiec, R. C. Dickson, and Y. Hirabayashi. Assignment of sptlc2 to murine chromosome 12, resion E by in situ hybridization Cytogenet. Cell. Genet., 82 : 222-223, 1998.

Akaishi, H., K. Takeda, T. Kaisho, R. Shineha, S. Satomi, J. Takeda, and S. Akira. Defective IL-2-mediated IL-2 receptor chain expressionin Stat3-deficient T lymphocytes Int. Immunol., 10: 1747-1751, 1998.

Takeda, K., T. Kaisho, N. Yoshida, J. Takeda, T. Kishimoto, and S. Akira. Stat3 activation is responsible for IL-6-dependent T cell proliferation through preventing apoptosis : Generation and characteraization of T cell specific Stat3-deficient mice. J. Immunol. 161 : 4652-4660, 1998.

Matsuki, M., F. Yamashita, A. Ishida-Yamamoto, K. Yamada, C. Kinoshita, S. Fushiki, E. Ueda, Y. Morishima, K. Tabata, H. Yasuno, M. Hashida, H. Iizuka, M. Ikawa, M. Okabe, G. Kondo, T. Kinoshita, J. Takeda, and K. Yamanishi. Defective stratum corneum and early neonatal death in mice lacking the gene for transglutaminase 1 (keratinocyte transglutaminase) Proc. Natl. Acad. Sci. USA, 95 : 1044-1049, 1998. 

Tomita, S., N. Inoue, Y. Maeda, K. Ohishi, J. Takeda, and T. Kinoshita. A homologue of Saccharomyces cerevisiae Dpm1p is not sufficient for synthesis of dolichol-phosphate-mannose in mammalian cells. J. Biol. Chem., 273: 9249-9254, 1998.

Takahama, Y., K. Ohishi, Y. Tokoro, T. Sugawara, Y. Yoshimura, M. Okabe, T. Kinoshita, and J. Takeda Functional competence of T cells in the absence of GPI-anchored proteins caused by T-cell specific disruption of Pig-a gene. Eur. J. Immunol. 28 : 2159-2166, 1998

Watanabe, R., N. Inoue, B. Westfall, C.H. Taron, P. Orlean, J. Takeda, and T. Kinoshita. The first step of glycosylphosphatidylinositol biosynthesis is mediated by a complex of PIG-A, PIG H, PIG-C, and GPI1 EMBO J. 17 : 877-885, 1998.

Tsujimura, A., , K. Shida, M. Kitamura, M. Nomura, J. Takeda, H. Tanaka, M. Matsumoto, K. Matsumiya, A. Okuyama, Y. Nishimune, M. Okabe, and T. Seya. Molecular cloning of a murine homologue of membrane cofactor protein (MCP, CD46): preferential expression in testicular germ cells. Biochem. J. 330 : 163-168, 1998.

1997年
Matsumoto, M., J. Takeda , N. Inoue, T. Hara, M. Hatanaka, K. Takahashi, S. Nagasawa, H. Akedo, and T. Seya. A novel protein that participates in nonself discrimination of malignant cells by homologous complement. Nature Medicine 3 : 1266-1270, 1997.

Hong, Y., K. Ohishi, N. Inoue, Y. Endo, T. Fujita, J. Takeda, and T. Kinoshita. Structures and chromosomal localizations of the glycosylphosphatidylinositol synthesis gene PIGC and its pseudogene PIGCP1. Genomics 44:347-349, 1997

Tarutani, M., S. Itami, M. Okabe, M. Ikawa, T. Tezuka, K. Yoshikawa, T. Kinoshita, and J. Takeda, Tissue specific knock-out of the mouse Pig-a gene reveals important roles for GPI anchored proteins in skin development. Proc. Natl. Acad. Sci. USA, 94 : 7400-7405, 1997.

Nakamura, N., N. Inoue, R. Watanabe, M. Takahashi, J. Takeda, V. L. Stevens, and T. Kinoshita, Expression cloning of PIG-L, a candidate N-acetylglucosaminylphosphatidylinositol deacetylase. J. Biol. Chem., 272 : 15834-15840, 1997.

Toyomura, K., T. Fujimura, H. Murakami, T. Natsume, T. Shigehisa, N. Inoue, J. Takeda, and T. Kinoshita. Molecular cloning of a pig homologue of membrane cofactor protein (CD46) Int. Immunol., 9: 869-876, 1997.

Nishimura, J., N. Inoue, H. Wada, E. Ueda, P. Pramoonjago, T. Hirota, T. Machii, T. Kageyama, A. Kanamaru, J. Takeda , T. Kinoshita and T. Kitani. A patient with paroxysmal nocturnal hemoglobinuria bearing four independent PIG-A mutant clones. Blood 89: 3470-3476, 1997.

Inoue, N., R. Watanabe, J. Takeda, and T. Kinoshita. PIG-C, one of the three human genes involved in the first step of glycosylphosphatidylinositol biosynthesis is a homologue of Saccharomyces cerevisiae GPI2. Biochem. Biophys. Res. Commun. 226: 193-199, 1996.

Watanabe, R., T. Kinoshita, R. Masaki, A. Yamamoto, J. Takeda, and N. Inoue. PIG-A and PIG-H, which participate in glycosylphosphatidylinositol-anchor biosynthesis, form a protein complex in the endoplasmic reticulum. J. Biol. Chem., 271: 26868-26875, 1996.

Takahashi, M., N. Inoue, K. Ohishi, Y. Maeda, N. Nakamura, Y. Endo, T. Fujita, J. Takeda and T. Kinoshita. PIG-B, a membrane protein of the endoplasmic reticulum with a large lumeral domain, is involved in transferring the third mannose of the GPI anchor. EMBO J. 15: 4254-4261, 1996. 

Kawagoe, K., D. Kitamura, M Okabe, I. Taniuchi, M. Ikawa, T. Watanabe, T. Kinoshita and J. Takeda. GPI-anchor deficient mice: Implication for clonal dominance of mutant cells in paroxysmal nocturnal hemoglobinuria. Blood 87: 3600-3606, 1996.

Ohishi, K., Y. Kurimoto,N. Inoue, Y. Endo, J. Takeda, and T. Kinoshita. Cloning and charaterization of the murine GPI-anchor sythesis gene Pigf , a homologue of the human PIGF gene. Genomics 34: 340-346, 1996.

Hatanaka, M., T. Seya, M. Matsumoto, T. Hara, M. Nonaka, N. Inoue, J. Takeda, and A. Shimizu. Mechanisms by which the surface expression of the glycosylphophatidylinositol-anchored complement regulatory proteins decay accelerating factor (DAF) and CD59 is lost in human leukemia cell lines. Biochem. J. 314: 969-976, 1996.

Nishimura, J., N. Inoue, Y. Azenishi, T. Hirota, T. Akaogi, M. Shibano, K. Kawagoe, E. Ueda, T. Machii, J. Takeda, T. Kinoshita, and T. Kitani. Analysis of the PIG-A gene in a patient who developed a reciprocal translocation of chromosome 12 and paroxysmal nocturnal hemoglobinuria during follow-up of aplastic anemia. American J. Hem. 51: 229-233, 1996.

 
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