RESULTS

Revealing neuropilin expression patterns in pancreatic cancer: from single-cell to therapeutic opportunities (Oncology Letters, 2023)

Given that pancreatic cancer is one of the deadliest human cancers, Meng et al. update information that receptors such as neuropilin-1 (NRP-1) and 2 (NRP-2), which act as co-receptors for vascular endothelial growth factor, transforming growth factor beta, hepatocyte growth factor, fibroblast growth factor, and Semaphorin 3, are involved in the mechanism of therapy resistance. Understanding these mechanisms may help in the development of novel approaches for overcoming refractoriness in pancreatic cancer.