RESULTS

Drug discovery and development of miRNA-based nucleotide drugs for gastrointestinal cancer (Biomedicines, 2023)

In the collaboration with Department of Gastroenterological Surgery, Osaka University Graduate School of Medicine, Japan (Professors Eguchi and Doki), Dr. Sato has focused on short non-coding RNAs, miRNAs, which play roles in the control of cell growth and differentiation. Given that forced expression of several miRNAs results in the cellular reprograming, it is suggested that the selective introduction of several miRNAs will be able to achieve of anti-cancer effects. Here we emerged microRNA-based therapeutic approaches against gastrointestinal cancers.