Cyclin G2: a new prognosis marker in pancreatic cancer (Oncol. Lett., 2014)

Cyclin G2: a new prognosis marker in pancreatic cancer (Oncol. Lett., 2014)

Although  a family of cyclins positively regulates the cell cycle to a large extent,  Hasegawa et al. found that  unexpectedly cyclin G2 has been shown to regulate cell proliferation as a tumor suppressor gene,  as the collaboration with the Department of Surgery, Osaka University (Profs. Nagano, Mori and Doki), Research Institute for Microbial Diseases, Osaka University (Prof. Nojima) , and   Cancer Research Institute of Kanazawa University (Prof. Gotoh), Japan. The study demonstrates the candidacy of  decreased CCNG2 expression as a marker for poor prognosis  in pancreatic cancer.