Fat and proteolysis due to methionine, tryptophan, and niacin deficiency leads to alterations in gut microbiota and immune modulation in inflammatory bowel disease (Cancer Sci, 2024)

Fat and proteolysis due to methionine, tryptophan, and niacin deficiency leads to alterations in gut microbiota and immune modulation in inflammatory bowel disease (Cancer Sci, 2024)

 

In an international collaboration with Osaka University, Japan, Dr. Hara investigated the gut microbiome and immune modulation in inflammatory bowel disease (IBD), shedding light on the roles of amino acids in regulating one-carbon metabolism within this condition. His research suggests that controlling nutrient intake may offer a means to reset both gut microbiota composition and host gene expression, ultimately promoting a return to optimal health.