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2) Diagnostic PET/SPECT【Oncology PET】
FBPA-PET clinical research
18F-FBPA PET has long been used clinically as a tool for pretreatment evaluation in boron neutron capture therapy, one of radiotherapy. 1)
In recent years, FBPA has been shown to be an L-amino acid transporter 1 (LAT1) -specific PET probe that is highly expressed in many cancer cells, and is attracting attention as a cancer-specific imaging agent. 2)
Currently, we are conducting a study to compare FDG-PET with patients with head and neck cancer and breast tumor.
1) Imahori Y, et al. J Nucl Med. 1998
2) Watabe T, et al. Eur J Nucl Med Mol Imaging. 2017
3) Beshr R, et al. Ann Nucl Med. 2018.


(Glucose metabolism)

(Cancer cell type amino acid transporter LAT1)