RESULTS

Cancer stem cells of the gastrointestinal system (Review: JJCO, 44, 1141, 2014)

In collaboration with the Department of Surgery, Osaka University, Colvin et al. update the recent advances in the understanding of cancer stem cell biology in the gastrointestinal system. This review underscores the aspects of  identification, origin, cell-cycle dormancy, relationship with epithelial-mesenchymal transition, cellular metabolism and the underlying molecular mechanisms.