RESULTS

Micro-RNA-130a-3p regulates gemcitabine-resistance via PPARG in cholangiocarcinoma (Annal. Surg. Oncol., 2017)

In collaboration with the Department of Surgery, Osaka University (Profs. Masaki Mori and Yuichiro Doki), Asukai et al. demonstrated that miR-130a-3p was upregulated in gemcitabine-resistant cholangiocancinoma (CCA) cell lines, and its expression levels were closely related to prognosis of CCA patients. The data support that CCA patients with PPARγ positive were more effective for gemcitabine than those with negative.