RESULTS

Clinical significance of histone demethylase NO66 in invasive colorectal cancer (Annal. Surg. Oncology, 2016)
In collaboration with the Department of Surgery, Osaka University (Profs. Masaki Mori and Yuichiro Doki), Nishizawa et al. demonstrate that the oncogene-regulated histone demethylase, nucleolar protein 66 (NO66), which is known to work coordinately with the well-characterized oncogene c-MYC, are critical for the determination of biological behavior of invasive colorectal cancer. This would facilitate new drug discovery for the intractable cancer.