Psychophysiology Lab

Overview

We are studying pathophysiological mechanisms of schizophrenia, depression, autism spectrum disorders, dementia and epilepsy using cognitive behavioral methods and neurophysiological methods like Magnetoencephalography (MEG), electroencephalography (EEG), near-infrared spectroscopy (NIRS), positron emission tomography (PET) and transcranial direct current stimulation (tDCS).

Main projects

  • Clinical application of EEG and MEG on psychiatric diseases
  • Physiological mechanism of human EEG components
  • New development of wearable EEG device

Members

  • Masao Iwase M.D Ph.D. (Osaka Prefectural Mental Health and Welfare Center)
  • Ryouhei Ishii M.D Ph.D. (Osaka Metropolitan University)
  • Shun Takahashi M.D. Ph.D.
  • Masahiro Hata M.D. Ph.D.
  • Yuki MIyazaki M.D.

Recent Publications

  1. Cerebrospinal Fluid Biomarkers of Alzheimer's Disease Correlate With Electroencephalography Parameters Assessed by Exact Low-Resolution Electromagnetic Tomography (eLORETA). Hata M, Tanaka T, Kazui H, Ishii R, Canuet L, Pascual-Marqui RD, Aoki Y, Ikeda S, Sato S, Suzuki Y, Kanemoto H, Yoshiyama K, Iwase M. Clin EEG Neurosci pii: 1550059416662119, 2016
  2. Functional connectivity assessed by resting state EEG correlates with cognitive decline of Alzheimer's disease - An eLORETA study. Hata M, Kazui H, Tanaka T, Ishii R, Canuet L, Pascual-Marqui RD, Aoki Y, Ikeda S, Kanemoto H, Yoshiyama K, Iwase M, Takeda M. Clin Neurophysiol. 127(2):1269-78, 2016
  3. Cortical activation patterns in healthy subjects during the traditional Japanese word generation task Shiritori determined by multichannel near-infrared spectroscopy. Nakahachi T, Ishii R, Canuet L, Takahashi H, Ishitobi M, Kamio Y, Iwase M. Neuropsychiatric Electrophysiology 2:2, 2016
  4. Dissociative experiences in epilepsy: Effects of epilepsy-related factors on pathological dissociation, Epilepsy and Behavior, vol. 44, pp. 185-191, 2015.
  5. Detection of EEG-resting state independent networks by eLORETA-ICA method. Frontiers in Human Neuroscience, vol. 9, no. FEB, 2015.
  6. Emotion regulation of neuroticism: Emotional information processing related to psychosomatic state evaluated by electroencephalography and exact low-resolution brain electromagnetic tomography, Neuropsychobiology, vol. 71, no. 1, pp. 34-41, 2015.
  7. Association of cerebrospinal fluid tap-related oscillatory activity and shunt outcome in idiopathic normal-pressure hydrocephalus. Psychogeriatrics, vol. 15, no. 3, pp. 191-197, 2015.
  8. Noninvasive prediction of shunt operation outcome in idiopathic normal pressure hydrocephalus, Scientific Reports, vol. 5, 2015.
  9. Yokukansan and its ingredients as possible treatment options for schizophrenia. Neuropsychiatric Disease and Treatment, vol. 10, pp. 1629-1634, 2014.
  10. Frontal midline theta rhythm and gamma power changes during focused attention on mental calculation: An MEG beamformer analysis. Frontiers in Human Neuroscience, vol. 8, no. JUNE, 2014.
  11. Global complexity and cognitive reserve in MCI. Clinical Neurophysiology, vol. 125, no. 4, pp. 653-654, 2014.
  12. EEG biomarkers of NeuroAIDS. Clinical Neurophysiology, vol. 125, no. 6, pp. 1075-1076, 2014.
  13. EEG connectome: A new candidate for endophenotypes. Clinical Neurophysiology, vol. 124, no. 12, pp. 2289-2290, 2013.
  14. EEG and Neuronal Activity Topography analysis can predict effectiveness of shunt operation in idiopathic normal pressure hydrocephalus patients. NeuroImage: Clinical, vol. 3, pp. 522-530, 2013.
  15. Non-parametric permutation thresholding for adaptive nonlinear beamformer analysis on MEG revealed oscillatory neuronal dynamics in human brain. Proceedings of the Annual International Conference of the IEEE Engineering in Medicine and Biology Society, EMBS, pp. 4807-4810, 2013.
  16. Normalized power variance change between pre-ictal and ictal phase of an epilepsy patient using NAT analysis: A case study. Proceedings of the Annual International Conference of the IEEE Engineering in Medicine and Biology Society, EMBS, pp. 437-440, 2013.
  17. Frequency diversity of posterior oscillatory activity in human revealed by spatial filtered MEG. Journal of Integrative Neuroscience, vol. 12, no. 3, pp. 343-353, 2013.